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Chapter 1 The Foundations of Biochemistry
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Multiple Choice Questions
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1. Cellularkfoundations
Pages:k3-4kk Difficulty:k1 Ans:kC
Inkakbacterialkcell,kthekDNAkiskinkthe:

A) cellkenvelope.
B) cellk membrane.
C) nucleoid.
D) nucleus.
E) ribosomes.

2. Cellularkfoundations
Page:k4 Difficulty:k1 Ans:kE
Akmajorkchangekoccurringkinkthek evolutionkofkeukaryoteskfromkprokaryoteskwaskthekdevelo

A) DNA.
B) kphotosynthetick capability.


C) kplasmak membranes.


D) ribosomes.
E) theknucleus.

3. Cellularkfoundations
Page:k4 Difficulty:k1 Ans:kB
Inkeukaryotes,ktheknucleuskiskenclosedkbykak doublekmembranekcalledkthe:

A) cellk membrane.
B) nuclearkenvelope. @thebo
C) nucleolus.
D) nucleoplasm.
E) nucleosome.

4. Cellularkfoundations
Page:k4 Difficulty:k1 Ans:kC
Thekdimensionskofklivingkcellskareklimited,konktheklowerkendkbykthekminimumknumberkofkbio
rykforkfunction,kandkonkthekupperkendkbykthekratek ofkdiffusionkofksolutesksuchkaskoxygen.
Exceptkforkhighlykelongatedkcells,ktheykusuallykhaveklengthskandkdiameterskinkthek rangekof:

A) 0.1kµmktok10k µm.
B) 0.3kµmktok30k µm.
C) 0.3kµmktok100k µm.
D) 1kµmktok100k µm.
E) 1kµmktok300k µm.

,2 Chapterk1kk ThekFoundationskofkB



5. Cellularkfoundations
Page:kk5 Difficulty:kk2 Ans:kkB
ThekbacteriumkE.k colikrequiresksimplekorganickmoleculeskforkgrowthkandk energy—itkiskther

A) chemoautotroph.
B) chemoheterotroph.
C) lithotroph.
D) kphotoautotroph.


E) kphotoheterotroph.




6. Cellularkfoundations
Page:kk10 Difficulty:kk2 Ans:kkB
Whichkonekofkthekfollowingkhaskthek cellularkcomponentskarrangedkinkorderkofk increasingks

A) Aminokacidk<kproteink<k mitochondrionk<kribosome
B) Aminokacidk<k proteink<k ribosomek<k mitochondrion
C) Aminokacidk<kribosomek<k proteink<kmitochondrion
D) Proteink<kaminokacidk<k mitochondrionk<kribosome
E) Proteink<kribosomek<k mitochondrionk<kaminokacid

7. Cellularkfoundations
Page:kk11 Difficulty:kk2 Ans:kkA
Thekthree-
dimensionalkstructurekofkmacromoleculeskiskformedkandkmaintainedkprimarilykthroughknon
ns.k Whichkonekofkthekfollowingkisk notkconsideredkak noncovalentkinteraction?

A) carbon-carbonkbonds
B) hydrogenkbonds
C) hydrophobickinteractions
D) ionickinteractions
E) vankderkWaalskinteractions

8. Chemicalkfoundations
Page:kk12 Difficulty:kk2 Ans:kkE
Whichkonekofkthekfollowingkisk notkamongkthekfourk mostkabundantkelementskinklivingkorgan

A) Carbon
B) Hydrogen
C) kNitrogen


D) Oxygen
E) Phosphorus

9. Chemicalkfoundations
Page:kk13 Difficulty:kk1 Ans:kkB
Thekfourkcovalentkbondskinkmethanek(CHk4)karekarrangedkaroundkcarbonktokgivek whichkoneko
gkgeometries?

, Chapterk1k ThekFkoundationskofkk Bkiochemistry



10. Chemicalkfoundations
Page:k14 Difficulty:k1 Ans:kB
Whatkfunctionalkgroupskarekpresentkonkthiskmolecule?




A) etherkandkaldehyde
B) hydroxylkandkaldehyde
C) hydroxylkandkcarboxylickacid
D) hydroxylkandkester
E) hydroxylkandkketone

11. Chemicalkfoundations
Page:k16 Difficulty:k1 Ans:kD
Thekmacromoleculeskthatkservekinkthekstoragek andktransmissionkofkgenetickinformationkare:

A) carbohydrates.
B) lipids.
C) membranes.
D) nucleickacids.
E) kproteins.




12. Chemicalkfoundations
Page:k17 Difficulty:k1 Ans:kD
Stereoisomerskthatkareknonsuperimposablekmirrorkimageskofkeachkotherk arekknownkas:

A) anomers.
B) cis-transk isomers.
C) diastereoisomers.
D) enantiomers.
E) geometrickisomers.

13. Chemicalkfoundations
Page:k20 Difficulty:k3 Ans:kE
Thekenzymekfumarasekcatalyzeskthekreversiblekhydrationkofkfumarickacidktokl-
malate,kbutkitkwillknotkcatalyzekthekhydrationkofkmaleickacid,kthekciskisomerkofkfumarickacid
amplekof:

A) kbiologicalkactivity.
B) chiralkactivity.
C) racemization.
D) stereoisomerization.
E) stereospecificity.