NUR565 MIDTERM EXAM AND STUDY GUIDE EXAM|
ADVANCED PHARMACOLOGY FUNDAMENTAL LATEST
2025/2026 ACTUAL EXAM |COMPLETE 300 QUESTIONS
AND CORRECT DETAILED ANSWERS (VERIFIED ANSWERS)
|ALREADY GRADED A+ |CHAMBERLAIN.
What is used to calculate a patients overdose risk? - ANSWER - MME total
morphine milligram equivalent per day
When should you refer a patient to a pain specialist? - ANSWER - Referral
to a pain specialist is required for patients who take 120 mg per day of
morphine milligram equivalents
What is the PDMP? - ANSWER - Prescription Drug Monitoring Program
Used to effectively track patient’s-controlled substance uses across
different health facilities (in the same state)
When should Narcan be prescribed? - ANSWER - factors that increase risk
for opioid overdose, such as history of overdose, history of substance use
disorder, higher opioid dosages (≥50 MME/day), or concurrent
benzodiazepine use, are present.
Behaviors that predict substance abuse - ANSWER - NIDA-Modified
ASSIST
pg. 1
,Examples of schedule II meds - ANSWER - Some examples of Schedule II
drugs are: combination products with less than 15 milligrams of
hydrocodone per dosage unit (Vicodin), cocaine, methamphetamine,
methadone, hydromorphone (Deluded), meperidine (Demerol), oxycodone
(OxyContin), fentanyl, Dexedrine, Adderall, and Ritalin
DEA description of scheduled drugs - ANSWER - Drugs, substances, and
certain chemicals used to make drugs are classified into five (5) distinct
categories or schedules depending upon the drug's acceptable medical use
and the drug's abuse or dependency potential. The abuse rate is a
determinate factor in the scheduling of the drug; for example, Schedule I
drugs have a high potential for abuse and the potential to create severe
psychological and/or physical dependence.
Treatment of chronic pain - ANSWER - Nonpharmacologic therapy and
nonopioid pharmacologic therapy are preferred for chronic pain.
Benefits > Risks
Establish goals
Start with immediate release meds
start with the lowest effective dose
eval within 1-4 wks.
What is methadone? - ANSWER - Nonpharmacologic therapy and
nonopioid pharmacologic therapy are preferred for chronic pain.
What is the black box warning for methadone? - ANSWER - Methadone
can cause life-threatening QT prolongation and severe respiratory
depression. Because of the long half-life of methadone, it should be
prescribed only by health care providers with special training in chronic
pain management.
pg. 2
,factors for substance abuse - ANSWER - Drug related: availability, effect
and tolerability.
Predisposition: genetics, personality and psych
Environment: family, society, peer group, life events, stress
Benefit of using buprenorphine and naloxone - ANSWER -
Buprenorphine/naloxone combinations like Suboxone work in the body by
binding to opioid receptors, which help regulate hormones, physical
movement, emotions, and pleasure.
Order of HTN medications typically prescribed - ANSWER - thiazide-type
diuretic
calcium channel blocker (CCB)
angiotensin-converting enzyme inhibitor (ACEI)
angiotensin receptor blocker (ARB).
What is the best antihypertensive for someone with diabetes? - ANSWER -
ACEIs, ARBs, CCBs, and diuretics (in low doses).
best HTN med for pregnancy? - ANSWER - labetalol and methyldopa
What hen meds are contraindicated in pregnancy? - ANSWER - ACEIs,
ARBs, and DRIs,
Clonidine - ANSWER - site of action: brainstem
Suppression of sympathetic outflow decreases sympathetic stimulation of
the heart and blood vessels.
pg. 3
, Mecamylamine - ANSWER - site of action: Sympathetic ganglia
Ganglionic blockade reduces sympathetic stimulation of the heart and
blood vessels.
Reserpine - ANSWER - site of action: Adrenergic nerve terminals
Reduced norepinephrine release decreases sympathetic stimulation of the
heart and blood vessels.
What meds do not work as well for African Americans? - ANSWER - n
contrast, monotherapy with β blockers or ACEIs is less effective in African
Americans than in Caucasians. Nonetheless, β blockers and ACEIs should
be used if they are strongly indicated for a comorbid condition
what to prescribe in response to fibrotic changes? - ANSWER -
Sacubitril/valsartan (Entresto).
Aldosterone Antagonists (Spiro lactone)
Direct Renin Inhibitors
β Blockers
effects of cardiac glycosides - ANSWER - Digoxin exerts a positive
inotropic action on the heart. That is, the drug increases the force of
ventricular contraction and can thereby increase cardiac output
what happens when digoxin and quinidine are combined? - ANSWER -
when quinidine is Coad ministered with digoxin, quinidine inhibition of P-gp
results in an increase in digoxin absorption and a reduction of digoxin
elimination,
pg. 4
ADVANCED PHARMACOLOGY FUNDAMENTAL LATEST
2025/2026 ACTUAL EXAM |COMPLETE 300 QUESTIONS
AND CORRECT DETAILED ANSWERS (VERIFIED ANSWERS)
|ALREADY GRADED A+ |CHAMBERLAIN.
