NBME CBSE ACTUAL EXAM Questions
and Answers Latest Updates 2025
GRADED A+
previously healthy 40 year brought to emergency department by her husband
- 2 day history of fever, lethargy, confusion. PE shows scattered petechiae and
ecchymoses over the lower extremities - 3+ polychromasia and 3+
schistocytes and Low platelets Dx? Correct Ans - Thrombotic
Thrombocytopenia Purpura
49 year old woman - coronary artery disease - BP 140/90 - High Cholesterol,
High LDL (190), High triglycerides (350) - TX with atorvastatin and losartan.
What are the effects on HDL and Triglycerides? Correct Ans - HDL
increased
Triglycerides Decreased
73 yeare old - diffuse weakness and tingling of her arms and legs. Sensation
and vibration and position is decreased in all extremities. What vitamin
deficiency? Correct Ans - Vitamin B12 - (cyanocobalamin)
Tea and Toast - low B12 in diet
15 year old girl - 3 month history of acne - which is the underlying cause of the
,patients acne? Correct Ans - Stimulation of Sebaceous Glands by
androgens
b. ACNE = Propionibacterium ACNE
4 year old from Brazil - PE shows single 12x10cm lesion in the right side of jaw
with diffuse regular edges. Photomicrographs of an incisional biopsy (looks
like Burkitts Lymphoma/ Starry night) - which of the processes most likely to
occur in the region indicated by the arrow? Correct Ans - Apoptosis
b. Endemic Burkitt lymphoma can happen in Brazil as well as Africa (jaw
lesion, puffy face).
51 year old - lump on tongue - 1 pack smoking history for 30 years. 1.5 cm
mass on apex of tongue. It is most appropriate to evaluate which lymph nodes
first for evidence of metastasis? Correct Ans - Submental
15 year old boy - ER - 2 hour history of confusion and agitation - fever,
headache, stif f neck, and vomiting - since returned from summer camp -
patient is hallucinating - lumbar puncture - shows cysts and trophozoites-
most likely pathogen? Correct Ans - a. Olfactory Nerve
Naegleria fowleri
Placebo controlled clinical trial - 5000 pts with essential hypertension. 2500
patients receive new drug and 2500 patients receive placebo. If alpha is set at
, 0.01 instead of 0.05, which of the following is most likely result? Correct Ans -
Significant findings can be reported with greater confidence
A male stillborn is delivered at 32 weeks - Oligohydramnios - absence of a
urethral opening. Which is most likely finding? Correct Ans - Pulmonary
Hypoplasia
A 6 day old - breast fed boy in ED - poor weight gain and irritability since
delivery - Physical exam shows jaundice and hepatomegaly.
The concentration of which of the following metabolites is most likely
increased? Correct Ans - a. Galactose - 1 - phosphate b. Congenital
intolerance to breast milk
A 25-year-old man - comes to ED - severe muscle pain, diffuse, painful
swelling of his neck, underarms, and groin after camping in New Mexico
Generalized scattered black maculae. Examination of the right upper
extremity shows erythematous, solid, tender mass. Mass is draining blood and
necrotic material. The most effective antibiotic for patient disorder will
interfere with which of the following processes? Correct Ans - a.
Ribosomal Assembly
b. Yersenia Pestis
and Answers Latest Updates 2025
GRADED A+
previously healthy 40 year brought to emergency department by her husband
- 2 day history of fever, lethargy, confusion. PE shows scattered petechiae and
ecchymoses over the lower extremities - 3+ polychromasia and 3+
schistocytes and Low platelets Dx? Correct Ans - Thrombotic
Thrombocytopenia Purpura
49 year old woman - coronary artery disease - BP 140/90 - High Cholesterol,
High LDL (190), High triglycerides (350) - TX with atorvastatin and losartan.
What are the effects on HDL and Triglycerides? Correct Ans - HDL
increased
Triglycerides Decreased
73 yeare old - diffuse weakness and tingling of her arms and legs. Sensation
and vibration and position is decreased in all extremities. What vitamin
deficiency? Correct Ans - Vitamin B12 - (cyanocobalamin)
Tea and Toast - low B12 in diet
15 year old girl - 3 month history of acne - which is the underlying cause of the
,patients acne? Correct Ans - Stimulation of Sebaceous Glands by
androgens
b. ACNE = Propionibacterium ACNE
4 year old from Brazil - PE shows single 12x10cm lesion in the right side of jaw
with diffuse regular edges. Photomicrographs of an incisional biopsy (looks
like Burkitts Lymphoma/ Starry night) - which of the processes most likely to
occur in the region indicated by the arrow? Correct Ans - Apoptosis
b. Endemic Burkitt lymphoma can happen in Brazil as well as Africa (jaw
lesion, puffy face).
51 year old - lump on tongue - 1 pack smoking history for 30 years. 1.5 cm
mass on apex of tongue. It is most appropriate to evaluate which lymph nodes
first for evidence of metastasis? Correct Ans - Submental
15 year old boy - ER - 2 hour history of confusion and agitation - fever,
headache, stif f neck, and vomiting - since returned from summer camp -
patient is hallucinating - lumbar puncture - shows cysts and trophozoites-
most likely pathogen? Correct Ans - a. Olfactory Nerve
Naegleria fowleri
Placebo controlled clinical trial - 5000 pts with essential hypertension. 2500
patients receive new drug and 2500 patients receive placebo. If alpha is set at
, 0.01 instead of 0.05, which of the following is most likely result? Correct Ans -
Significant findings can be reported with greater confidence
A male stillborn is delivered at 32 weeks - Oligohydramnios - absence of a
urethral opening. Which is most likely finding? Correct Ans - Pulmonary
Hypoplasia
A 6 day old - breast fed boy in ED - poor weight gain and irritability since
delivery - Physical exam shows jaundice and hepatomegaly.
The concentration of which of the following metabolites is most likely
increased? Correct Ans - a. Galactose - 1 - phosphate b. Congenital
intolerance to breast milk
A 25-year-old man - comes to ED - severe muscle pain, diffuse, painful
swelling of his neck, underarms, and groin after camping in New Mexico
Generalized scattered black maculae. Examination of the right upper
extremity shows erythematous, solid, tender mass. Mass is draining blood and
necrotic material. The most effective antibiotic for patient disorder will
interfere with which of the following processes? Correct Ans - a.
Ribosomal Assembly
b. Yersenia Pestis
