Fundamentals of Chemotherapy
Fundamentals
(ONS) Study
of Chemotherapy
Guide _Fundamentals
Oncology
(ONS)Nursing
Study
of Chemotherapy
Guide
& Drug_Therapy
Oncology
(ONS)
Review.pdf
Nursing
Study Guide
& Drug_Therapy
Oncology
Review.pdf
Nursing & Drug Therapy Review.pdf
Fundamentals of Chemotherapy (ONS)
Study Guide | Oncology Nursing & Drug
Therapy Review
Guidehttps://www.stuvia.com/dashboard!@_)#*)(@$)($@*($@)($@*_
Fundamentals of Chemotherapy
Fundamentals
(ONS) Study
of Chemotherapy
Guide _Fundamentals
Oncology
(ONS)Nursing
Study
of Chemotherapy
Guide
& Drug_Therapy
Oncology
(ONS)
Review.pdf
Nursing
Study Guide
& Drug_Therapy
Oncology
Review.pdf
Nursing & Drug Therapy Review.pdf
,Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf
Terms in this set (48)
Alkylating Agents NONSPECIFIC
-Interferes with DNA replication in all phases of cell cycle (alkylation)
*Parenteral route available (by mouth)
Examples
-Busulfan
-Carboplatin
-Cyclophosphamide
-Ifosfamide
-Melphalan
-Oxaliplatin
Common Side effects: myleosuppression, N/V, neurotoxicity, and other
drug specific effects
GREAT RESOURCE** Chemocare.com
Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf
,Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf
Alkylating Agent: Cyclophosphamide I- AML, ALL, CML, CLL, Hodgkin and Non-Hodgkin lymphoma, breast and
ovarian cancer, myeloma, neuroblastoma, mycosis fungoides, and
retinoblastoma
MOA- cell cycle nonspecific; interferes with DNA replication by cross-
linking DNA strands and interferes with RNA transcription
Vesicant info- irritant
Admin- IV, PO, intraperitoneal
C/I- severe marrow depression, impaired renal and hepatic dysfunction
AE- Acute: nausea (give antiemetic), acute hemorrhagic cystitis (bleeding
from bladder; encourage hydration & frequent voiding). Serious: syndrome
of inappropriate antidiuretic hormone secretion, renal tubular necrosis,
second malignancies. Other: alopecia, skin rash, N/V, myelosuppression,
nasal congestion, HA, dizziness, pulmonary fibrosis, pneumonitis
Special consideration- IV hydration pre & post infusion to prevent
hemorrhagic cystitis; encourage oral fluids to 2L per day with oral doses.
Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf
, Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf
Monitoring parameters- CBC/differential, liver function tests, renal
function tests, chemistry profile, urinalysis
Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf
Fundamentals
(ONS) Study
of Chemotherapy
Guide _Fundamentals
Oncology
(ONS)Nursing
Study
of Chemotherapy
Guide
& Drug_Therapy
Oncology
(ONS)
Review.pdf
Nursing
Study Guide
& Drug_Therapy
Oncology
Review.pdf
Nursing & Drug Therapy Review.pdf
Fundamentals of Chemotherapy (ONS)
Study Guide | Oncology Nursing & Drug
Therapy Review
Guidehttps://www.stuvia.com/dashboard!@_)#*)(@$)($@*($@)($@*_
Fundamentals of Chemotherapy
Fundamentals
(ONS) Study
of Chemotherapy
Guide _Fundamentals
Oncology
(ONS)Nursing
Study
of Chemotherapy
Guide
& Drug_Therapy
Oncology
(ONS)
Review.pdf
Nursing
Study Guide
& Drug_Therapy
Oncology
Review.pdf
Nursing & Drug Therapy Review.pdf
,Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf
Terms in this set (48)
Alkylating Agents NONSPECIFIC
-Interferes with DNA replication in all phases of cell cycle (alkylation)
*Parenteral route available (by mouth)
Examples
-Busulfan
-Carboplatin
-Cyclophosphamide
-Ifosfamide
-Melphalan
-Oxaliplatin
Common Side effects: myleosuppression, N/V, neurotoxicity, and other
drug specific effects
GREAT RESOURCE** Chemocare.com
Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf
,Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf
Alkylating Agent: Cyclophosphamide I- AML, ALL, CML, CLL, Hodgkin and Non-Hodgkin lymphoma, breast and
ovarian cancer, myeloma, neuroblastoma, mycosis fungoides, and
retinoblastoma
MOA- cell cycle nonspecific; interferes with DNA replication by cross-
linking DNA strands and interferes with RNA transcription
Vesicant info- irritant
Admin- IV, PO, intraperitoneal
C/I- severe marrow depression, impaired renal and hepatic dysfunction
AE- Acute: nausea (give antiemetic), acute hemorrhagic cystitis (bleeding
from bladder; encourage hydration & frequent voiding). Serious: syndrome
of inappropriate antidiuretic hormone secretion, renal tubular necrosis,
second malignancies. Other: alopecia, skin rash, N/V, myelosuppression,
nasal congestion, HA, dizziness, pulmonary fibrosis, pneumonitis
Special consideration- IV hydration pre & post infusion to prevent
hemorrhagic cystitis; encourage oral fluids to 2L per day with oral doses.
Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf
, Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf
Monitoring parameters- CBC/differential, liver function tests, renal
function tests, chemistry profile, urinalysis
Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf Fundamentals of Chemotherapy ONS.pdf
