and answers with solutions 2025
Natural Menopause: - ANSWER A cessation of menstruation for at least 12 consecutive months, median
age 52
Perimenopause: - ANSWER Cycle irregularities and menopause symptoms: hot flashes, vaginal dryness,
decreased libido, dyspareunia; spans 2-8 years prior to last menstrual period.
Induced menopause - ANSWER -surgically (bilateral oophorectomy)
- chemotherapy or radiation
premature ovarian failure - ANSWER Occurs in women younger than age 40, temporary or permanent
loss of ovarian function associated with autoimmune and genetic disorders
Menopause Presentation: - ANSWER - Irregular menses
- hot flashes
- Skin/hair/nail changes
- painful intercourse
- decreased libido
- fatigue
- sleep disturbance
- Atrophic vaginitis: thin yellow discharge, pH >5.5, pruritis
- Decreased bone density
- dry skin
- forgetfulness
- anxiety
- headaches
- palpitations
, Menopause is a marked reduction in ovarian estrogen productions. This causes - - ANSWER low serum
estradiol and VMS
The predominant estrogen after menopause is - ANSWER estrone
Midlife Health Issues: - ANSWER - Cancer
- Osteoporosis
- Obesity
- CVD
- Type 2 DM
Cancer - ANSWER Most frequently diagnosed breast (30%), lung (13%), colon and rectum (8%),
pancreatic (8%)
Osteoporosis: Decreased bone mass; most common cause of morbidity in postmenopausal women
Screening starts at age 65 - ANSWER - Primary: aging slow decline in bone mass, menopause associated
estrogen deficiency triggers bone loss
- Secondary - response to medications (corticosteroids, anticonvulsants, methotrexate); chronic disease
state: hyperthyroidism, chronic liver disease, GI malabsorption
- Idiopathic - low bone density and fracture in young adults no cause identified.
Screening Bone Mineral Density (BMD) evaluated with x-ray DEXA scan. Women with low T scores and Z
scores are at risk for osteroporosis - ANSWER Z-scores: BMD compared to age, sex, and ethnicity
T-scores: Number of standard deviations that BMD is greater or less than a younger adult-gender
matched norm.