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DNA, RNA and Protein Synthesis Summary

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Summary of Topic 4A from A Level Biology AQA Revision book

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DNA, RNA and Protein Synthesis
Created @February 15, 2025 2:54 PM

Class Cells to Systems

Linear Eukaryotic DNA

Linear DNA of eukaryotes are chromosomes

DNA molecule is long and coiled

Molecule wraps around Histones proteins

Proteins support DNA

Tightly wrapped DNA and protein= Compact chromosome



Prokaryotes

Carries DNA as chromosomes but structure is shorter and more circular

Fits into cell by supercoiling



Genes and DNA

Gene is a DNA base sequence

Amino acid sequence creates protein’s primary structure

Arrangements of genetic bases determines arrangement of amino acids
for different polypeptide chains

Amino acid’s made of three base sequence called ‘triplet’

DNA is copied into mRNA as first step in protein synthesis




DNA, RNA and Protein Synthesis 1

, Eukaryotes in DNA Don’t Code for Polypeptides

Genes that don’t code for polypeptides code for functional RNA

Genes that code for polypeptides have sections not relevant to amino
acids

Irrelevant sections are known as introns

Parts of gene coding for amino acids are called exons

Introns are removed during protein synthesis

Some DNA areas are repeated throughout the process, also don’t code for
amino acids. Known as ‘non-coding repeats’




Genes Also Exist as Alleles

Genes can exist as alleles

Alleles contain different arrangement of bases resulting in coding for
varied versions of the same polypeptide




mRNA (Messenger)

Made during transcription process

Carries genetic info from DNA to ribosomes for protein synthesis during
translation stage

Individual polynucleotide strand

Groups of 3 bases are called codons or triplets




tRNA (Transfer)



DNA, RNA and Protein Synthesis 2

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Topic 4a- dna, rna and protein synthesis
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