Membranes
Compiled By Simon Mwangi
Edition: 2024/25
, Science | Biochemistry I of X pages
1. 4 kinds of membrane proteins?
ReceptorsIon channels Adhesion molecules Transporters
2. What do ion channels do?
Mediate electrical signalling between cells
3. 4 types of receptors
Ligand-gated ion channels G-protein-coupled receptorsKinase-linked receptors Nuclear receptors
4. What kind of receptor does glucagon activate?
G-protein coupled receptors
5. What kind of receptor does insulin activate?
Receptor tyrosine kinases
6. Example of intracellular receptor
Nuclear receptor
7. What receptors do many drugs utilise?
G-protein coupled receptors
8. What does the alpha subunit stimulate when the G-protein coupled receptor is stimulated?
AC- adenelaine cyclase
9. What secondary messenger does AC produce?
Cyclic AMP
10. Example of what activates G-protein coupled receptors?
GlucagonAdrenalin
11. Example of what activates steroid hormone receptors
Sex hormones Cortisol
12. Are the responses to steroid hormone receptors faster or slower than G-protein coupled receptors?
Slower, because they are activating gene expression which can take days G-protein receptors act immediately,
13. What has a role in metastasis of cancer?
Integrins
14. Some common functions of membranes (6)
Define boundaries of cell Allow import and exportRetain metabolites and ions within the cellSense external
15. What is the main structure formed of?
Lipid bilayer
16. What stabilises membranes?
Noncovalent forces, especially hydrophobic effect and van der waals
Biochemistry 2024/25 Edition