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PCOL 838 Midterm Exam 2025 Graded A+ Questions with 100% Correct Answers

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PCOL 838 Midterm Exam 2025 Graded A+ Questions with 100% Correct Answers what are the four major islet cell types and their functions? - - beta cells = secrete insulin (60%) - alpha cells = secrete glucagon (30%) - delta cells = secrete somatostatin (10%) - pancreatic polypeptide secreting cell (1%) what is the effect of alpha cells (glucagon) on other islet cells? - it stimulates beta cells (insulin) and delta cells (somatostatin) what is the effect of delta cells (somatostatin) on other islet cells? - it inhibits beta cells (insulin) and alpha cells (glucagon) what is the effect of beta cells (insulin) on other islet cells? - it inhibits alpha cells (glucagon)

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PCOL 838 Midterm Exam 2025 Graded
A+ Questions with 100% Correct
Answers
what are the four major islet cell types and their functions? - - beta cells = secrete insulin (60%)



- alpha cells = secrete glucagon (30%)



- delta cells = secrete somatostatin (10%)



- pancreatic polypeptide secreting cell (1%)



what is the effect of alpha cells (glucagon) on other islet cells? - it stimulates beta cells (insulin) and
delta cells (somatostatin)



what is the effect of delta cells (somatostatin) on other islet cells? - it inhibits beta cells (insulin) and
alpha cells (glucagon)



what is the effect of beta cells (insulin) on other islet cells? - it inhibits alpha cells (glucagon)



what do beta cells secrete?



a. insulin



b. glucagon



c. somatostatin - a. insulin



what do alpha cells secrete?



a. insulin

, b. glucagon



c. somatostatin - b. glucagon



what do delta cells secrete?



a. insulin



b. glucagon



c. somatostatin - c. somatostatin



what does the presence of C peptide mean? - it means insulin is being made



what is the effect of insulin responsive cells (IRCs) on the body? - - liver and muscle = decrease
gluconeogenesis and glycogenolysis



- adipocytes = increased lipogenesis and adipogenesis



how is glucose transported into the cell? - GLUT4 transporter fuses with the membrane and causes
glucose uptake



what is the end result of PI3K signaling?



a. necrosis



b. phagocytosis



c. apoptosis



d. entosis - c. apoptosis

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