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1. A nursing student asks for clarification on Spontaneous mutation leads to resistance
the differences between the mechanisms of to only one antimicrobial agent
spontaneous mutation and conjugation in
acquired resistance of microbes.
Which statement is correct?
2. A patient receiving a cephalosporin devel- Discontinuing the cephalosporin and be-
ops a secondary intestinal infection caused ginning flagyl
by Clostridium difficile.
What is an appropriate treatment for this
patient?
3. A patient is diagnosed with a lung infection Amikacin
caused by Pseudomonas aeruginosa. The
culture and sensitivity report shows sensi- When resistance to gentamicin and to-
tivity to all aminoglycosides. The provider bramycin is common, amikacin is the drug
knows that the rate of resistance to gentam- of choice for the initial treatment of amino-
icin is common in this hospital. glycoside-sensitive infections
Which medication should the provider be
expected to order?
4. A child with otitis media has had three ear "The bacteria have synthesized penicilli-
infections in the past year. The child has just nase"
completed a ten-day course of amoxicillin
with no improvement. The parent asks the Beta-lactamases are enzymes that cleave
provider why this drug is not working be- the beta-lactam ring and render the PCN
cause it has worked in the past. inactive (amoxicillin)
What should the provider tell the patient?
Pt will need to start augmentin
5. A patient who is taking acetaminophen It has minimal effects at peripheral sites
for pain wants to know why it does
not cause gastrointestinal upset as other Tylenol central effects
, WGU D116 Unit 8 OA Review
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over-the-counter pain medications do.
Which property of acetaminophen is the NSAIDs peripheral effects
most likely explanation for this?
6. A patient who has arthritis has been taking Prescribing an antiulcer medication
ibuprofen and a glucocorticoid medication.
The patient reports having tarry stools but Glucocorticoid therapy, especially when
denies gastric pain. combined with NSAIDs, can increase the
Which action by the provider is correct? risk of gastric ulcer and possibly bleeding
7. A patient will begin taking hydroxychloro- An eye exam is necessary at the beginning
quine for rheumatoid arthritis. The patient of therapy with this drug
is currently taking high-dose NSAIDs and
methotrexate. Can cause retinal damage - eye exam at
What should the patient be taught about the onset of treatment as well as every 6
hydroxychloroquine? months during treatment
8. A patient with gout who has increasingly "You will take both drugs initially and then
frequent acute gouty attacks will begin re- stop taking colchicine"
ceiving allopurinol and colchicine.
Which statement should be included when Colchicine is used for prophylaxis when
teaching the patient about this drug regi- urate-lowering drugs (allopurinal) are ini-
men? tiated because gouty episodes often in-
crease during this time.
9. A postmenopausal patient develops osteo- Raloxifene
porosis. The patient asks the provider about
medications to treat this condition. The Can preserve bone mineral density while
provider learns that the patient has a family protecting against breast and endometrial
history of breast cancer. cancers
Which medication should the provider dis-
cuss with the patient?