Test bank Kaplan
Chemistry (Ch 14,49,50,51,55,56) Test
Bank Kaplan
Question Answer
1. It is of particular importance to
monitor drug levels in patients for
drugs that have a _____ index. A a. low, significant toxicity from the
therapeutic index of 2.0 is associated drug
with a high likelihood of the patient
experiencing _____.
d. at varied times and based on the
2. Blood Samples should be
characteristic of the particular drug,
collected for therapeutic drug
rout of administration, and intent of
monitoring:
the drug.
3. Where will an acidic drug with pK
of 3.5 have the greatest chance for A. The stomach
absorption by passive diffusion?
4. Which of the following are 1. to make the drug more water
considered goals of metabolism? soluble 2. to make the drug less active
,5. The primary driving force for
drugs to move from the point of
absorption to the site of action is
D. Passive transport, passive transport
____, and the primary driving force
for drugs to leave the site of action
following a single dose is_____.
6. Some active drugs are known to
be enzymatically metabolized active
D. The active form of the prodrug is
metabolites but are no considered
unstable, not readily soluble, or poorly
prodrugs. Which of the following
absorbed.
explains the difference between
these drugs and prodrugs?
7. In general consideration of drug
blood level and the time a drug
B. The more rapidly the peak
spends in the body before
concentration is attained, the longer
elimination under normal
the period of time the drug will spend
physiological conditions, which of
in the body.
the statements below is true
following a single dose of drug?
8. Considering the administration of
a single does of a hypothetical drug
by different routes, which of the
C. Intravenous, intramuscular, oral
following gives the correct order of
attaining peak concentration of the
drug in the blood stream
Different drug manufacturers D. The area under the blood level-
, influence the lvl time curve after a
single dose and release from diff
time curve for each formulation will be
formulations. Describe the
the same
correlations between the diff
formulations.
10. The 2 main organs associated w/
the elimination of drugs are the
kidney and the liver. What would be
C. The peak concentration will
the effect on the blood lvl-time
increase, and the duration of time the
curve following the administration of
drug spends in the body will increase
a single dose of a medication in the
presence of liver disease or renal
failure
11. Given that a drug has a half-life
of 10 hours and is administered at a
dosing internal of slightly less than
C. 40 hours
the half-life, approximately how long
will it take to reach the steady-state
interval?
12. A situation where the amount of
drug excreted between two doses is
A. A steady- state
equal to the previous dose
administered is known as.
13. Kinetic processes related to the B. first order kinetics
fate of a drug in the body, where the
rate of change of drug concentration
Chemistry (Ch 14,49,50,51,55,56) Test
Bank Kaplan
Question Answer
1. It is of particular importance to
monitor drug levels in patients for
drugs that have a _____ index. A a. low, significant toxicity from the
therapeutic index of 2.0 is associated drug
with a high likelihood of the patient
experiencing _____.
d. at varied times and based on the
2. Blood Samples should be
characteristic of the particular drug,
collected for therapeutic drug
rout of administration, and intent of
monitoring:
the drug.
3. Where will an acidic drug with pK
of 3.5 have the greatest chance for A. The stomach
absorption by passive diffusion?
4. Which of the following are 1. to make the drug more water
considered goals of metabolism? soluble 2. to make the drug less active
,5. The primary driving force for
drugs to move from the point of
absorption to the site of action is
D. Passive transport, passive transport
____, and the primary driving force
for drugs to leave the site of action
following a single dose is_____.
6. Some active drugs are known to
be enzymatically metabolized active
D. The active form of the prodrug is
metabolites but are no considered
unstable, not readily soluble, or poorly
prodrugs. Which of the following
absorbed.
explains the difference between
these drugs and prodrugs?
7. In general consideration of drug
blood level and the time a drug
B. The more rapidly the peak
spends in the body before
concentration is attained, the longer
elimination under normal
the period of time the drug will spend
physiological conditions, which of
in the body.
the statements below is true
following a single dose of drug?
8. Considering the administration of
a single does of a hypothetical drug
by different routes, which of the
C. Intravenous, intramuscular, oral
following gives the correct order of
attaining peak concentration of the
drug in the blood stream
Different drug manufacturers D. The area under the blood level-
, influence the lvl time curve after a
single dose and release from diff
time curve for each formulation will be
formulations. Describe the
the same
correlations between the diff
formulations.
10. The 2 main organs associated w/
the elimination of drugs are the
kidney and the liver. What would be
C. The peak concentration will
the effect on the blood lvl-time
increase, and the duration of time the
curve following the administration of
drug spends in the body will increase
a single dose of a medication in the
presence of liver disease or renal
failure
11. Given that a drug has a half-life
of 10 hours and is administered at a
dosing internal of slightly less than
C. 40 hours
the half-life, approximately how long
will it take to reach the steady-state
interval?
12. A situation where the amount of
drug excreted between two doses is
A. A steady- state
equal to the previous dose
administered is known as.
13. Kinetic processes related to the B. first order kinetics
fate of a drug in the body, where the
rate of change of drug concentration
