NURS6630 EXAM //NURS 6630
PSYCHOPHARMACOLOGY MIDTERM EXAM 2
VERSIONS ACTUAL MIDTERM EXAM SUMMER QRT|
NEWEST UPDATE WALDEN UNIVERSITY|| WELL
GRADED A+
In the synaptic cleft, Monoamine Oxidase A breaks down: - CORRECT ANSWERS-
Serotonin, Norepinephrine, and Dopamine
In the synaptic cleft, Monoamine Oxidase B breaks down: - CORRECT ANSWERS-
Dopamine
MAOIs are especially effective in: - CORRECT ANSWERS-Atypical depression (mood
responds to positive events and symptoms include increased appetite, weight gain,
sleepiness, and fatigue)
Non-selective MAOIs inhibit enzymes: - CORRECT ANSWERS-MAO-A and MAO-B
Selective MAOIs only inhibit the enzyme: - CORRECT ANSWERS-MAO-B
Three non-selective MAOIs: - CORRECT ANSWERS-dicarboxamide, phenelzine,
tranylcypromine
Non-selective MAOIs increase the levels of these neurotransmitters: - CORRECT
ANSWERS-Serotonin, Norepinephrine, Dopamine
These three non-selective MAOIs bind irreversibly to MAO enzymes to permanently
block their function: - CORRECT ANSWERS-dicarboxamide, phenelzine,
tranylcypromine
Two selective MAOIs: - CORRECT ANSWERS-selegeline, rasagiline
Selective MAOIs increase the level of this neurotransmitter: - CORRECT ANSWERS-
Dopamine
These selective MAOIs are more commonly prescribed to treat Parkinson's Disease (a
neurodegenerative disorder that effects the dopaminergic neurons in the substantia
nigra region of the brain): - CORRECT ANSWERS-selegeline, rasagiline
Adverse effects of MAOIs include: - CORRECT ANSWERS-Serotonin syndrome and
hypertensive crisis
, Before starting another antidepressant MAOIs should be stopped for at least: -
CORRECT ANSWERS-Two weeks (to allow for the body to replace MAO enzymes so
that serotonin syndrome does not occur)
Five main symptoms of hypertensive crisis: - CORRECT ANSWERS-hyperthermia,
hypertension, tachycardia, arrhythmias, agitation
Hypertensive crisis commonly occurs when people taking MAOIs consume foods or
drinks high in: - CORRECT ANSWERS-tyramine (cheese, wine, beer, cured/smoked
meats)
Foods and drinks rich in tyramine: - CORRECT ANSWERS-cheese, wine, beer,
cured/smoked meats
When uninhibited, these two enzymes are responsible for breaking down tyramine: -
CORRECT ANSWERS-MAO-A and MAO-B
When tyramine is not broken down, it increases the release of this neurotransmitter,
which causes hypertensive crisis: - CORRECT ANSWERS-Norepinephrine
Due to its action as an adrenergic antagonist this drug is the treatment of hypertensive
crisis: - CORRECT ANSWERS-Phentolamine
TCAs are subdivided into these two groups: - CORRECT ANSWERS-Tertiary TCAs and
Secondary TCAs
Three Tertiary TCAs: - CORRECT ANSWERS-amitriptyline, imipramine, clomipramine
Two Secondary TCAs: - CORRECT ANSWERS-desipramine, nortriptyline
Tertiary TCAs are non-selective and act on: - CORRECT ANSWERS-Serotonin and
Norephinephrine transporters (increase 5HT and NE)
Secondary TCAs are selective and act only on: - CORRECT ANSWERS-
Norepinephrine transporters (increase NE)
Therapeutic benefits from TCAs typically take approximately: - CORRECT ANSWERS-
2-4 weeks
In addition to treatment of depression, other indications for TCAs include: - CORRECT
ANSWERS-Phobic disorders, chronic neuropathic pain, migraine prophylaxis
Medication specific indication for clomipramine: - CORRECT ANSWERS-OCD
Medication specific indication for imipramine: - CORRECT ANSWERS-Nocturnal
