ASCP CG Certification Practice
QUESTIONS WITH VERIFIED
ANSWERS/////UPDATED VERSION 2025
"Starring-in" is a method of=====Immobilizing
the tissue in the culture vessel
24 hours after culture initiation, a single dish
from an amniotic fluid turns cloudy. Which
cultures should be disposed?=====The single
cloudy dish only
46,XY,der(9)(t(9;10)(q32;q12). What term best
describes this written
karyotype?=====Unbalanced
("der" means "a derivative chromosome"; "t"
translocation. This indi. has only one copy of
chromosome 9q from band 9q33 to 9qter),
therefore is unbalanced
,50% of cells from an amniotic flask have
92,XXYY and the other 50% have 46,XY. This
probably indicated:=====Pseudomosaicism
A blood sample can be used to study the
cytogenetics of a malignancy only
if:=====Dividing leukemic cells are present in
circulation
A bone marrow sample collected in transport
medium is leaking into the sealed plastic bag
in which it was transported. The technologist
should_______.=====Clean up the tube while
wearing gloves
A change of 1 pH unit in culture medium is
caused by a ________ change in CO2
concentration.=====10-fold
A Cri-du-chat patient has a chromosome
abnormality of:=====r(5)(p15.1q35)
,(this ring chromosome is missing the tip end of
5p and the tip end of 5q. Deletion of 5p15 is
cri-du-chat syndrome)
A fetus with an increased risk for trisomy 18
would have a serum analytes that is:=====low
AFP, low hCG, and low uE3
AFP = Alpha feto protein
hCG = human chorionic gonadotropin
uE3 = Unconjugated estriol
A laboratory' quality assurance program
includes _______________.=====Proficiency
testing
A MLL FISH gave the following signal pattern
1F 1R 1G. What is the ISCN of this
cell?=====nuc ish (MLLx2)(5?MLL sep
3?MLLx1)
A new hypotonic solution causes
overspreading of chromosomes. What
, technique can be used to prevent the
overspreading?=====Reduce the drying time
A regulatory inspecter requests a copy of a lab
patient's record for his inspection files, the
tech should:=====Deny the inspector a copy of
the record
See HIPAA compliance policy
A tech suspects an inversion of chrom 9 with
G-banding analysis. What banding technique
would confirm this?=====C-banding
A technologist wants to stain chromosomes
using a banding technique that manifests AT-
rich regions on chromosomes. What staining
procedure should he use?=====QFQ
According to CAP regulations, what is the
minimum band level for consitutional
specimens?=====400
QUESTIONS WITH VERIFIED
ANSWERS/////UPDATED VERSION 2025
"Starring-in" is a method of=====Immobilizing
the tissue in the culture vessel
24 hours after culture initiation, a single dish
from an amniotic fluid turns cloudy. Which
cultures should be disposed?=====The single
cloudy dish only
46,XY,der(9)(t(9;10)(q32;q12). What term best
describes this written
karyotype?=====Unbalanced
("der" means "a derivative chromosome"; "t"
translocation. This indi. has only one copy of
chromosome 9q from band 9q33 to 9qter),
therefore is unbalanced
,50% of cells from an amniotic flask have
92,XXYY and the other 50% have 46,XY. This
probably indicated:=====Pseudomosaicism
A blood sample can be used to study the
cytogenetics of a malignancy only
if:=====Dividing leukemic cells are present in
circulation
A bone marrow sample collected in transport
medium is leaking into the sealed plastic bag
in which it was transported. The technologist
should_______.=====Clean up the tube while
wearing gloves
A change of 1 pH unit in culture medium is
caused by a ________ change in CO2
concentration.=====10-fold
A Cri-du-chat patient has a chromosome
abnormality of:=====r(5)(p15.1q35)
,(this ring chromosome is missing the tip end of
5p and the tip end of 5q. Deletion of 5p15 is
cri-du-chat syndrome)
A fetus with an increased risk for trisomy 18
would have a serum analytes that is:=====low
AFP, low hCG, and low uE3
AFP = Alpha feto protein
hCG = human chorionic gonadotropin
uE3 = Unconjugated estriol
A laboratory' quality assurance program
includes _______________.=====Proficiency
testing
A MLL FISH gave the following signal pattern
1F 1R 1G. What is the ISCN of this
cell?=====nuc ish (MLLx2)(5?MLL sep
3?MLLx1)
A new hypotonic solution causes
overspreading of chromosomes. What
, technique can be used to prevent the
overspreading?=====Reduce the drying time
A regulatory inspecter requests a copy of a lab
patient's record for his inspection files, the
tech should:=====Deny the inspector a copy of
the record
See HIPAA compliance policy
A tech suspects an inversion of chrom 9 with
G-banding analysis. What banding technique
would confirm this?=====C-banding
A technologist wants to stain chromosomes
using a banding technique that manifests AT-
rich regions on chromosomes. What staining
procedure should he use?=====QFQ
According to CAP regulations, what is the
minimum band level for consitutional
specimens?=====400
