Midterm Exam: NU664C Family Psychiatric Mental Health Study Guide with complete solution| Latest 2025/2026 Update- Regis.

Midterm Exam: NU664C Family Psychiatric i,- i,- i,- i,- i,-




Mental Health Study Guide with complete i,- i,- i,- i,- i,- i,-




solution| Latest 2025/2026 Update- Regis. i,- i,- i,- i,-




Know which antipsychotics have specific instructions for
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minimum food intake or diet restrictions. Geodon because
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food affects the absorption of the drug.
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Lurasidone - Latuda i,- i,-




Know an alternative atypical antipsychotic for a patient who has
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developed diabetes and has a significant weight gain from i,- i,- i,- i,- i,- i,- i,- i,- i,-



treatment with olanzapine. Abilify or Geodon, or Lurasidone
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(Latuda)
Because they are weight neutral or causes minimal weight gain.
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Know whether a patient is demonstrating efficacy to clozapine
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500 mg/day if this week's granulocyte count is less than 500mm3.
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What is the most appropriate recommendation for drug therapy?
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Stop the drug, because of the risk of agranulocytosis and
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patient can be infected. i,- i,- i,-




The most appropriate recommendation for drug therapy is to
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repeat CBC weekly. i,- i,-




> 1500, watch carefully if is at 1000
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,Know the common effects of smoking along with antipsychotic
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drug therapy such as olanzapine.
i,- Smoking reduces the level i,- i,- i,- i,-i,- i,- i,- i,- i,- i,-



of Olanzapine because of its metabolism at CYP450 enzyme.
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Be able to describe three positive symptoms and three negative
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symptoms of schizophrenia. Positive symptoms-Delusions,
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Hallucinations, Ideas of reference, Catatonic, Disorganized i,- i,- i,- i,- i,- i,-



speech, thinking or behavior i,- i,- i,-




Negative symptoms-Flat affect, Asocial, Monotone, Anhedonia,
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Avolition, Isolation, Poverty of Speech, Decreased self-care
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Know the route of administration for newer agent asenapine
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(Saphris) and what instructions should be given to the patient
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regarding administration. Route- Sublingual i,- i,-i,- i,- i,-




Not to eat or drink for 10 minutes after medication administration
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Not to swallow or chew the capsule.
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Asenapine is an atypical antipsychotic (serotonin-dopamine i,- i,- i,- i,- i,- i,-



antagonist, as a mood stabilizer). Asenapine is not absorbed afteri,- i,- i,- i,- i,- i,- i,- i,- i,- i,-



swallowing (less than 2% bioavailable orally) and thus must be i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-



administered sublingually (35% bioavailable), as swallowing i,- i,- i,- i,- i,- i,-



would render asenapine inactive.
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Patients should be instructed to place the tablet under the
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tongue and allow it to dissolve completely, which will occur in
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, seconds; tablet should not be divided, crushed, chewed, or
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swallowed.
Patients may not eat or drink for 10 minutes following sublingual
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administration so that the drug in the oral cavity can be absorbed i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-



locally and not washed into the stomach (where it would not be
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absorbed).
Due to rapid onset of action, can be used as a rapid acting "prn"
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or "as needed" dose for agitation or transient worsening of
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psychosis or mania instead of an injection. i,- i,- i,- i,- i,- i,-




Treatment should be suspended if absolute neutrophil count falls
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below 1,000/mm3. i,-




Know and describe the top atypical antipsychotic with greatest
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incidence of prolonged QTc interval. Ziprasidone (Geodon).
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Normal QTc =450. i,- i,-




>470, Call Cardiologist
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>500, stop all meds.i,- i,- i,-




Ziprasidone (Geodon) has been associated with a dose-related i,- i,- i,- i,- i,- i,- i,- i,-



prolongation of the QTc i,- i,- i,-




QTc interval prolongation is greatest with ziprasidone and least
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with olanzapine.
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Ziprasidone (Geodon) an atypical antipsychotic (serotonin- i,- i,- i,- i,- i,-



dopamine antagonist; second-generation antipsychotic; also a
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mood stabilizer. i,-