enuresis
PSYCHOPHARMACOLOGY MIDTERM EXAM 2
VERSIONS ACTUAL MIDTERM EXAM SUMMER QRT|
NEWEST UPDATE WALDEN UNIVERSITY|| WELL
GRADED A+
In the synaptic cleft, Monoamine Oxidase A breaks down: - CORRECT ANSWERS-
Serotonin, Norepinephrine, and Dopamine
In the synaptic cleft, Monoamine Oxidase B breaks down: - CORRECT ANSWERS-
Dopamine
MAOIs are especially effective in: - CORRECT ANSWERS-Atypical depression (mood
responds to positive events and symptoms include increased appetite, weight gain,
sleepiness, and fatigue)
Non-selective MAOIs inhibit enzymes: - CORRECT ANSWERS-MAO-A and MAO-B
Selective MAOIs only inhibit the enzyme: - CORRECT ANSWERS-MAO-B
Three non-selective MAOIs: - CORRECT ANSWERS-dicarboxamide, phenelzine,
tranylcypromine
Non-selective MAOIs increase the levels of these neurotransmitters: - CORRECT
ANSWERS-Serotonin, Norepinephrine, Dopamine
These three non-selective MAOIs bind irreversibly to MAO enzymes to permanently
block their function: - CORRECT ANSWERS-dicarboxamide, phenelzine,
tranylcypromine
Two selective MAOIs: - CORRECT ANSWERS-selegeline, rasagiline
Selective MAOIs increase the level of this neurotransmitter: - CORRECT ANSWERS-
Dopamine
These selective MAOIs are more commonly prescribed to treat Parkinson's Disease (a
neurodegenerative disorder that effects the dopaminergic neurons in the substantia
nigra region of the brain): - CORRECT ANSWERS-selegeline, rasagiline
Adverse effects of MAOIs include: - CORRECT ANSWERS-Serotonin syndrome and
hypertensive crisis
, Before starting another antidepressant MAOIs should be stopped for at least: -
CORRECT ANSWERS-Two weeks (to allow for the body to replace MAO enzymes so
that serotonin syndrome does not occur)
Five main symptoms of hypertensive crisis: - CORRECT ANSWERS-hyperthermia,
hypertension, tachycardia, arrhythmias, agitation
Hypertensive crisis commonly occurs when people taking MAOIs consume foods or
drinks high in: - CORRECT ANSWERS-tyramine (cheese, wine, beer, cured/smoked
meats)
Foods and drinks rich in tyramine: - CORRECT ANSWERS-cheese, wine, beer,
cured/smoked meats
When uninhibited, these two enzymes are responsible for breaking down tyramine: -
CORRECT ANSWERS-MAO-A and MAO-B
When tyramine is not broken down, it increases the release of this neurotransmitter,
which causes hypertensive crisis: - CORRECT ANSWERS-Norepinephrine
Due to its action as an adrenergic antagonist this drug is the treatment of hypertensive
crisis: - CORRECT ANSWERS-Phentolamine
TCAs are subdivided into these two groups: - CORRECT ANSWERS-Tertiary TCAs and
Secondary TCAs
Three Tertiary TCAs: - CORRECT ANSWERS-amitriptyline, imipramine, clomipramine
Two Secondary TCAs: - CORRECT ANSWERS-desipramine, nortriptyline
Tertiary TCAs are non-selective and act on: - CORRECT ANSWERS-Serotonin and
Norephinephrine transporters (increase 5HT and NE)
Secondary TCAs are selective and act only on: - CORRECT ANSWERS-
Norepinephrine transporters (increase NE)
Therapeutic benefits from TCAs typically take approximately: - CORRECT ANSWERS-
2-4 weeks
In addition to treatment of depression, other indications for TCAs include: - CORRECT
ANSWERS-Phobic disorders, chronic neuropathic pain, migraine prophylaxis
Medication specific indication for clomipramine: - CORRECT ANSWERS-OCD
Medication specific indication for imipramine: - CORRECT ANSWERS-Nocturnal
enuresis
