, TIETZ CLINICAL CHEMISTRY EXAM QUESTIONS WITH
CORRECT ANSWERS
.1. A "subject-based" reference value is: a. obtained from a group of
systematically defined reference individuals. b. the type of value referred
to when the term reference value is used with no qualifying words. c.
based on several samples collected over time in a single individual. d. a
random sample of all individuals in the parent population who fulfill the
selection criteria. - Answer-Answer: a. obtained from a group of
systematically defined reference individuals.
.1. A nonspecific response to inflammation that includes elevation of
certain plasma proteins and decrease of others due to cytokine production
is referred to as a(n): a. Cytokine response. b. Acute-phase response. c.
Reduction reaction. d. Allergic reaction. - Answer-Answer: b. Acute-phase
response.
.1. Are the results obtained from a point-of-care test (POC) device
qualitative, quantitative, or semi-quantitative, or can they be all of these?
a. Qualitative only b. Quantitative only c. Semi-quantitative only d. All of
the above result types can be obtained from a point-of-care test device. -
Answer-Answer: d. All of the above result types can be obtained from a
point-of-care test device.
,.1. Ion-selective electrodes measure electrical potential difference across a
membrane using the principles of: a. Coulometry. b. Potentiometry. c.
Amperometry. d. Conductivity. - Answer-Answer: b. Potentiometry.
.1. Meta-analysis: a. is a statistical technique that compares results from
various studies. b. is an extensive and explicit strategy that is used to find
all studies (published or unpublished) pertaining to a single assay. c.
includes the quality and the quantity of the health outcome. d. is a tool
used to facilitate implementation of lessons from primary studies and
systematic reviews. - Answer-Answer: b. is an extensive and explicit
strategy that is used to find all studies (published or unpublished)
pertaining to a single assay.
.1. One aspect of universal precautions and an OSHA requirement involves
the provision of personal protective equipment (PPE) to laboratory
employees. PPE includes (but is not limited to) which of the following? a.
Gloves only. b. Gloves and a lab coat only. c. Gloves, eye protection, and a
lab coat. d. Gloves, eye protection, a lab coat, and special footwear. -
Answer-Answer: c. Gloves, eye protection, and a lab coat.
.1. Protein tumor markers found both in normal fetal tissue and in certain
tumors are referred to as: a. Embryonic proteins. b. Tumor-associated
antigens. c. Oncogenes. d. Oncofetal antigens. - Answer-Answer: d.
Oncofetal antigens.
.1. The clinical laboratory discipline that is used most often to assess
, inherited disease through the study of the constitutive genome is: a.
transfusion services. b. clinical chemistry. c. molecular diagnostics. d.
hematology. - Answer-Answer: c. molecular diagnostics.
.1. The component of an immunoassay that determines the analytical
sensitivity and specificity of the reaction is the: a. labeled antigen. b.
antigen. c. immunochemical label. d. antibody. - Answer-Answer: d.
antibody.
.1. The enzyme that demonstrates the highest serum activity in
intrahepatic biliary obstruction and is also elevated in primary liver
neoplasm is: a. Alkaline phosphatase (ALP). b. Creatine kinase (CK). c.
Amylase (AMY). d. γ-glutamyl transferase (GGT). - Answer-Answer: d. γ-
glutamyl transferase (GGT).
.1. The isoelectric point of an amino acid or protein is defined as the: a.
Ability of the amino acid or protein to carry both positive and negative
charges. b. pH at which the amino acid or protein has a negative charge. c.
pH at which a molecule has no net charge. d. Point on an electrophoretic
gel at which that specific protein migrates. - Answer-Answer: c. pH at
which a molecule has no net charge.
.1. The Michaelis-Menten constant is: a. Vmax. b. Km. c. 1/v. d. [S]. -
Answer-Answer: b. Km.
CORRECT ANSWERS
.1. A "subject-based" reference value is: a. obtained from a group of
systematically defined reference individuals. b. the type of value referred
to when the term reference value is used with no qualifying words. c.
based on several samples collected over time in a single individual. d. a
random sample of all individuals in the parent population who fulfill the
selection criteria. - Answer-Answer: a. obtained from a group of
systematically defined reference individuals.
.1. A nonspecific response to inflammation that includes elevation of
certain plasma proteins and decrease of others due to cytokine production
is referred to as a(n): a. Cytokine response. b. Acute-phase response. c.
Reduction reaction. d. Allergic reaction. - Answer-Answer: b. Acute-phase
response.
.1. Are the results obtained from a point-of-care test (POC) device
qualitative, quantitative, or semi-quantitative, or can they be all of these?
a. Qualitative only b. Quantitative only c. Semi-quantitative only d. All of
the above result types can be obtained from a point-of-care test device. -
Answer-Answer: d. All of the above result types can be obtained from a
point-of-care test device.
,.1. Ion-selective electrodes measure electrical potential difference across a
membrane using the principles of: a. Coulometry. b. Potentiometry. c.
Amperometry. d. Conductivity. - Answer-Answer: b. Potentiometry.
.1. Meta-analysis: a. is a statistical technique that compares results from
various studies. b. is an extensive and explicit strategy that is used to find
all studies (published or unpublished) pertaining to a single assay. c.
includes the quality and the quantity of the health outcome. d. is a tool
used to facilitate implementation of lessons from primary studies and
systematic reviews. - Answer-Answer: b. is an extensive and explicit
strategy that is used to find all studies (published or unpublished)
pertaining to a single assay.
.1. One aspect of universal precautions and an OSHA requirement involves
the provision of personal protective equipment (PPE) to laboratory
employees. PPE includes (but is not limited to) which of the following? a.
Gloves only. b. Gloves and a lab coat only. c. Gloves, eye protection, and a
lab coat. d. Gloves, eye protection, a lab coat, and special footwear. -
Answer-Answer: c. Gloves, eye protection, and a lab coat.
.1. Protein tumor markers found both in normal fetal tissue and in certain
tumors are referred to as: a. Embryonic proteins. b. Tumor-associated
antigens. c. Oncogenes. d. Oncofetal antigens. - Answer-Answer: d.
Oncofetal antigens.
.1. The clinical laboratory discipline that is used most often to assess
, inherited disease through the study of the constitutive genome is: a.
transfusion services. b. clinical chemistry. c. molecular diagnostics. d.
hematology. - Answer-Answer: c. molecular diagnostics.
.1. The component of an immunoassay that determines the analytical
sensitivity and specificity of the reaction is the: a. labeled antigen. b.
antigen. c. immunochemical label. d. antibody. - Answer-Answer: d.
antibody.
.1. The enzyme that demonstrates the highest serum activity in
intrahepatic biliary obstruction and is also elevated in primary liver
neoplasm is: a. Alkaline phosphatase (ALP). b. Creatine kinase (CK). c.
Amylase (AMY). d. γ-glutamyl transferase (GGT). - Answer-Answer: d. γ-
glutamyl transferase (GGT).
.1. The isoelectric point of an amino acid or protein is defined as the: a.
Ability of the amino acid or protein to carry both positive and negative
charges. b. pH at which the amino acid or protein has a negative charge. c.
pH at which a molecule has no net charge. d. Point on an electrophoretic
gel at which that specific protein migrates. - Answer-Answer: c. pH at
which a molecule has no net charge.
.1. The Michaelis-Menten constant is: a. Vmax. b. Km. c. 1/v. d. [S]. -
Answer-Answer: b. Km.
