NBDHE (Topic nbdhe)inquiries and
responses,mid-course examination,JAN-
2025.Edition 1
Aspirin - answer-Considered NSAID
Functions of aspirin - answer-Analgesia, anyipyretic, anti inflammatory
Mechanism of action aspirin and ibuprofen - answer-Inhibition of prostaglandin
synthesis
Side effects of aspirin and ibuprofen - answer-Interferes w blood clotting,
contraindicated with warfarin/ coumadin, gi irritation(less w ibuprofen)
Warfarin/coumadin - answer-Blood thinner
Antipyretic. - answer-Reduce fever
Toxicity AKA - answer-Salicylism
Acetaminophen - answer-Aka Tylenol, not NSAID
Functions of tylenol - answer-Antipyretic, analgesic, not antiinflammatory
Someone on Coumadin should take what analgesic - answer-Acetaminophen
After SRP what analgesic recommended - answer-Tylenol
Examples of opioids - answer-Heroin codeine morphine
Mechanism of action opioids - answer-Blocks pain receptors in brain without loss of
consciousness
Most common opioid given in dentistry - answer-Codeine
Antitussive - answer-Cough suppressant
Overdose of codeine - answer-Respiratory depression and death
Side effect of codeine - answer-Emesis
Opioid antagonist that treats opioid overdose - answer-Narcan
,Treatment of narcotic withdrawal/dependence - answer-Methadone
Pupil size for heroin user - answer-Pinpoint pupils
Pupil size cocaine uswr - answer-Dilated pupils
Best pain medication for heroin addicts - answer-NSAIDs
Ability to kill bacteria - answer-Bactericidal
Ability to inhibit or slow multiplication and growth of bacteria - answer-Bacteriostatic
Most commonly prescribed antibacterial in dental profession - answer-Penicillin
Which type of penicillin is preferred? VK or G - answer-VK because G is inactivated by
gastric cells in absorption
Amoxicillin or penicillin - answer-Amox because it is TID (3xday) rather than QID
Penicillin mechanism of action - answer-Destroys bacterial cell Wall causing lysis
Most common antibacterial to cause anaphylaxis - answer-Penicillin
Most common allergic rxn - answer-Rash
Penicillin given to pregnant women? - answer-Yes
Amoxicillin not effective against - answer-Penicillinase(beta lactamase). Only when in
conjunction with clauvanic acid
Tetracycline is - answer-Bacteriostatic
Mechanism of action tetracycline - answer-Inhibiting protein synthesis
Used in pregnancy tetra? - answer-No because tooth discoloration in early childhood
Tetra should not be used in conjunction with what - answer-Dairy, antacids, iron tablets
Used how in dental - answer-Concentrates in Gcf, used for NUG/NUP AND aggressive
perio
Nitromidazole - answer-Antibiotics effective against obligate anaerobes only
Should be avoided in conjunction with what - answer-Listerine mouthwash because of
alcohol
, How is tuberculosis spread - answer-Droplet aerosol
How many spears necessary to determine that someone no longer has tuberculosis -
answer-3 consecutive negatice
Antigen used to aid in diagnosis of TB exposure - answer-Purified protein derivative
Skin test that tests for tuberculosis - answer-Mantoux
When is reaction measurwd - answer-48-72 hrs
What are the antituberculosis agents - answer-RIPE rifampin Isoniazid puraxinamide
ethambutol
What are the anti fungal agents - answer-Nystatin topical, fluconazole systemic
Conditions needing premed - answer-Precious IE, artificial heart valves, prosthetic joint
within 2 yrs, any shunts not stents
Not allergic to penicillin prophylactic antibiotic premed - answer-Amoxicillin 2g 1 hr
before
Child 50mg/kg
Allergic to Penicillin - answer-Cephalexin 2g 30-60 before clindamyacin 600mg
azithromycin 500mg
Noninvasive procedures not needing premed - answer-Radiographs, sealants, block
injections, impressions, fluoride, any procedure with little bleeding
Maximum intensity of effect that can be produced by drug regardless of dose - answer-
Efficacy
Amount of drug needed to produce an effect - answer-Potency
Oral route or rectal route - answer-Enteral
Safest cheapest least expensive roufe - answer-Oral
1st pass effect - answer-Must first pass thru Hepatic portal circulation which can
inactivate some drugs
Routes other than Oral or rectal - answer-Parenteral
Most rapid drug response route - answer-Intravascular, route of choice for emergency
