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Pharmaceutical Toxicology Exam Questions
and Answers
Toxicology - Answers✓✓Branch of pharmacology that deals with the undesirable effects of chemicals on
living systems, from individual cells to human to complex systems.
Science of Poisons - Answers✓✓Branch of science that deals with poisons, their adverse effects and
treatment of disorder they produce.
Paracelsus - Answers✓✓The father of toxicology, founder of modern technology, who stated that 'All
things are poison and nothing is without poison; only the dose makes a thing not a poison.'
The dose makes the poison - Answers✓✓Interpretation by Paracelsus that all substances known to man
are poisons and only the dose determines the effect.
Toxicity - Answers✓✓The toxicity of a specific substance depends on a variety of factors, including how
much of the substance a person is exposed to, how they are exposed, and for how long.
Pedanius Dioscorides - Answers✓✓Greek physician in the court of the Roman emperor Nero who made
the first attempt to classify plants according to their toxic and therapeutic effect.
Classification of poisons - Answers✓✓Dioscorides categorized poisons into 3 groups—animal, vegetable,
and mineral.
Mechanisms of action - Answers✓✓Toxicologists are concerned with mechanisms of action and
exposure to chemicals as a cause of acute and chronic illness.
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Occupational exposure - Answers✓✓Toxicologists are involved in the recognition, identification, and
quantification of hazards resulting from occupational exposure to chemicals.
Public health aspects - Answers✓✓Toxicologists contribute to the public health aspects of chemicals in
air, water, other parts of the environment, food, and drugs.
Drug development - Answers✓✓Traditionally, toxicologists have been intimately involved in the
discovery and development of new drugs, food additives, and pesticides.
Standards and regulations - Answers✓✓Toxicologists participate in the development of standards and
regulations designed to protect human health and the environment from the adverse effects of
chemicals.
Adverse effects - Answers✓✓Toxicology studies the adverse effects of xenobiotics.
Xenobiotics - Answers✓✓Substances that are foreign to the biological system, which toxicology studies
for their adverse effects.
Acute illness - Answers✓✓Toxicologists study chemicals as a cause of acute illness.
Chronic illness - Answers✓✓Toxicologists study chemicals as a cause of chronic illness.
Utilization of data - Answers✓✓The art of toxicology consists of utilization of data to predict outcomes
of exposure in human and animal populations.
Observational phase - Answers✓✓The science of toxicology is defined as the observational and data-
gathering phase.
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Pharmacology - Answers✓✓Toxicologists contribute to physiology and pharmacology by using toxic
chemicals to understand physiological phenomena.
Toxicants - Answers✓✓Substances studied in toxicology that can cause adverse effects.
Environmental chemicals - Answers✓✓Toxicologists study the effects of chemicals present in the
environment, including air and water.
Food additives - Answers✓✓Toxicologists are involved in the discovery and development of food
additives.
Pesticides - Answers✓✓Toxicologists are involved in the discovery and development of pesticides.
IBN WAHSHIYYA - Answers✓✓Iraqi alchemist, agriculturalist, farm toxicologist.
MATHIEU JOSEPH BONAVENTURE ORFILA - Answers✓✓Spanish physician who founded the science of
toxicology.
JEAN STAS - Answers✓✓First person to successfully isolate plant poisons from human tissue.
Poison - Answers✓✓Any agent which may cause a serious body injury, disease or death when applied,
introduced into, or developed within the body.
Intoxication - Answers✓✓Toxicity associated with any substance.
Hazard - Answers✓✓Likelihood that an injury may occur in given situation or setting.
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Risk - Answers✓✓Expected frequency of the occurrence of an undesirable effect arising from exposure
to a chemical substance or physical agent.
Overdose - Answers✓✓Intentional exposure to toxic agent with the intent of causing self-injury or
death; exposure to excessive amount of substance.
Poisoning - Answers✓✓Accidental exposure to toxic agent; a clinical toxicity secondary to accidental
exposure then development of harmful effects following exposure to chemicals.
Toxicokinetics - Answers✓✓The study of the time dependence of physiological processes on a toxicant,
and ultimately its response or effect.
Toxicodynamics - Answers✓✓Refer to the quantitative description of the effects of a toxicant on a
biological system.
Clinical Toxicology - Answers✓✓The analysis and assessment of overdose and poisoning effects to the
patient.
Environmental Toxicology - Answers✓✓The study of the impact of pollutants to human health.
Experimental Toxicology - Answers✓✓Investigation of the toxic effects of chemicals in the biological
species.
Descriptive Toxicology - Answers✓✓Conduct toxicity testing of the poison to identify in order to gather
product information on product acceptance, safety requirements and regulatory standards.
Regulatory Toxicology - Answers✓✓Whether the drug dose is safe or not.