NUR 641E final Exam Questions And
Answers 100% Pass
Pharmacokinetics involves - - -
correct answer ✅absorption, distribution, metabolism and
elimination).
Absorption: - - -
correct answer ✅absorption from the administration site either
directly or indirectly into the blood/plasma.
Distribution: - - -
correct answer ✅reversibly or irreversibly move from the
bloodstream into the interstitial and intracellular
Metabolism: - - -
correct answer ✅biotransformed via hepatic metabolism or by
other tissues.
Elimination: - - -
correct answer ✅tissues. lastly, the drug and its metabolites are
eliminated from the body.
route of administration with the highest bioavailability - - -
correct answer ✅intravenous; putting entire dose into a patient's
vein and bypassing absorption.
,NUR 641E final Exam Questions And
Answers 100% Pass
avoids first-pass metabolism - - -
correct answer ✅Intravenous route
administration has variable and erratic absorption. n - - -
correct answer ✅Rectal administration
4. Steady state (SS) - - -
correct answer ✅absorption. n is usually reached within 4-5 half-
lives of drug.
Half-life of a drug is - - -
correct answer ✅how long it takes for half the drug to be excreted
from the body. Determines how frequently the drug must be
administered. Predicts how long toxic effects can last.is constant
with first-order pharmacokinetics of a drug.
Zero-order (nonlinear) pharmacokinetics - - -
correct answer ✅means a drug is metabolized at a constant rate
per unit time.
,NUR 641E final Exam Questions And
Answers 100% Pass
CYP3A4 substrate drugs - - -
correct answer ✅may have enhanced activity if any CYP3A4
inducer drugs are used along with it.
Drug development process involves these steps according to the
FDA: - - -
correct answer ✅Discovery: laboratory research to develop the
new drug. Preclinical research with animal testing for safety (Phase
I). Clinical research on human subjects for medication safety (Phase
II). Clinical research in humans comparing the new drug to accepted
medications placebo depending on the study (Phase III). FDA review
of the results to determine approval. Post marketing study to
identify adverse effects not found in earlier clinical studies (Phase
IV)
2. Medication safety organizations - - -
correct answer ✅The Institute for Safe Medication Practices
(ISMP) The Institute of Medicine (IOM) The Joint Commission The
National Coordinating Council for Medication Error Reporting and
Prevention (NCC MERP) Food and Drug Administration (FDA) Safe
Use Initiative
Two basic type of ADRS: - - -
correct answer ✅pharmacological and idiosyncratic.
, NUR 641E final Exam Questions And
Answers 100% Pass
85% to 90% of ADRS - - -
correct answer ✅are pharmacological.
Adverse drug reactions are usually preventable, - - -
correct answer ✅frequently occur in a hospital or nursing home
setting, and include medication errors, adverse drug effects, and
allergic idiosyncratic type reactions.
ADRS are not commonly reported; - - -
correct answer ✅the FDA does not mandate that ADRS be
reported.
Polypharmacy - - -
correct answer ✅involves using multiple health care providers for
care, using multiple medications, and using several pharmacies
prescription filling.
Angiotensin converting enzyme inhibitors (ACEIS): - - -
correct answer ✅lisinopril, captopril, enalapril, ramipril,
benazepril, fosinopril.
Answers 100% Pass
Pharmacokinetics involves - - -
correct answer ✅absorption, distribution, metabolism and
elimination).
Absorption: - - -
correct answer ✅absorption from the administration site either
directly or indirectly into the blood/plasma.
Distribution: - - -
correct answer ✅reversibly or irreversibly move from the
bloodstream into the interstitial and intracellular
Metabolism: - - -
correct answer ✅biotransformed via hepatic metabolism or by
other tissues.
Elimination: - - -
correct answer ✅tissues. lastly, the drug and its metabolites are
eliminated from the body.
route of administration with the highest bioavailability - - -
correct answer ✅intravenous; putting entire dose into a patient's
vein and bypassing absorption.
,NUR 641E final Exam Questions And
Answers 100% Pass
avoids first-pass metabolism - - -
correct answer ✅Intravenous route
administration has variable and erratic absorption. n - - -
correct answer ✅Rectal administration
4. Steady state (SS) - - -
correct answer ✅absorption. n is usually reached within 4-5 half-
lives of drug.
Half-life of a drug is - - -
correct answer ✅how long it takes for half the drug to be excreted
from the body. Determines how frequently the drug must be
administered. Predicts how long toxic effects can last.is constant
with first-order pharmacokinetics of a drug.
Zero-order (nonlinear) pharmacokinetics - - -
correct answer ✅means a drug is metabolized at a constant rate
per unit time.
,NUR 641E final Exam Questions And
Answers 100% Pass
CYP3A4 substrate drugs - - -
correct answer ✅may have enhanced activity if any CYP3A4
inducer drugs are used along with it.
Drug development process involves these steps according to the
FDA: - - -
correct answer ✅Discovery: laboratory research to develop the
new drug. Preclinical research with animal testing for safety (Phase
I). Clinical research on human subjects for medication safety (Phase
II). Clinical research in humans comparing the new drug to accepted
medications placebo depending on the study (Phase III). FDA review
of the results to determine approval. Post marketing study to
identify adverse effects not found in earlier clinical studies (Phase
IV)
2. Medication safety organizations - - -
correct answer ✅The Institute for Safe Medication Practices
(ISMP) The Institute of Medicine (IOM) The Joint Commission The
National Coordinating Council for Medication Error Reporting and
Prevention (NCC MERP) Food and Drug Administration (FDA) Safe
Use Initiative
Two basic type of ADRS: - - -
correct answer ✅pharmacological and idiosyncratic.
, NUR 641E final Exam Questions And
Answers 100% Pass
85% to 90% of ADRS - - -
correct answer ✅are pharmacological.
Adverse drug reactions are usually preventable, - - -
correct answer ✅frequently occur in a hospital or nursing home
setting, and include medication errors, adverse drug effects, and
allergic idiosyncratic type reactions.
ADRS are not commonly reported; - - -
correct answer ✅the FDA does not mandate that ADRS be
reported.
Polypharmacy - - -
correct answer ✅involves using multiple health care providers for
care, using multiple medications, and using several pharmacies
prescription filling.
Angiotensin converting enzyme inhibitors (ACEIS): - - -
correct answer ✅lisinopril, captopril, enalapril, ramipril,
benazepril, fosinopril.
