VTNE prep: Pharmacology Exam
Questions and Answers 100% Pass
Neonatal animals are less tolerant of certain drugs than older animals, because in neonates drugs are: -
✔✔(biotransformed)/Metabolised more slowly by the liver.
*At aprox. 1 month of age-the liver better equipped to metabolize drugs.
The majority of biotransformation (metabolization) of drugs occurs in the - ✔✔Liver
For this reason-patients in liver failure should avoid most drugs.
The generic name for the drug is also called the: - ✔✔Nonproprietary
You are asked to administer a drug that is supplied as an enteric-coated tablet at 100 mg, 50 mg, and 25
mg; you require 25 mg but have available 50-mg tablets only. You should - ✔✔Order 25mg tablets.
You should never divide enteric coated tablets.
10ml of a 2.5% solution of thiopental contains how many mg? - ✔✔250.
in this solution-there are 25mg/ml (2.5 x 10 = 25)
Since there are 10 ml, we multiply 25 by 10, which gives us 250.
Tadah!
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Bioavailibility refers to - ✔✔In pharmacology- this means what percentage of the drug administered is
actually going to the bloodstream
Cholinergic agents - ✔✔Slow the heart rate
Increase blood blow to the intestinal tract
Cause vessels to decrease in diameter
Acetaminophen is toxic to ___ - ✔✔cats
Aminoglycosides tend to be ________toxic and _____toxic. - ✔✔Nephro
Oto
Which statement is true regarding tetracycline? - ✔✔Currently many bacteria are resistant to them
Tetracyclines work by - ✔✔-They are bactericidal (kills them)
-They alter the permeability of the cell wall and cause lysis -but they are unable to penetrate the cell wall
of the bacterium.
Cephalosporin is closely related to which drug class? - ✔✔penicillin
They are both beta-lactam type drugs
Because of the manner they are excreted: Sulfonamides are often used to treat: - ✔✔UTI's
Fluroquinalones: such as enrofloxacin has been known to cause blindness in_________. - ✔✔Cats
Chloramphenicol should be avoided in ____________ due to the chance of causing aplastic anemia in
humans. - ✔✔Food producing animals.
Penicillins are mostly excreted by the - ✔✔Kidneys
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This drug, a benzodiazepine; has a tendency to react with plastic, and thus should NOT be drawn up
ahead of time. - ✔✔Diazepam
Griseofulvin acts on - ✔✔Dermatophytes
Side effects of solfonamides include - ✔✔Dry eye
skin erruptions
renal failure
Fluroquinalones, (floxin's) tend to have adverse effects in puppies and horses, why is this? - ✔✔Affects
cartilage growth.
Potentiated penicillin drugs work against - ✔✔b-lactamase producing bacteria
idophor - ✔✔such as betadine (see pictured)
these have a longer action that iodine alone.
Avermectins - ✔✔Ivermectin
Moxidectin
Salamectin
A risk to technicians that administer prostaglandins is: - ✔✔An asthma attack
Long term use of loop diuretics: such as furosemide can lead to side effects such as: - ✔✔Hypokalemia
IF given as a BOLUS- lidocaine can cause - ✔✔bradyarrythmia
What is the ratio between the toxic dose and therapeutic dose of a drug used as a measure of the relative
safety of the drug for a particular treatment? - ✔✔Therapeutic index
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