Biochem 301 Exam2 | Questions with 100%
Correct Answers| Verified-
ring
Disulfide bonds intracellularly and extracellularly - ✔✔-Disulfide bonds don't typically
exist intracellularly
-Exist outside the cell to maintain protein structure in the harsh external environment to
maintain protein structure
-Extracellular environment is oxidizing, resulting in disulfide bonds
Alpha helix structure - ✔✔-backbone atoms follow helical pathway
-held together by hydrogen bonds between every fourth carbon (i+3)
Beta sheet structure - ✔✔-formed using carbon backbone
-can be parallel or anti-parallel
Difference between alpha helix and beta sheet - ✔✔-alpha helix is formed from a
single chain of amino acids
-beta sheet is formed from several short contiguous amino acid chains placed side by
side
Anti-parallel vs. parallel beta sheet - ✔✔Must have longer loops for parallel structure
than anti-parallel structure
Ramachandran plot - ✔✔-only some of the phi, psi angle combinations occur (cluster
in certain regions)
, -sterics explain why only certain combinations occur (side chains may run into each
other in certain phi, psi angle combinations)
Motif - ✔✔some kind of reoccurring structure that combines certain secondary
structural sections
Surface vs. ribbon structure - ✔✔-surface: shows all components of the protein
(surface shapes)
-ribbon: shows mostly the backbone of the protein
3 types of tertiary protein structure - ✔✔1. all alpha helix
2. mixed alpha helix/beta sheet
3. all beta sheet
Quaternary protein structure - ✔✔-different parts fold independently then come
together
-alpha-helices cannot be extended through dimerization
Interface - ✔✔where 2 structures come together
Tertiary vs. quaternary protein structure - ✔✔-tertiary: independent sections folding
-quaternary: how those independent sections come together
3 most common transmembrane protein structures - ✔✔1. single alpha helix
2. multiple alpha helices in a bundle
3. beta barrel
Correct Answers| Verified-
ring
Disulfide bonds intracellularly and extracellularly - ✔✔-Disulfide bonds don't typically
exist intracellularly
-Exist outside the cell to maintain protein structure in the harsh external environment to
maintain protein structure
-Extracellular environment is oxidizing, resulting in disulfide bonds
Alpha helix structure - ✔✔-backbone atoms follow helical pathway
-held together by hydrogen bonds between every fourth carbon (i+3)
Beta sheet structure - ✔✔-formed using carbon backbone
-can be parallel or anti-parallel
Difference between alpha helix and beta sheet - ✔✔-alpha helix is formed from a
single chain of amino acids
-beta sheet is formed from several short contiguous amino acid chains placed side by
side
Anti-parallel vs. parallel beta sheet - ✔✔Must have longer loops for parallel structure
than anti-parallel structure
Ramachandran plot - ✔✔-only some of the phi, psi angle combinations occur (cluster
in certain regions)
, -sterics explain why only certain combinations occur (side chains may run into each
other in certain phi, psi angle combinations)
Motif - ✔✔some kind of reoccurring structure that combines certain secondary
structural sections
Surface vs. ribbon structure - ✔✔-surface: shows all components of the protein
(surface shapes)
-ribbon: shows mostly the backbone of the protein
3 types of tertiary protein structure - ✔✔1. all alpha helix
2. mixed alpha helix/beta sheet
3. all beta sheet
Quaternary protein structure - ✔✔-different parts fold independently then come
together
-alpha-helices cannot be extended through dimerization
Interface - ✔✔where 2 structures come together
Tertiary vs. quaternary protein structure - ✔✔-tertiary: independent sections folding
-quaternary: how those independent sections come together
3 most common transmembrane protein structures - ✔✔1. single alpha helix
2. multiple alpha helices in a bundle
3. beta barrel
