1. A nurse is preparing to administer a beta-blocker to a client with
hypertension. Which adverse effect should the nurse monitor for?
a) Tachycardia
b) Bradycardia
c) Increased cardiac output
d) Hyperkalemia
Answer: b) Bradycardia
Rationale: Beta-blockers decrease heart rate by blocking beta-adrenergic
receptors, leading to bradycardia.
2. A client with diabetes mellitus is prescribed prednisone. What effect should
the nurse monitor for?
a) Hypoglycemia
b) Hyperglycemia
c) Weight loss
d) Bradycardia
Answer: b) Hyperglycemia
Rationale: Prednisone is a corticosteroid that increases blood glucose levels by
promoting gluconeogenesis and decreasing insulin sensitivity.
3. A nurse is educating a client about taking levothyroxine. What should the
nurse include?
a) Take the medication with meals.
b) Take the medication at bedtime.
c) Take the medication on an empty stomach.
d) Take the medication with antacids.
Answer: c) Take the medication on an empty stomach.
Rationale: Levothyroxine absorption is optimal on an empty stomach, typically 30-
60 minutes before breakfast.
,4. Which laboratory value should be monitored in a client taking warfarin?
a) Hemoglobin
b) INR
c) Potassium
d) Creatinine
Answer: b) INR
Rationale: Warfarin effectiveness and safety are monitored using INR
(International Normalized Ratio) to assess clotting time.
5. A nurse is administering vancomycin IV. Which adverse effect should the nurse
be alert for?
a) Hepatotoxicity
b) Nephrotoxicity
c) Red man syndrome
d) Stevens-Johnson syndrome
Answer: c) Red man syndrome
Rationale: Rapid infusion of vancomycin can lead to flushing, hypotension, and
itching, collectively called red man syndrome.
6. A client is prescribed digoxin. Which finding indicates digoxin toxicity?
a) Tachycardia
b) Visual disturbances
c) Hypertension
d) Diarrhea
Answer: b) Visual disturbances
Rationale: Symptoms of digoxin toxicity include blurred or yellow-tinged vision,
fatigue, and gastrointestinal disturbances.
7. Which medication is used as the antidote for benzodiazepine overdose?
, a) Naloxone
b) Flumazenil
c) Protamine sulfate
d) Atropine
Answer: b) Flumazenil
Rationale: Flumazenil is a benzodiazepine antagonist that reverses sedation and
respiratory depression caused by benzodiazepines.
8. A client taking furosemide is at risk for which electrolyte imbalance?
a) Hyperkalemia
b) Hypokalemia
c) Hypernatremia
d) Hypercalcemia
Answer: b) Hypokalemia
Rationale: Furosemide is a loop diuretic that increases potassium excretion,
leading to hypokalemia.
9. A nurse is educating a client about nitroglycerin for chest pain. What should
the nurse include?
a) Take the medication only in the morning.
b) Store the medication in a warm, humid place.
c) Take up to three tablets, 5 minutes apart, for unrelieved chest pain.
d) Swallow the tablet with a full glass of water.
Answer: c) Take up to three tablets, 5 minutes apart, for unrelieved chest pain.
Rationale: Sublingual nitroglycerin should be taken as described for acute angina.
If pain persists, emergency care is needed.
10. What is a contraindication for administering metformin to a client?
a) History of liver failure
b) Current insulin therapy
hypertension. Which adverse effect should the nurse monitor for?
a) Tachycardia
b) Bradycardia
c) Increased cardiac output
d) Hyperkalemia
Answer: b) Bradycardia
Rationale: Beta-blockers decrease heart rate by blocking beta-adrenergic
receptors, leading to bradycardia.
2. A client with diabetes mellitus is prescribed prednisone. What effect should
the nurse monitor for?
a) Hypoglycemia
b) Hyperglycemia
c) Weight loss
d) Bradycardia
Answer: b) Hyperglycemia
Rationale: Prednisone is a corticosteroid that increases blood glucose levels by
promoting gluconeogenesis and decreasing insulin sensitivity.
3. A nurse is educating a client about taking levothyroxine. What should the
nurse include?
a) Take the medication with meals.
b) Take the medication at bedtime.
c) Take the medication on an empty stomach.
d) Take the medication with antacids.
Answer: c) Take the medication on an empty stomach.
Rationale: Levothyroxine absorption is optimal on an empty stomach, typically 30-
60 minutes before breakfast.
,4. Which laboratory value should be monitored in a client taking warfarin?
a) Hemoglobin
b) INR
c) Potassium
d) Creatinine
Answer: b) INR
Rationale: Warfarin effectiveness and safety are monitored using INR
(International Normalized Ratio) to assess clotting time.
5. A nurse is administering vancomycin IV. Which adverse effect should the nurse
be alert for?
a) Hepatotoxicity
b) Nephrotoxicity
c) Red man syndrome
d) Stevens-Johnson syndrome
Answer: c) Red man syndrome
Rationale: Rapid infusion of vancomycin can lead to flushing, hypotension, and
itching, collectively called red man syndrome.
6. A client is prescribed digoxin. Which finding indicates digoxin toxicity?
a) Tachycardia
b) Visual disturbances
c) Hypertension
d) Diarrhea
Answer: b) Visual disturbances
Rationale: Symptoms of digoxin toxicity include blurred or yellow-tinged vision,
fatigue, and gastrointestinal disturbances.
7. Which medication is used as the antidote for benzodiazepine overdose?
, a) Naloxone
b) Flumazenil
c) Protamine sulfate
d) Atropine
Answer: b) Flumazenil
Rationale: Flumazenil is a benzodiazepine antagonist that reverses sedation and
respiratory depression caused by benzodiazepines.
8. A client taking furosemide is at risk for which electrolyte imbalance?
a) Hyperkalemia
b) Hypokalemia
c) Hypernatremia
d) Hypercalcemia
Answer: b) Hypokalemia
Rationale: Furosemide is a loop diuretic that increases potassium excretion,
leading to hypokalemia.
9. A nurse is educating a client about nitroglycerin for chest pain. What should
the nurse include?
a) Take the medication only in the morning.
b) Store the medication in a warm, humid place.
c) Take up to three tablets, 5 minutes apart, for unrelieved chest pain.
d) Swallow the tablet with a full glass of water.
Answer: c) Take up to three tablets, 5 minutes apart, for unrelieved chest pain.
Rationale: Sublingual nitroglycerin should be taken as described for acute angina.
If pain persists, emergency care is needed.
10. What is a contraindication for administering metformin to a client?
a) History of liver failure
b) Current insulin therapy
