NSG 6005 Pharm Midterm Exam Study Guide
Set 2 | Latest 2023/2024 -
A patient's nutritional intake and lab work reflect hypoalbuminemia. This is critical
to prescribing because: - ANSWER>>Distribution of drugs to target tissue may be
affected
Class IC drugs are reserved for what type of arrhythmia - ANSWER>>severe
ventricular tachycardia
Class III drugs are effective in treating - ANSWER>>ventricular fibrillation
Half life of procainamide - ANSWER>>only short acting antiarrhythmic
antiarrhythmics are metabolized in the ____________ - ANSWER>>Liver
To treat or not to treat antiarrhythmic - ANSWER>>Antiarrhythmic drugs are
understood to be proarrhythmic, they can paradoxically correct one issue, but
then cause another lethal arrhythmia. Deciding not to treat may be a better
choice, especially in asymptomatic or minimally symptomatic patients
Drugs that have a significant first-pass effect: - ANSWER>>Are rapidly metabolized
by the liver and may have little if any desired action
The route of excretion of a volatile drug will be: - ANSWER>>The lungs
The point in time on the drug concentration curve that indicated the first sign of a
therapeutic effect is the: - ANSWER>>Onset of action
Factors that affect gastric drug absorption include: - ANSWER>>Lipid solubility of
the drug
,Which one of the following statements about bio availability is true? -
ANSWER>>Bio availability issues are especially important for drugs with narrow
therapeutic ranges or sustained release mechanisms.
Steady State is: - ANSWER>>When the amount of drug in the body remains
constant.
The time required for the amount of drug in the body to decrease by 50% is
called: - ANSWER>>Half-life
An advantage of prescribing a sublingual medication is that the medication is: -
ANSWER>>Absorbed rapidly
Drugs that use CYP 3A4 isoenzymes for metabolism may:
1. Induce the metabolism of another drug
2. Inhibit the metabolism of another drug
3. Both 1 and 2
4. Neither 1 nor 2 - ANSWER>>BOTH A and B
Induce the metabolism of another drug
Inhibit the metabolism of another drug
A nurse practitioner would prescribe the liquid form of ibuprofen for a six-year-
old because: - ANSWER>>A six year old may have problems with swallowing a pill.
The first step in the prescribing process according to the world health
organization is: - ANSWER>>diagnosing the patient's problem D
, Patient Education regarding prescribed medication includes: -
ANSWER>>Discussion of expected ADRs
Pharmacokinetic factors that affect prescribing include - ANSWER>>Bioavalability
Infants and young children are at higher risk of ADRs due to - ANSWER>>Lack of
safety and efficacy studies in the pediatric population
The elderly are at high risk of ADRs due to: - ANSWER>>Age related decrease in
renal function
The type of ADR that is the result of an unwanted but otherwise normal
pharmacological action of a drug given in the usual therapeutic doses is -
ANSWER>>Type A
A patient may develop neutropenia from using typical Silvadene for burns.
Neutropenia is: - ANSWER>>A cytoxic hypersensitivity reaction
The ACE inhibitor Lisionpril is a known teratogen. Teratogens cause Type ______
ADR. - ANSWER>>D
A twenty year old male recieved multiple fractures in a motor vehichle accident
that required significant amounts of opioid medication to treat his pain. He is at
risk for type ____ ADR when he no longer requires the opioids. - ANSWER>>E
Which of the following factors may adversely affect a patients adherence to a
therapeutic drug regimen - ANSWER>>Both A and B
Non-adherence is especially common in drugs that treat asymptomatic
conditions, such as hypertension. One way to reduce the likelihood of
nonadhereence to these drugs is to prescribe a drug that: - ANSWER>>Has a
tolerability profile with less of the adverse effects that are considered "irritating"
such as nausea and vomiting.
Set 2 | Latest 2023/2024 -
A patient's nutritional intake and lab work reflect hypoalbuminemia. This is critical
to prescribing because: - ANSWER>>Distribution of drugs to target tissue may be
affected
Class IC drugs are reserved for what type of arrhythmia - ANSWER>>severe
ventricular tachycardia
Class III drugs are effective in treating - ANSWER>>ventricular fibrillation
Half life of procainamide - ANSWER>>only short acting antiarrhythmic
antiarrhythmics are metabolized in the ____________ - ANSWER>>Liver
To treat or not to treat antiarrhythmic - ANSWER>>Antiarrhythmic drugs are
understood to be proarrhythmic, they can paradoxically correct one issue, but
then cause another lethal arrhythmia. Deciding not to treat may be a better
choice, especially in asymptomatic or minimally symptomatic patients
Drugs that have a significant first-pass effect: - ANSWER>>Are rapidly metabolized
by the liver and may have little if any desired action
The route of excretion of a volatile drug will be: - ANSWER>>The lungs
The point in time on the drug concentration curve that indicated the first sign of a
therapeutic effect is the: - ANSWER>>Onset of action
Factors that affect gastric drug absorption include: - ANSWER>>Lipid solubility of
the drug
,Which one of the following statements about bio availability is true? -
ANSWER>>Bio availability issues are especially important for drugs with narrow
therapeutic ranges or sustained release mechanisms.
Steady State is: - ANSWER>>When the amount of drug in the body remains
constant.
The time required for the amount of drug in the body to decrease by 50% is
called: - ANSWER>>Half-life
An advantage of prescribing a sublingual medication is that the medication is: -
ANSWER>>Absorbed rapidly
Drugs that use CYP 3A4 isoenzymes for metabolism may:
1. Induce the metabolism of another drug
2. Inhibit the metabolism of another drug
3. Both 1 and 2
4. Neither 1 nor 2 - ANSWER>>BOTH A and B
Induce the metabolism of another drug
Inhibit the metabolism of another drug
A nurse practitioner would prescribe the liquid form of ibuprofen for a six-year-
old because: - ANSWER>>A six year old may have problems with swallowing a pill.
The first step in the prescribing process according to the world health
organization is: - ANSWER>>diagnosing the patient's problem D
, Patient Education regarding prescribed medication includes: -
ANSWER>>Discussion of expected ADRs
Pharmacokinetic factors that affect prescribing include - ANSWER>>Bioavalability
Infants and young children are at higher risk of ADRs due to - ANSWER>>Lack of
safety and efficacy studies in the pediatric population
The elderly are at high risk of ADRs due to: - ANSWER>>Age related decrease in
renal function
The type of ADR that is the result of an unwanted but otherwise normal
pharmacological action of a drug given in the usual therapeutic doses is -
ANSWER>>Type A
A patient may develop neutropenia from using typical Silvadene for burns.
Neutropenia is: - ANSWER>>A cytoxic hypersensitivity reaction
The ACE inhibitor Lisionpril is a known teratogen. Teratogens cause Type ______
ADR. - ANSWER>>D
A twenty year old male recieved multiple fractures in a motor vehichle accident
that required significant amounts of opioid medication to treat his pain. He is at
risk for type ____ ADR when he no longer requires the opioids. - ANSWER>>E
Which of the following factors may adversely affect a patients adherence to a
therapeutic drug regimen - ANSWER>>Both A and B
Non-adherence is especially common in drugs that treat asymptomatic
conditions, such as hypertension. One way to reduce the likelihood of
nonadhereence to these drugs is to prescribe a drug that: - ANSWER>>Has a
tolerability profile with less of the adverse effects that are considered "irritating"
such as nausea and vomiting.
