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ABGC Boards - Final Review | Q&A Latest Update 2024/2025 | 100% PASS
Preview 4 out of 112 pages
ABGC Boards - Final Review | Q&A Latest Update 2024/2025 | 100% PASS Hereditary Breast and Ovarian Cancer - Answer -BRCA 1/2 Breast 50-87% Second primary tumor 50-64% BRCA 1: 20-45% BRCA 2: 10-30% BRCA 2: Male breast 6-10% Li-Fraumeni Syndrome - Answer --Sarcoma, breast, leukemia, adrenal and many others -May present in almost every way (ie all family members with same cancers or all with different) -Adrenocortical carcinoma considered pathognomonic -50% have some type by 30, 90% by age 60 -TP53 accounts for 70% of individuals Beckwith-Wiedemann - Answer -Overgrowth disorder in children, tongue, viscera, hemihyperplasia,
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