GNRS 5669 Exam 4 Questions and
Answers| Latest Update
Respiratory/inhalation anthrax: -fever, malaise, nonproductive cough, sweats, chest
discomfort
-ronchi on exam
-CXR- mediastinal widening, pleural effusion
GI antrax: -nausea, vomiting, fever, abd pain, hematemesis, bloody diarrhea
Tx: same
children- cipro 30mg/kg q 8hrs
Oropharyngeal anthrax: -fever with unilateral or bilateral swelling
-sore throat
-ulcer at base of tongue
Brucellosis: -Goats
-Inhalation- low infection
-unpasteurized dairy products
S/s: fever, anorexia, headache myalgias, arthralgias, severe fatigue, hepatosplenomegaly
-spondylitis
,-anxiety, loss of concentration
Tx:
->10 and not pregnant: docycycline 100-200 mcg/d and Rifampin 600-900 mg/d for 6 wks
-for first 14-21 days doxy + streptomycin 1g IM
Plague: -transmitted to humans by infected rodent fleas (bubonic)
-aerosol (pneumonic)
Bubonic plague: -very swollen tender lymph gland "bubo"
-fever, chills, headache,
-hx of exposure to infected rodents, rabbits, or fleas
Septicemic plague: fever
chills
hypotension
n/v
Pneumonic plague: fever/chills
malaise
HA
Hemoptysis
, Tularemia: -gram negative coccobacillus
-tick, mosquitos, deerflies
S/s: chills, myalgia, HA, painful maculopapular lesion at site of entry and inflamed lymph nodes
Tx:
SEVERE- Streptomycin 10mg/kg q 12hrs 7-10 days, Gentamycin 5mg/kg q 8hrs 7-10 days
MILD- doxy, cipro
Ricin: -protein toxin from beans of castor plant
Respiratory s/s: fever, cough, dyspnea, nausea, ARDs, athralgias
Ingestion s/s: necrosis of GI epithelium, local hemorrhage, hepatic, splenic, and renal necrosis
Tx:
Supportive- gastric lavage, volume replacement, ventilation and resp support
Smallpox: S/s: sudden onset of fever and malaise
macules to papules to vesicles to pustules and scabs
Answers| Latest Update
Respiratory/inhalation anthrax: -fever, malaise, nonproductive cough, sweats, chest
discomfort
-ronchi on exam
-CXR- mediastinal widening, pleural effusion
GI antrax: -nausea, vomiting, fever, abd pain, hematemesis, bloody diarrhea
Tx: same
children- cipro 30mg/kg q 8hrs
Oropharyngeal anthrax: -fever with unilateral or bilateral swelling
-sore throat
-ulcer at base of tongue
Brucellosis: -Goats
-Inhalation- low infection
-unpasteurized dairy products
S/s: fever, anorexia, headache myalgias, arthralgias, severe fatigue, hepatosplenomegaly
-spondylitis
,-anxiety, loss of concentration
Tx:
->10 and not pregnant: docycycline 100-200 mcg/d and Rifampin 600-900 mg/d for 6 wks
-for first 14-21 days doxy + streptomycin 1g IM
Plague: -transmitted to humans by infected rodent fleas (bubonic)
-aerosol (pneumonic)
Bubonic plague: -very swollen tender lymph gland "bubo"
-fever, chills, headache,
-hx of exposure to infected rodents, rabbits, or fleas
Septicemic plague: fever
chills
hypotension
n/v
Pneumonic plague: fever/chills
malaise
HA
Hemoptysis
, Tularemia: -gram negative coccobacillus
-tick, mosquitos, deerflies
S/s: chills, myalgia, HA, painful maculopapular lesion at site of entry and inflamed lymph nodes
Tx:
SEVERE- Streptomycin 10mg/kg q 12hrs 7-10 days, Gentamycin 5mg/kg q 8hrs 7-10 days
MILD- doxy, cipro
Ricin: -protein toxin from beans of castor plant
Respiratory s/s: fever, cough, dyspnea, nausea, ARDs, athralgias
Ingestion s/s: necrosis of GI epithelium, local hemorrhage, hepatic, splenic, and renal necrosis
Tx:
Supportive- gastric lavage, volume replacement, ventilation and resp support
Smallpox: S/s: sudden onset of fever and malaise
macules to papules to vesicles to pustules and scabs
