BIO 351 MODULE 1 EXAM QUESTIONS AND
ANSWERS
which of the following statements is false?
differentiation is the only reversible step
cell fates are reversible after specification
differentiation involves changes in gene expression, morphology, and function
cell fates are irreversible after determination - ANSWER differentiation is the
only reversible step
which of the following is the correct order of developmental steps that create a
specialized cell type?
(differentiation, specification, determination) - ANSWER specification,
determination, differentiation
as cells move along the continuum from stem cell to differentiated cell which of
the following correctly identifies the properties of a determined cell?
differentiates in a non-neutral environment, but fate is irreversible
can differentiate in a non-neutral environment and its fate is irreversible
can differentiate in a neutral environment and its fate is reversible
it cannot differentiate. - ANSWER can differentiate in a non-neutral
environment and its fate is irreversible
killing P2 cells disrupts EMS cell differentiation which of the following
describes what happens?
conditional specification of the P2 cell
autonomous specification of the EMS cell
autonomous specification of the P2 cell
, conditional specification of the EMS cell - ANSWER conditional specification
of the EMS cell
which of the following are TRUE properties of embryonic stem cells?
they are pluripotent and will self-renew indefnitely when cultured in vitro
they can only become cells of the germline
they are multipoint but can only become the extra embryonic structures in vivo-
ANSWER they are pluripotent, and will self-renew indefnitely when cultured
in vitro
which of the following best describes asymmetric cell division?
meiosis
mitosis producing unequal daughter cells that ensures stem cell self-renewal
a property full of differentiation cells only
normal mitotic cell division - ANSWER mitosis producing unequal daughter
cells that ensures stem cell self-renewal
which of the following is a distinguishing feature of ES cells?
only embryonic stem cells are derived from the primitive endoderm
ES cells are pluripotent and give rise to the epiblast
tissue specific stem cells can be isolated from the inner cel mass of the
blastocyst, but embryonic stem cells cannot
embryonic stem cells persist into adulthood and can become any cell type -
ANSWER ES cells are pluripotent and give rise to the epiblast
ANSWERS
which of the following statements is false?
differentiation is the only reversible step
cell fates are reversible after specification
differentiation involves changes in gene expression, morphology, and function
cell fates are irreversible after determination - ANSWER differentiation is the
only reversible step
which of the following is the correct order of developmental steps that create a
specialized cell type?
(differentiation, specification, determination) - ANSWER specification,
determination, differentiation
as cells move along the continuum from stem cell to differentiated cell which of
the following correctly identifies the properties of a determined cell?
differentiates in a non-neutral environment, but fate is irreversible
can differentiate in a non-neutral environment and its fate is irreversible
can differentiate in a neutral environment and its fate is reversible
it cannot differentiate. - ANSWER can differentiate in a non-neutral
environment and its fate is irreversible
killing P2 cells disrupts EMS cell differentiation which of the following
describes what happens?
conditional specification of the P2 cell
autonomous specification of the EMS cell
autonomous specification of the P2 cell
, conditional specification of the EMS cell - ANSWER conditional specification
of the EMS cell
which of the following are TRUE properties of embryonic stem cells?
they are pluripotent and will self-renew indefnitely when cultured in vitro
they can only become cells of the germline
they are multipoint but can only become the extra embryonic structures in vivo-
ANSWER they are pluripotent, and will self-renew indefnitely when cultured
in vitro
which of the following best describes asymmetric cell division?
meiosis
mitosis producing unequal daughter cells that ensures stem cell self-renewal
a property full of differentiation cells only
normal mitotic cell division - ANSWER mitosis producing unequal daughter
cells that ensures stem cell self-renewal
which of the following is a distinguishing feature of ES cells?
only embryonic stem cells are derived from the primitive endoderm
ES cells are pluripotent and give rise to the epiblast
tissue specific stem cells can be isolated from the inner cel mass of the
blastocyst, but embryonic stem cells cannot
embryonic stem cells persist into adulthood and can become any cell type -
ANSWER ES cells are pluripotent and give rise to the epiblast
