TEST BANK For Katzung's Basic and Clinical Pharmacology, 16th Edition By {Todd W. Vanderah, 2025,} Verified Chapters 1 - 66, Complete Newest Version

TEST BANK FOR BASIC AND CLINICAL PHARMACOLOGY
16TH EDITION KATZUNG’S TESTBANK /ALL CHS 1-
66/COMPLETE GUIDE 2024-2025

,CH 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1.
A nurse working in radiology administers iodine to a hospital client w
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ho is having a computed tomography (CT) scan. The nursing attendant
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working on the oncology unit administers chemotherapy to hospital clien
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ts who have cancer. At the Public Health Department, a nursing attendan
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t administers a measles-mumps-rubella (MMR) vaccine to a 14-month-
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old child as a routine immunization. Which branch of pharmacology best
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describes the actions of all three
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nursing attendants? EF




A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
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Reasoning :->>>>>> EF




Pharmacology is the study of the biologic effects of chemicals. Nursing att
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endants are involved with clinical pharmacology or pharmacotherapeutics,
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which is a branch of pharmacology that deals with the uses of drugs to tr
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eat,prevent, and diagnose disease. The radiology nursing attendant is admi
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nistering a drug to help diagnose a disease. The oncology nursing attenda
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nt is administering a drug to help treat a disease. Pharmacoeconomics incl
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udes any costs involved in drug therapy.
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Pharmacodynamics involves how a drug affects the body and EF EF EF EF EF EF EF EF



pharmacokinetics is how the body acts on the body. EF EF EF EF EF EF EF EF




2.
When involved in phase III drug evaluation studies,
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whatresponsibilities would the nursing attendant have
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?
A) Working with animals who are given experimental drugs
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B) Choosing appropriate hospital clients to be involved in the drug study
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C) Monitoring and observing hospital clients closely for adverse effects
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D) Conducting research to determine effectiveness of the drug
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,ACCURATE CHOICE:-
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Reasoning:->>>>>>

Phase III studies involve use of a drug in a vast clinical population in whi
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chhospital clients are asked to record any symptoms they experience whi
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le taking the drugs. Nursing attendants may be responsible for helping co
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llect and analyzethe information to be shared with the Food and Drug A
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dministration (FDA)but would not conduct research independently beca
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use nursing attendants donot prescribe medications. Use of animals in dr
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ug testing is done in the preclinical trials. Select hospital clients who are
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Finvolved in phase II studies to participate in studies where the participa
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nts have the disease the drug is intended to treat. These hospital clients
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are monitored closely for drug action and adverse effects. Phase I studies
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involve healthy human volunteers who are usually paid for their participa
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tion. Nursing attendants may observe for
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adverse effects and toxicity.
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3.
A physician has ordered intramuscular (IM) injections of morphine, a n
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arcotic, every 4 hours as needed for pain in a motor vehicle accident victim.
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The nursing attendant is aware this drug has a high abuse potential. Und
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er what category would morphine be classified?
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A) Schedule I EF




B) Schedule II EF




C) Schedule III EF




D) Schedule IV EF




ACCURATE CHOICE:-
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Reasoning:->>>>>>

Narcotics with a high abuse potential are classified as Schedule II drugs
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because of severe dependence liability. Schedule I drugs have high abuse
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potential and no accepted medical use. Schedule III drugs have a lesser ab
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use potential than II and an accepted medical use. Schedule IV drugs havel
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ow abuse potential and limited dependence liability.
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4.
What concept is considered when generic drugs are substituted for b
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randname drugs?F
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A) Bioavailability

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B) Critical concentration EF




C) Distribution
D) Half-life
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Reasoning:->>>>>>

Bioavailability is the portion of a dose of a drug that reaches the systemi
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c circulation and is available to act on body cells. Binders used in a gener
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ic drug may not be the same as those used in the brand name drug. Ther
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efore, the way the body breaks down and uses the drug may differ, whic
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h may eliminate a generic drug substitution. Critical concentration is the
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amount ofa drug that is needed to cause a therapeutic effect and should
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not differ between generic and brand name medications. Distribution is t
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he phase of pharmacokinetics, which involves the movement of a drug to
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the bodys tissues and is the same in generic and brand name drugs. A dr
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ugs half- EF



life isthe time it takes for the amount of drug to decrease to half the pea
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k level, which should not change when substituting a generic medicatio
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n.


5. A nursing attendant is assessing the hospital clients home medication use. After
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listening to the hospital client list current medications, the nursing atten
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dant asks what priority question?
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A) Do you take any generic medications?
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B) Are any of these medications orphan drugs?
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C) Are these medications safe to take during pregnancy?
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D) Do you take any over-the-counter medications?
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ACCURATE CHOICE:- EF D
Reasoning:->>>>>>

It is important for the nursing attendant to specifically question use of o
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ver- the- EF



counter medications because hospital clients may not consider them imp
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ortant. The hospital client is unlikely to know the meaning of orphan dr
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ugs unless they too are primary health care providers. Safety during preg
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nancy, use of a genericmedication, or classification of orphan drugs are th
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ings the hospital client would be unable to answer but could be found in
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reference books if the nursing attendant wishes to research them.
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