situations
responses,mid-course examination,JAN-
2025.Edition 1
Aspirin - answer-Considered NSAID
Functions of aspirin - answer-Analgesia, anyipyretic, anti inflammatory
Mechanism of action aspirin and ibuprofen - answer-Inhibition of prostaglandin
synthesis
Side effects of aspirin and ibuprofen - answer-Interferes w blood clotting,
contraindicated with warfarin/ coumadin, gi irritation(less w ibuprofen)
Warfarin/coumadin - answer-Blood thinner
Antipyretic. - answer-Reduce fever
Toxicity AKA - answer-Salicylism
Acetaminophen - answer-Aka Tylenol, not NSAID
Functions of tylenol - answer-Antipyretic, analgesic, not antiinflammatory
Someone on Coumadin should take what analgesic - answer-Acetaminophen
After SRP what analgesic recommended - answer-Tylenol
Examples of opioids - answer-Heroin codeine morphine
Mechanism of action opioids - answer-Blocks pain receptors in brain without loss of
consciousness
Most common opioid given in dentistry - answer-Codeine
Antitussive - answer-Cough suppressant
Overdose of codeine - answer-Respiratory depression and death
Side effect of codeine - answer-Emesis
Opioid antagonist that treats opioid overdose - answer-Narcan
,Treatment of narcotic withdrawal/dependence - answer-Methadone
Pupil size for heroin user - answer-Pinpoint pupils
Pupil size cocaine uswr - answer-Dilated pupils
Best pain medication for heroin addicts - answer-NSAIDs
Ability to kill bacteria - answer-Bactericidal
Ability to inhibit or slow multiplication and growth of bacteria - answer-Bacteriostatic
Most commonly prescribed antibacterial in dental profession - answer-Penicillin
Which type of penicillin is preferred? VK or G - answer-VK because G is inactivated by
gastric cells in absorption
Amoxicillin or penicillin - answer-Amox because it is TID (3xday) rather than QID
Penicillin mechanism of action - answer-Destroys bacterial cell Wall causing lysis
Most common antibacterial to cause anaphylaxis - answer-Penicillin
Most common allergic rxn - answer-Rash
Penicillin given to pregnant women? - answer-Yes
Amoxicillin not effective against - answer-Penicillinase(beta lactamase). Only when in
conjunction with clauvanic acid
Tetracycline is - answer-Bacteriostatic
Mechanism of action tetracycline - answer-Inhibiting protein synthesis
Used in pregnancy tetra? - answer-No because tooth discoloration in early childhood
Tetra should not be used in conjunction with what - answer-Dairy, antacids, iron tablets
Used how in dental - answer-Concentrates in Gcf, used for NUG/NUP AND aggressive
perio
Nitromidazole - answer-Antibiotics effective against obligate anaerobes only
Should be avoided in conjunction with what - answer-Listerine mouthwash because of
alcohol
, How is tuberculosis spread - answer-Droplet aerosol
How many spears necessary to determine that someone no longer has tuberculosis -
answer-3 consecutive negatice
Antigen used to aid in diagnosis of TB exposure - answer-Purified protein derivative
Skin test that tests for tuberculosis - answer-Mantoux
When is reaction measurwd - answer-48-72 hrs
What are the antituberculosis agents - answer-RIPE rifampin Isoniazid puraxinamide
ethambutol
What are the anti fungal agents - answer-Nystatin topical, fluconazole systemic
Conditions needing premed - answer-Precious IE, artificial heart valves, prosthetic joint
within 2 yrs, any shunts not stents
Not allergic to penicillin prophylactic antibiotic premed - answer-Amoxicillin 2g 1 hr
before
Child 50mg/kg
Allergic to Penicillin - answer-Cephalexin 2g 30-60 before clindamyacin 600mg
azithromycin 500mg
Noninvasive procedures not needing premed - answer-Radiographs, sealants, block
injections, impressions, fluoride, any procedure with little bleeding
Maximum intensity of effect that can be produced by drug regardless of dose - answer-
Efficacy
Amount of drug needed to produce an effect - answer-Potency
Oral route or rectal route - answer-Enteral
Safest cheapest least expensive roufe - answer-Oral
1st pass effect - answer-Must first pass thru Hepatic portal circulation which can
inactivate some drugs
Routes other than Oral or rectal - answer-Parenteral
Most rapid drug response route - answer-Intravascular, route of choice for emergency
situations
