in the Care of Older Adults, 3rd Edition
by Laurie Kennedy-Malone, Verified Chapters 1 - 23, Complete
,Answers at the end of the Chapter
Chapter 1: Changes with Aging
Multiple Choice
Identify the choice that best completes the statement or answers the question.
1. The major impact of the physiological changes that occur with aging is:
A. Reduced physiological reserve
B. Reduced homeostatic mechanisms
C. Impaired immunological response
D. All of the above
2. The strongest evidence regarding normal physiological aging is available through:
A. Randomized controlled clinical trials
B. Cross-sectional studies
C. Longitudinal studies
D. Case control studies
3. All of the following statements are true about laboratory
values in older adultsexcept:
A. Reference ranges are preferable
B. Abnormal findings are often due to physiological aging
C. Normal ranges may not be applicable for older adults
D. Reference values are not necessarily acceptable values
4. Biochemical individuality is best described as:
A. Each individual’s variation is often much greater than that of a larger group
B. The unique biochemical profile of a selected population
C. The truly “normal” individual—falling within average range
D. Each individual’s variation is often much smaller than that of a larger group
, 5. Polypharmacy is best described as taking:
A. More than nine medications per day
B. More than five medications per day
C. Even a single medication if there is not a clear indication for its use
D. When a drug is given to treat the side effect of another drug
6. Pharmacokinetic changes with aging is reflective of:
A. What the drug does to the body
B. What the body does to the drug
C. The effect at the site of action and the time and intensity of the drug
D. The side effects commonly associated with the drug
7. All the following statements are false about drug absorption except:
A. Antacids increase the bioavailability of digitalis
B. Gastric acidity decreases with age
C. Anticholinergics increase colonic motility
D. Underlying chronic disease has little impact on drug absorption
8. All of the following statements are true about drug distribution in the
elderly except:
A. Drugs distributed in water have lower concentration
, B. Drugs idistributed iin ifat ihave iless iintense, imore iprolonged ieffect
C. Drugs ihighly iprotein ibound ihave igreater ipotential ito icause ian iadverse idrug ireaction
D. The ifastest iway ito ideliver ia idrug ito ithe iaction isite iis iby iinhalation
ii i 9. i Men ihave ifaster iand imore iefficient ibiotransformation iof idrugs iand
this iis ithought itobe idue ito:
A. Less iobesity irates ithan iwomen
B. Prostate ienlargement
C. Testosterone
D. Less iestrogen ithan iwomen
i i 10. i The icytochrome ip isystem iinvolves ienzymes ithat iare igenerally:
A. Inhibited iby idrugs
B. Induced iby idrugs
C. Inhibited ior iinduced iby idrugs
D. Associated iwith idecreased iliver iperfusion
i i 11. i A istatement i not ishown ito ibe itrue iabout i pharmacodynamics
i changesiwith iaging iis:
A. Decreased isensitivity ito ioral ianticoagulants
B. Enhanced isensitivity ito icentral inervous isystem idrugs
C. Drug iresponsiveness ican ibe iinfluenced iby ipatient iactivity ilevel
D. There iis ia idecreased isensitivity ito ibeta iblockers