Which of the following does NOT affect a drug's effect, metabolism and toxicity? -
Answer-A. Physiological altercations of advancing age
B. Generic variations
C. Environmental factors
D. Generic versus brand-nameform
ANSWER: D. GENERIC BRAND-NAMEFORM
Which of the following vital signs is NOT affected by he changes of aging? - Answer-
A. Pulse
B. Blood pressure
C. Respirations
D. Temperature
ANSWER: D. TEMPERATURE
Which of the following is NOT a change that occurs in the cardiovascular system
associated with aging? - Answer-A. The heart pumps less forcefully and moves less
blood with each beat
B. The heart has less of an ability to gear up when the body is under stress
C. Hypo tension develops
D. There is less blood flow to all parts of the body
ANSWER: C. HYPO TENSION DEVELOPS
Which of the following is NOT a change that occurs in the respiratory system that is
associated with aging? - Answer-A. The lungs have less of an ability to expand
B. Breathing is shallower
C. Respirations slows down to less than the normal 16-20 breath per minute
D. Not as much oxygen is supplied to the body
ANSWER: C. RESPIRATION SLOWS DOWN TO LESS THAN THE MORMAL 16-
20 BREATH PER MINUTE
Which of the following is NOT a change in the nervous system that is associated with
deceased blood flow an oxygen supply to the brain? - Answer-A. Memory is affected
B. The ability to make decisions is affected
C. Confused thinking result
D. People experience difficulty in understanding the meaning of words
ANSWER: D. PEOPLE EXPERIENCE DIFFICULTY IN UNDERSTANDING THE
MEANING OF WORDS
Which of the following is NOT a change that occurs in the sensory system that is
associated with aging? - Answer-A. Eyes have difficulty adjusting to light
B. Ears do not hear the lower pitched sounds
,C. Taste is dulled
D. Sense if touch is dulled
ANSWER: D. EARS DO NOT HEAR THE LOWER PITCHED SOUNDS
Which of the following results from the interaction between sedatives and alcohol? -
Answer-A. Hypertension
B. Hyperkalemia
C. Increased sedation
D. Decreased absorption of sedatives
ANSWER: INCREASED SEDATION
Which of the following results from combination of warfarin (Coumadin) and aspirin
or nonsteroidal anti-inflammatory drugs (NSAID)? - Answer-A. Increased action of
warfarin
B. Decreased action of warfarin
C. Increased action of aspirin or nonsteroidal anti- inflammatory drugs (NSAID)
D. Decreased action of aspirin or nonsteroidal anti-inflammatory drugs (NSAID)
ANSWER: A. INREASED ACTION OF WARFARIN
Which of the following statements describes why wastes are excreted more slowly in
the older adult? - Answer-A. The kidneys do not filter the blood as efficiently
B. Eating is less pleasurable because taste and smell are dulled
C. Older adult produce less stomach acid than normal
D. Teeth are lost and eating become difficult
ANSWER: THE KIDNEYS DO. NOT FILTER AS EFFICIENTLY
Which of the following statements about pharmacokinetics in the older adult is NOT
true? - Answer-A. Absorption becomes slower
B. Biotransformation becomes slower
C. Excretion becomes slower
D. Distribution becomes slower
ANSWER: EXCRETION BECOMES SLOWER
Which of the following affects absorption and distribution? - Answer-A. Slower blood
circulation, slower absorption of medications through the intestines
B. Less blood flow to the kidneys, slower excretion of medications
C. Trouble swallowing oral medication because of missing teeth, constipation
D. Less stomach secretions slowing down of muscular movements of the digestive
tract
ANSWER: A. SLOWER BLOOD CIRCULATION. SLOWER ABSORPTION OF
MEDICATIONS THROUGH THE INTESTINES
Which of the following may occur in the older adult, because drugs stay in effect
longer and can build up in the body with repeated doses? - Answer-A. Synergism
, B. Cumulative effect
C. Idiosyncratic effect
D. Tolerance
ANSWER: B. CUMULATIVE EFFECT
What occurs at aging? - Answer-A. Cumulative
B. Abnormal drug reaction
C. Tolerance
D. Synergism
ANSWER: B. ABNORMAL DRUG REACTION
Which of the following can occur in the older adult as a result of changes in kidney
function? - Answer-A. Cumulative effect
B. Abnormal drug reaction
C. Tolerance
D. Synergism
ANSWER: A. CUMULATIVE EFFECT
Which of the following guidelines should be followed when administering medication
to older adults? - Answer-A. Give lower, more frequent doses
B. Give lower, less frequent doses
C. Give larger, less frequent doses
D. Give larger, more frequent doses
ANSWER: B. GIVE LOWER, LESS FREQUENT DOSES
Adjustments are made in the forms of medication given and their routes to aid in? -
Answer-A.Absorption
B. Disruption
C. Biotransformation
D. Excretion
ANSWER: ABSORPTION
What are two other age-related factors that have an impact on the effect of a drug? -
Answer-A. Disease and other drug
B. Changes in muscle tone and skin elasticity
C. Gender and hormone secretion
D. Activity level and emotional state
ANSWER: ACTIVITY LEVEL AND EMOTIONAL STATE
Which of the following terms describes the use of a number of different drugs by a
patient who may have several different problems? - Answer-A. Pharmacokinetics
B. Cumulation
C. Polypharmacy
D. Polychemotherapy