EXAM BANK FOR MICB 212- QUESTIONS WITH VERIFIED SOLUTIONS LATEST UPDATE (2024-2025)
Innate Immune System - Answers Quick & Non-specific
Adaptive Immune System - Answers slower response; more specific immune response
PAMP (pathogen associated molecular patterns) - Answers molecules present on pathogens and not self
Toll-like receptors (TLRs) - Answers on host cells attach to pathogen-associated molecular patterns
(PAMPs)
C3a and C5a - Answers Bind to mast cells and cause them to release histamine and other chemicals that
increase blood vessel permeability during inflammation. C5a also functions as powerful chemotactic
factor that attracts phagocytes to site of infection.
C3b - Answers opsonin- an antibody or other substance which binds to foreign microorganisms or cells
making them more susceptible to phagocytosis.
C35 - Answers Recruits proteins to form MAC (membrane attack complex), Lyses cells
membrane attack complex (MAC) - Answers complement system components assembled to form pores
in membranes of invading cells
inflammatory response - Answers nonspecific defense against infection, characterized by redness, heat,
swelling, and pain
MHC I - Answers molecules found on every body cell that presents antigen; signals cytotoxic T to
destroy, CD8
MHC II - Answers molecules found on macrophages, B cells, and activated T cells; signal helper T cells,
CD4
T cell - Answers a lymphocyte that identifies pathogens and distinguishes one pathogen from another
TCR - Answers The T cell receptor on the majority of T cells - it recognizes antigen-MHC complexes
CD3 - Answers Expressed on all T cells and is needed as a signal transducer for the T cell receptor
CD4 - Answers Interacts with MHC class II molecules, Helper T Cell
CD8 - Answers A surface protein, present on most cytotoxic T cells, that binds to class I MHC molecules,
enhancing the interaction between the T cell and a target cell.
activate T cells - Answers 1. TCR binds with MHC, CD3 and Coreceptor CD4 or CD8 Bind, CD3 signals
nucleus
Innate Immune System - Answers Quick & Non-specific
Adaptive Immune System - Answers slower response; more specific immune response
PAMP (pathogen associated molecular patterns) - Answers molecules present on pathogens and not self
Toll-like receptors (TLRs) - Answers on host cells attach to pathogen-associated molecular patterns
(PAMPs)
C3a and C5a - Answers Bind to mast cells and cause them to release histamine and other chemicals that
increase blood vessel permeability during inflammation. C5a also functions as powerful chemotactic
factor that attracts phagocytes to site of infection.
C3b - Answers opsonin- an antibody or other substance which binds to foreign microorganisms or cells
making them more susceptible to phagocytosis.
C35 - Answers Recruits proteins to form MAC (membrane attack complex), Lyses cells
membrane attack complex (MAC) - Answers complement system components assembled to form pores
in membranes of invading cells
inflammatory response - Answers nonspecific defense against infection, characterized by redness, heat,
swelling, and pain
MHC I - Answers molecules found on every body cell that presents antigen; signals cytotoxic T to
destroy, CD8
MHC II - Answers molecules found on macrophages, B cells, and activated T cells; signal helper T cells,
CD4
T cell - Answers a lymphocyte that identifies pathogens and distinguishes one pathogen from another
TCR - Answers The T cell receptor on the majority of T cells - it recognizes antigen-MHC complexes
CD3 - Answers Expressed on all T cells and is needed as a signal transducer for the T cell receptor
CD4 - Answers Interacts with MHC class II molecules, Helper T Cell
CD8 - Answers A surface protein, present on most cytotoxic T cells, that binds to class I MHC molecules,
enhancing the interaction between the T cell and a target cell.
activate T cells - Answers 1. TCR binds with MHC, CD3 and Coreceptor CD4 or CD8 Bind, CD3 signals
nucleus