What is used to calculate a patients overdose risk? - ANSWER - MME total
morphine milligram equivalent per day
When should you refer a patient to a pain specialist? - ANSWER - Referral
to a pain specialist is required for patients who take 120 mg per day of
morphine milligram equivalents
What is the PDMP? - ANSWER - Prescription Drug Monitoring Program
Used to effectively track patient’s-controlled substance uses across
different health facilities (in the same state)
When should Narcan be prescribed? - ANSWER - factors that increase risk
for opioid overdose, such as history of overdose, history of substance use
disorder, higher opioid dosages (≥50 MME/day), or concurrent
benzodiazepine use, are present.
Behaviors that predict substance abuse - ANSWER - NIDA-Modified
ASSIST
pg. 1
,Examples of schedule II meds - ANSWER - Some examples of Schedule II
drugs are: combination products with less than 15 milligrams of
hydrocodone per dosage unit (Vicodin), cocaine, methamphetamine,
methadone, hydromorphone (Deluded), meperidine (Demerol), oxycodone
(OxyContin), fentanyl, Dexedrine, Adderall, and Ritalin
DEA description of scheduled drugs - ANSWER - Drugs, substances, and
certain chemicals used to make drugs are classified into five (5) distinct
categories or schedules depending upon the drug's acceptable medical use
and the drug's abuse or dependency potential. The abuse rate is a
determinate factor in the scheduling of the drug; for example, Schedule I
drugs have a high potential for abuse and the potential to create severe
psychological and/or physical dependence.
Treatment of chronic pain - ANSWER - Nonpharmacologic therapy and
nonopioid pharmacologic therapy are preferred for chronic pain.
Benefits > Risks
Establish goals
Start with immediate release meds
start with the lowest effective dose
eval within 1-4 wks.
What is methadone? - ANSWER - Nonpharmacologic therapy and
nonopioid pharmacologic therapy are preferred for chronic pain.
What is the black box warning for methadone? - ANSWER - Methadone
can cause life-threatening QT prolongation and severe respiratory
depression. Because of the long half-life of methadone, it should be
prescribed only by health care providers with special training in chronic
pain management.
pg. 2
,factors for substance abuse - ANSWER - Drug related: availability, effect
and tolerability.
Predisposition: genetics, personality and psych
Environment: family, society, peer group, life events, stress
Benefit of using buprenorphine and naloxone - ANSWER -
Buprenorphine/naloxone combinations like Suboxone work in the body by
binding to opioid receptors, which help regulate hormones, physical
movement, emotions, and pleasure.
Order of HTN medications typically prescribed - ANSWER - thiazide-type
diuretic
calcium channel blocker (CCB)
angiotensin-converting enzyme inhibitor (ACEI)
angiotensin receptor blocker (ARB).
What is the best antihypertensive for someone with diabetes? - ANSWER -
ACEIs, ARBs, CCBs, and diuretics (in low doses).
best HTN med for pregnancy? - ANSWER - labetalol and methyldopa
What hen meds are contraindicated in pregnancy? - ANSWER - ACEIs,
ARBs, and DRIs,
Clonidine - ANSWER - site of action: brainstem
Suppression of sympathetic outflow decreases sympathetic stimulation of
the heart and blood vessels.
pg. 3
, Mecamylamine - ANSWER - site of action: Sympathetic ganglia
Ganglionic blockade reduces sympathetic stimulation of the heart and
blood vessels.
Reserpine - ANSWER - site of action: Adrenergic nerve terminals
Reduced norepinephrine release decreases sympathetic stimulation of the
heart and blood vessels.
What meds do not work as well for African Americans? - ANSWER - n
contrast, monotherapy with β blockers or ACEIs is less effective in African
Americans than in Caucasians. Nonetheless, β blockers and ACEIs should
be used if they are strongly indicated for a comorbid condition
what to prescribe in response to fibrotic changes? - ANSWER -
Sacubitril/valsartan (Entresto).
Aldosterone Antagonists (Spiro lactone)
Direct Renin Inhibitors
β Blockers
effects of cardiac glycosides - ANSWER - Digoxin exerts a positive
inotropic action on the heart. That is, the drug increases the force of
ventricular contraction and can thereby increase cardiac output
what happens when digoxin and quinidine are combined? - ANSWER -
when quinidine is Coad ministered with digoxin, quinidine inhibition of P-gp
results in an increase in digoxin absorption and a reduction of digoxin
elimination,
pg. 4
