UPDATED: WGU: D027: Advanced
Pathopharmacological Foundations 2025|Actual
Exam Set Questions And Verified Answers
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- Brain shrinks dramatically; nerve cell death and
What are some physical tissue loss
changes from Alzheimer's - Cardinal signs: plaques (abnormal clusters of
dementia? protein fragments) and tangles (twisted strands of
another protein)
- There is no cure, but there are pharmacological
How is Alzheimer's and non-pharmacological treatments
treated? - Cholinesterase inhibitors
- Memantine (namenda)
- To treat symptoms related to memory, thinking,
What are cholinesterase
language, judgment, and other processes
inhibitors prescribed for?
- Helps delay or slow the worsening of symptoms
- Prevent the breakdown of acetylcholine, a
What does chemical messenger that is important for learning
cholinesterase inhibitors and memory
do? - Supports communication among nerve cells by
keeping the acetylcholine high
What are some - Donepezil (aricept)
commonly prescribed - Galantamine (razadyne)
cholinesterase inhibitors? - Rivastigmine (exeleon)
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, 1/23/25, 6:39 PM UPDATED: WGU: D027: Advanced Pathopharmacological Foundations 2025|Actual Exam Set Questions And Verified Answer…
Which cholinesterase - Donepezil (aricept)
inhibitor can be used for
all stages of Alzheimer's?
Which cholinesterase - Galantamine (razadyne)
inhibitor can be used for - Rivastigmine (exeleon)
mild-to-moderate stages
of Alzheimer's?
Which cholinesterase - Rivastigmine (exeleon)
inhibitor can be used for
mild-to-moderate
Alzheimer's and
Parkinson's?
What medication - Memantine (namenda) and donepezil (aricept)
combination is used to
treat moderate-to-severe
Alzheimer's?
- Prescribed to improve memory, attention, reason,
What is memantine language, and the ability to perform simple tasks
(namenda) used for? - Can be used alone or with other Alzheimer's
disease treatments
- Regulates the activity of glutamate, a chemical
involved in information processing, storage, and
How does memantine
retrieval
(namenda) work?
- Improves mental functioning and ability to perform
daily activities for some people
What is the difference in - Cholinesterase inhibitors prevent the breakdown
MOA between of acetylcholine, whereas memantine (namenda)
cholinesterase inhibitors regulates the activity of glutamate
and memantine
(namenda)?
- Also known as cerebellum attacks
- Degenerative disease of the nervous system
What is ataxia? - Many symptoms mimic those of being drunk (i.e.
slurred speech, stumbling, falling, and
incoordination)
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