Pharmacology: Exam 1 Quizzes UPDATED
ACTUAL Exam Questions and CORRECT
Answers
The study of how the body deals with drug in terms of the way the drug is absorbed, distributed,
and eliminated is known as - CORRECT ANSWER - pharmacokinetics
During drug testing and approval, the drug is usually tested in a relatively small sample (200-300
people) with a specific disease or pathologic condition during which phases of clinical trials? -
CORRECT ANSWER - phase 2 clinical trials
when 2 drugs are compared, the drug that requires a lower dosage to produce the same effect as a
higher dose of the second drug is said to - CORRECT ANSWER - be more potent
All the following are parenteral routes of drug administration EXCEPT which route? options=
inhalation, transdermal, oral, injection - CORRECT ANSWER - oral
The ____ effect occurs when drugs are transported initially to the liver where a significant
amount of the drug may be metabolized and destroyed before the drug reaches its primary site of
action - CORRECT ANSWER - first pass
The extent to which a drug reaches the systemic circulation is referred to as - CORRECT
ANSWER - bioavailability
The primary site for drug storage in the body is... - CORRECT ANSWER - adipose tissue
biotransformation usually results in an altered version of the original compound known as -
CORRECT ANSWER - a metabolite
the primary location of drug metabolism (biotransformation) is the... - CORRECT
ANSWER - liver
, drugs and their metabolites are excreted from the body primarily by... - CORRECT
ANSWER - the kidneys
When general anesthetics are administered by the inhalation route, a major advantage is they... -
CORRECT ANSWER - permit better control over the level of anesthesia
Local anesthetics are sometimes used to treat complex regional pain syndrome (CRPS), known
also as reflex sympathetic dystrophy syndrome (RSDS), by administering the drug... -
CORRECT ANSWER - near the sympathetic chain ganglia that innervate the affected limb
Local anesthetics inhibit action potential propagation along neuronal axons by blocking the
opening of ____ channels. - CORRECT ANSWER - sodium
Anti-seizure drugs have an effect on all neurons in the brain. (true or false?) - CORRECT
ANSWER - False. only hyper-excitable neurons are impacted
anti-seizure drugs work by increasing what? - CORRECT ANSWER - increasing GABA
inhibition
which of the following side effects of anti-seizure medications warrant immediate referral to a
physician? - CORRECT ANSWER - severe fatigue
2nd generation anti-seizure drugs have better pharmacokinetics than 1st gen. (true or false?) -
CORRECT ANSWER - true
One post-operative complication from general anesthesia that complicates rehabilitation is... -
CORRECT ANSWER - decline in cognition and attention
Which of the following anti-seizure drugs are also used to treat neuropathic pain? - CORRECT
ANSWER - Gabapentin
ACTUAL Exam Questions and CORRECT
Answers
The study of how the body deals with drug in terms of the way the drug is absorbed, distributed,
and eliminated is known as - CORRECT ANSWER - pharmacokinetics
During drug testing and approval, the drug is usually tested in a relatively small sample (200-300
people) with a specific disease or pathologic condition during which phases of clinical trials? -
CORRECT ANSWER - phase 2 clinical trials
when 2 drugs are compared, the drug that requires a lower dosage to produce the same effect as a
higher dose of the second drug is said to - CORRECT ANSWER - be more potent
All the following are parenteral routes of drug administration EXCEPT which route? options=
inhalation, transdermal, oral, injection - CORRECT ANSWER - oral
The ____ effect occurs when drugs are transported initially to the liver where a significant
amount of the drug may be metabolized and destroyed before the drug reaches its primary site of
action - CORRECT ANSWER - first pass
The extent to which a drug reaches the systemic circulation is referred to as - CORRECT
ANSWER - bioavailability
The primary site for drug storage in the body is... - CORRECT ANSWER - adipose tissue
biotransformation usually results in an altered version of the original compound known as -
CORRECT ANSWER - a metabolite
the primary location of drug metabolism (biotransformation) is the... - CORRECT
ANSWER - liver
, drugs and their metabolites are excreted from the body primarily by... - CORRECT
ANSWER - the kidneys
When general anesthetics are administered by the inhalation route, a major advantage is they... -
CORRECT ANSWER - permit better control over the level of anesthesia
Local anesthetics are sometimes used to treat complex regional pain syndrome (CRPS), known
also as reflex sympathetic dystrophy syndrome (RSDS), by administering the drug... -
CORRECT ANSWER - near the sympathetic chain ganglia that innervate the affected limb
Local anesthetics inhibit action potential propagation along neuronal axons by blocking the
opening of ____ channels. - CORRECT ANSWER - sodium
Anti-seizure drugs have an effect on all neurons in the brain. (true or false?) - CORRECT
ANSWER - False. only hyper-excitable neurons are impacted
anti-seizure drugs work by increasing what? - CORRECT ANSWER - increasing GABA
inhibition
which of the following side effects of anti-seizure medications warrant immediate referral to a
physician? - CORRECT ANSWER - severe fatigue
2nd generation anti-seizure drugs have better pharmacokinetics than 1st gen. (true or false?) -
CORRECT ANSWER - true
One post-operative complication from general anesthesia that complicates rehabilitation is... -
CORRECT ANSWER - decline in cognition and attention
Which of the following anti-seizure drugs are also used to treat neuropathic pain? - CORRECT
ANSWER - Gabapentin
