NUR 2060 PHARMACOLOGY FINAL EXAM REVIEW
2024/2025 STUDY QUESTIONS WITH CORRECT
ANSWERS TOP RATED | GUARANTEED PASS
I Wish You the Best in Your Studies and Exam Revision.
,What is tyramine, where is it found (food sources), and why do we care? - Answer>>> --
tyramine acts as a catecholamine releasing agent (epinephrine, norepinephrine and dopamine)
--tyramine-rich foods: yeast, cheese, aged fish/meat, figs, bananas, wine
--pts. taking MAO-I's should avoid tyramine-rich foods because it can cause a HTN crisis
What is vincristine (Oncovin) used to treat? Action? - Answer>>> --prevents cell division in "M"
phase
--minimal myelosuppression, toxic to peripheral nerves
**assess for numbness, tingling in fingers and toes, constipation, difficulty walking (ataxia)
--FATAL is given via intrathecally (via spinal cord)
What are the adverse effects of protease inhibitors? And give a drug example - Answer>>> --
lopinavir/ritonavir (Kaletra)
--ADRS: hyperglycemia, fat redistribution, hyperlipidemia, reduced bone density,
hepatotoxicity, increased bleeding, prolonged QT interval, drug interactions (CYP p450)
What is the lab goal for patients with HIV? - Answer>>> --higher CD4 (<200= AIDS)
--lower viral load
What are the onset, peak, and duration of the long duration insulin? - Answer>>> (insulin
glargine, insulin detemir)
--onset= 60-120 min
--peak= 12-24 (NO peak in glargine)
--duration= 18-24 hrs
What are the taxane drugs? What are they used for? ADRs? - Answer>>> --paclitaxel (Taxol)
--docetaxal (Taxotere)
--used for lung, ovarian, gastric, breast
--infuse SLOWLY
,--use H1 & H2 blockers BEFORE paclitaxel (Taxol) dose
--use dexamethasone BEFORE docetaxal (Taxotere)
What is asparaginase (Elspar) used for? Action? ADRs? - Answer>>> --used to treat acute
leukemias
--action is to deprive cells of essential amino acids needed to synthesis proteins
--ADRs: coagulation difficulties, injury to liver, pancreas & kidneys, CNS depression,
hypersensitivity, anaphylaxis
Why is dexamethasone used in adjunct to CA treatments? - Answer>>> --minimizes or manages
side effects such as N/V, fluid retention, allergic reactions, and anorexia
What are the signs and symptoms of hyperglycemia? - Answer>>> -drowsiness
-flushed, dry skin
-fruit-like breath odor
-frequent urination
-loss of appetite
-tiredness
-unusual thirst
What is leuprolide (Lupron) used to treat? Action? ADRs? - Answer>>> -Gonadotropin-
releasing hormone analog-
--used to treat prostate and breast CA
--action is to REDUCE production of androgens by testes and estrogen by ovaries
--ADRs: hot flashes, erectile dysfunction, decreased libido, gynecomastia
What is tamoxifen (Nolvadex) used to treat? Action? ADRs? - Answer>>> --most widely Rx
anticancer agent
--for treatment of breast cancer
--action is to bind to estrogen receptors in breast and block estradiol form binding
--ADRs: N/V, hot flashes, irregular menses, increased endometrial CA, DVTs & PE's
, **often used in combo w/ GnRH analog leuprolide to suppress ovarian estrogen production
What would low levels of albumin while taking a medication do in the body? - Answer>>> Low
levels of albumin would increase the level of that drug in the blood stream causing it to have a
more profound/harmful effect on the patient
What is important to know about pregnancy and drug administration? - Answer>>> --pregnant
women have higher rates of metabolism and excretion so may need to give higher dose
--pregnant women also have slower GI motility
What is peptic ulcer disease? - Answer>>> upper GI disorders, degrees of erosion of the gut
wall; an imbalance between mucosal defenses and aggressive factors
What are the major antibiotics used for H.pylori? - Answer>>> --amoxicillin (Amoxil)
--bismuth (Pepto bismol)
--metronidazole (Flagyl)
What is the action of histamine 2 receptor antagonists (H2 blockers)? - Answer>>> inhibits
gastric acid secretion
Give examples of histamine 2 receptor antagonists (H2 blockers). - Answer>>> "-dine"
--cimetidine (Tagamet)
--ranitidine (Zantac)
--famotidie (Pepcid)
What is important to note as a nurse when giving histamine 2 receptor antagonists (H2
blockers)? - Answer>>> --avoid antacids 1 hour before giving H2 blocker
--increased bleeding
--risk of pneumonia
--no smoking, ETOH, or NSAID usage
--elevate head of bed
What is the action of Proton Pump Inhibitors (PPI's)? - Answer>>> --suppress gastric acid
secretion (block enzyme needs dof R acid formation)
2024/2025 STUDY QUESTIONS WITH CORRECT
ANSWERS TOP RATED | GUARANTEED PASS
I Wish You the Best in Your Studies and Exam Revision.
