Pharmacology Exam 1 Study guide
UPDATED ACTUAL Exam Questions and
CORRECT Answers
What is a Half-Life? - CORRECT ANSWER - is the amount of time it takes after
absorption for 1/2 of the drugs concentration to be eliminated.
How does a half-life impact drug dosing? - CORRECT ANSWER - if the drugs 1/2 life is
36 hours they will only be taking it once a day. So its lasting effect in the body determines how
many times a person would take it.
What is protein binding? - CORRECT ANSWER - The ability of proteins to form bonds
with other substances, and most commonly refers to the bonding of drugs to these molecules in
blood plasma, red blood cells, other components of the blood and to tissue membranes.
How does protein binding effect drug absorption and dosing? - CORRECT ANSWER -
Drug dose is prescribed according to the percentage in which the drug binds to protein. It effects
drug absorption by what is put together if two highly protein bond drugs are together they will
cause toxicity.
What is Bioavailablity? - CORRECT ANSWER - is the percentage of a medication that
actually returns to the blood as an active metabolite.
How does bioavailablity effect drug dosing and and absorption? - CORRECT ANSWER -
By the amount of active drug in the system. Plus depending on route given it can cause toxicity
What is Hepatic first pass? - CORRECT ANSWER - In which the medication in the blood
stream are taken 1st the the liver, the dug may then be metabolized into an inactive form and
excreted, then reduces the amount of active drug.
How does "first pass" Effect drug dosing and absorption? - CORRECT ANSWER -
because not all drugs pass through the liver.
, What is Pinocytosis? - CORRECT ANSWER - Is when cells carry a drug across their
membrane by engulfing the drug particles. SO the cellular membrane engulfs drug particles.
What are Peak drug level, what is it used for? - CORRECT ANSWER - Peak is the highest
plasma concentration of the drug at the specific time. The peak indicates the rate of absorption.
What is the trough drug level, what is it used for? - CORRECT ANSWER - is the lowest
plasma concentration of a drug, it also measures the rate at which the drug is eliminated.
When do you obtain peak and trough levels? - CORRECT ANSWER - Trough levels are
drawn immediately before the next dose. blood samples are collected to assess these levels and
requested for drugs that can potentially be toxic.
What causes drug doses to be increased? - CORRECT ANSWER - The patient will effect
dosing, because not every person handles drugs the same. Then some drugs have a higher
efficacy.
What causes drug doses to be decreased? - CORRECT ANSWER - The patient, the type of
drug, and the cause and effect wanted out of the drug.
What is drug accumulation? - CORRECT ANSWER - increasing blood or tissue drug
levels over time.
What are the signs and symptoms of drug accumulation? - CORRECT ANSWER - ...
What is absorption? - CORRECT ANSWER - it is the movement of drug particles from
the GI tract to the body fluids.
How does absorption effect dosing? - CORRECT ANSWER - It effects dosing because
depending on the drug the different ways it can be adsorbed will either be slower or faster.
UPDATED ACTUAL Exam Questions and
CORRECT Answers
What is a Half-Life? - CORRECT ANSWER - is the amount of time it takes after
absorption for 1/2 of the drugs concentration to be eliminated.
How does a half-life impact drug dosing? - CORRECT ANSWER - if the drugs 1/2 life is
36 hours they will only be taking it once a day. So its lasting effect in the body determines how
many times a person would take it.
What is protein binding? - CORRECT ANSWER - The ability of proteins to form bonds
with other substances, and most commonly refers to the bonding of drugs to these molecules in
blood plasma, red blood cells, other components of the blood and to tissue membranes.
How does protein binding effect drug absorption and dosing? - CORRECT ANSWER -
Drug dose is prescribed according to the percentage in which the drug binds to protein. It effects
drug absorption by what is put together if two highly protein bond drugs are together they will
cause toxicity.
What is Bioavailablity? - CORRECT ANSWER - is the percentage of a medication that
actually returns to the blood as an active metabolite.
How does bioavailablity effect drug dosing and and absorption? - CORRECT ANSWER -
By the amount of active drug in the system. Plus depending on route given it can cause toxicity
What is Hepatic first pass? - CORRECT ANSWER - In which the medication in the blood
stream are taken 1st the the liver, the dug may then be metabolized into an inactive form and
excreted, then reduces the amount of active drug.
How does "first pass" Effect drug dosing and absorption? - CORRECT ANSWER -
because not all drugs pass through the liver.
, What is Pinocytosis? - CORRECT ANSWER - Is when cells carry a drug across their
membrane by engulfing the drug particles. SO the cellular membrane engulfs drug particles.
What are Peak drug level, what is it used for? - CORRECT ANSWER - Peak is the highest
plasma concentration of the drug at the specific time. The peak indicates the rate of absorption.
What is the trough drug level, what is it used for? - CORRECT ANSWER - is the lowest
plasma concentration of a drug, it also measures the rate at which the drug is eliminated.
When do you obtain peak and trough levels? - CORRECT ANSWER - Trough levels are
drawn immediately before the next dose. blood samples are collected to assess these levels and
requested for drugs that can potentially be toxic.
What causes drug doses to be increased? - CORRECT ANSWER - The patient will effect
dosing, because not every person handles drugs the same. Then some drugs have a higher
efficacy.
What causes drug doses to be decreased? - CORRECT ANSWER - The patient, the type of
drug, and the cause and effect wanted out of the drug.
What is drug accumulation? - CORRECT ANSWER - increasing blood or tissue drug
levels over time.
What are the signs and symptoms of drug accumulation? - CORRECT ANSWER - ...
What is absorption? - CORRECT ANSWER - it is the movement of drug particles from
the GI tract to the body fluids.
How does absorption effect dosing? - CORRECT ANSWER - It effects dosing because
depending on the drug the different ways it can be adsorbed will either be slower or faster.