,What is tyramine, where is it found (food sources), and why do we care? - Answer>>> --
tyramine acts as a catecholamine releasing agent (epinephrine, norepinephrine and dopamine)
--tyramine-rich foods: yeast, cheese, aged fish/meat, figs, bananas, wine
--pts. taking MAO-I's should avoid tyramine-rich foods because it can cause a HTN crisis
What is vincristine (Oncovin) used to treat? Action? - Answer>>> --prevents cell division in "M"
phase
--minimal myelosuppression, toxic to peripheral nerves
**assess for numbness, tingling in fingers and toes, constipation, difficulty walking (ataxia)
--FATAL is given via intrathecally (via spinal cord)
What are the adverse effects of protease inhibitors? And give a drug example - Answer>>> --
lopinavir/ritonavir (Kaletra)
--ADRS: hyperglycemia, fat redistribution, hyperlipidemia, reduced bone density,
hepatotoxicity, increased bleeding, prolonged QT interval, drug interactions (CYP p450)
What is the lab goal for patients with HIV? - Answer>>> --higher CD4 (<200= AIDS)
--lower viral load
What are the onset, peak, and duration of the long duration insulin? - Answer>>> (insulin
glargine, insulin detemir)
--onset= 60-120 min
--peak= 12-24 (NO peak in glargine)
--duration= 18-24 hrs
What are the taxane drugs? What are they used for? ADRs? - Answer>>> --paclitaxel (Taxol)
--docetaxal (Taxotere)
--used for lung, ovarian, gastric, breast
--infuse SLOWLY
,--use H1 & H2 blockers BEFORE paclitaxel (Taxol) dose
--use dexamethasone BEFORE docetaxal (Taxotere)
What is asparaginase (Elspar) used for? Action? ADRs? - Answer>>> --used to treat acute
leukemias
--action is to deprive cells of essential amino acids needed to synthesis proteins
--ADRs: coagulation difficulties, injury to liver, pancreas & kidneys, CNS depression,
hypersensitivity, anaphylaxis
Why is dexamethasone used in adjunct to CA treatments? - Answer>>> --minimizes or manages
side effects such as N/V, fluid retention, allergic reactions, and anorexia
What are the signs and symptoms of hyperglycemia? - Answer>>> -drowsiness
-flushed, dry skin
-fruit-like breath odor
-frequent urination
-loss of appetite
-tiredness
-unusual thirst
What is leuprolide (Lupron) used to treat? Action? ADRs? - Answer>>> -Gonadotropin-
releasing hormone analog-
--used to treat prostate and breast CA
--action is to REDUCE production of androgens by testes and estrogen by ovaries
--ADRs: hot flashes, erectile dysfunction, decreased libido, gynecomastia
What is tamoxifen (Nolvadex) used to treat? Action? ADRs? - Answer>>> --most widely Rx
anticancer agent
--for treatment of breast cancer
--action is to bind to estrogen receptors in breast and block estradiol form binding
--ADRs: N/V, hot flashes, irregular menses, increased endometrial CA, DVTs & PE's
, **often used in combo w/ GnRH analog leuprolide to suppress ovarian estrogen production
What would low levels of albumin while taking a medication do in the body? - Answer>>> Low
levels of albumin would increase the level of that drug in the blood stream causing it to have a
more profound/harmful effect on the patient
What is important to know about pregnancy and drug administration? - Answer>>> --pregnant
women have higher rates of metabolism and excretion so may need to give higher dose
--pregnant women also have slower GI motility
What is peptic ulcer disease? - Answer>>> upper GI disorders, degrees of erosion of the gut
wall; an imbalance between mucosal defenses and aggressive factors
What are the major antibiotics used for H.pylori? - Answer>>> --amoxicillin (Amoxil)
--bismuth (Pepto bismol)
--metronidazole (Flagyl)
What is the action of histamine 2 receptor antagonists (H2 blockers)? - Answer>>> inhibits
gastric acid secretion
Give examples of histamine 2 receptor antagonists (H2 blockers). - Answer>>> "-dine"
--cimetidine (Tagamet)
--ranitidine (Zantac)
--famotidie (Pepcid)
What is important to note as a nurse when giving histamine 2 receptor antagonists (H2
blockers)? - Answer>>> --avoid antacids 1 hour before giving H2 blocker
--increased bleeding
--risk of pneumonia
--no smoking, ETOH, or NSAID usage
--elevate head of bed
What is the action of Proton Pump Inhibitors (PPI's)? - Answer>>> --suppress gastric acid
secretion (block enzyme needs dof R acid formation)
