Ch. 14 Lehninger biochem test bank
h h h h h
Glycolysishishthehnamehgivenhtohahmetabolichpathwayhoccurringhinhmanyhdifferenthcellhtypes.hIthconsistshofh
11henzyma chstepshthathconverthglucosehtohlac chacid.hGlycolysishishanhexamplehof:h
A)haerobichmetabolism.
B)hanabolichmetabolism.
C)hahnethreduc vehprocess.
D)hfermenta on.
E)hoxida vehphosphoryla on.h-hD
Thehconversionhofh1hmolhofhfructoseh1,6-
bisphosphatehtoh2hmolhofhpyruvatehbyhthehglycoly chpathwayhresultshinhahnethforma onhof:h
A)h1hmolhofhNAD+handh2hmolhofhATP.h
B)h1hmolhofhNADHhandh1hmolhofhATP.h
C)h2hmolhofhNAD+handh4hmolhofhATP.h
D)h2hmolhofhNADHhandh2hmolhofhATP.h
E)h2hmolhofhNADHhandh4hmolhofhATP.h-hE
Whenhahmixturehofhglucoseh6-phosphatehandhfructoseh6-
phosphatehishincubatedhwithhthehenzymehphosphohexosehisomerase,hthehfinalhmixturehcontainshtwicehash
muchhglucoseh6-phosphatehashfructoseh6-
phosphate.hWhichhonehofhthehfollowinghstatementshishmosthnearlyhcorrect,hwhenhappliedhtohthehreac onh
belowh(Rh=h8.315hJ/mol·KhandhTh=h298hK)?
Glucoseh6-phosphateh↔hfructoseh6-phosphateh
A)hG'°hish+1.7hkJ/mol.h
B)hG'°hish-1.7hkJ/mol.h
, C)hG'°hishincalculablyhlargehandhnega ve.h
D)hG'°hishincalculablyhlargehandhposi ve.h
E)hG'°hishzero.h-hA
Inhglycolysis,hfructoseh1,6-bisphosphatehishconvertedhtohtwohproductshwithhahstandardhfree-
energyhchangeh(G'°)hofh23.8hkJ/mol.hUnderhwhathcondi onsh(encounteredhinhahnormalhcell)hwillhthehfree-
energyhchangeh(G)hbehnega ve,henablinghthehreac onhtohproceedhtohthehright?h
A)hIfhthehconcentra onshofhthehtwohproductsharehhighhrela vehtohthathofhfructoseh1,6-bisphosphate.
B)hThehreac onhwillhnothgohtohthehrighthspontaneouslyhunderhanyhcondi onshbecausehthehG'°hishposi ve.h
C)hUnderhstandardhcondi ons,henoughhenergyhishreleasedhtohdrivehthehreac onhtohthehright.h
D)hWhenhtherehishahhighhconcentra onhofhfructoseh1,6-
bisphosphatehrela vehtohthehconcentra onhofhproducts.h
E)hWhenhtherehishahhighhconcentra onhofhproductshrela vehtohthehconcentra onhofhfructoseh1,6-
bisphosphate.h-hD
Glucosehlabeledhwithh14ChinhC-1handhC-6hgiveshrisehinhglycolysishtohpyruvatehlabeledhin:h
A)hAhandhC.h
B)hallhthreehcarbons.h
C)hitshcarbonylhcarbon.h
D)hitshcarboxylhcarbon.h
E)hitshmethylhcarbon.h-hE
Ifhglucosehlabeledhwithh14ChathC-
2hwerehmetabolizedhinhthehliver,hthehfirsthradioac vehpyruvatehformedhwouldhbehlabeledhin:h
A)hallhthreehcarbons.h
B)hbothhAhandhC.h
C)hitshcarbonylhcarbon.h
h h h h h
Glycolysishishthehnamehgivenhtohahmetabolichpathwayhoccurringhinhmanyhdifferenthcellhtypes.hIthconsistshofh
11henzyma chstepshthathconverthglucosehtohlac chacid.hGlycolysishishanhexamplehof:h
A)haerobichmetabolism.
B)hanabolichmetabolism.
C)hahnethreduc vehprocess.
D)hfermenta on.
E)hoxida vehphosphoryla on.h-hD
Thehconversionhofh1hmolhofhfructoseh1,6-
bisphosphatehtoh2hmolhofhpyruvatehbyhthehglycoly chpathwayhresultshinhahnethforma onhof:h
A)h1hmolhofhNAD+handh2hmolhofhATP.h
B)h1hmolhofhNADHhandh1hmolhofhATP.h
C)h2hmolhofhNAD+handh4hmolhofhATP.h
D)h2hmolhofhNADHhandh2hmolhofhATP.h
E)h2hmolhofhNADHhandh4hmolhofhATP.h-hE
Whenhahmixturehofhglucoseh6-phosphatehandhfructoseh6-
phosphatehishincubatedhwithhthehenzymehphosphohexosehisomerase,hthehfinalhmixturehcontainshtwicehash
muchhglucoseh6-phosphatehashfructoseh6-
phosphate.hWhichhonehofhthehfollowinghstatementshishmosthnearlyhcorrect,hwhenhappliedhtohthehreac onh
belowh(Rh=h8.315hJ/mol·KhandhTh=h298hK)?
Glucoseh6-phosphateh↔hfructoseh6-phosphateh
A)hG'°hish+1.7hkJ/mol.h
B)hG'°hish-1.7hkJ/mol.h
, C)hG'°hishincalculablyhlargehandhnega ve.h
D)hG'°hishincalculablyhlargehandhposi ve.h
E)hG'°hishzero.h-hA
Inhglycolysis,hfructoseh1,6-bisphosphatehishconvertedhtohtwohproductshwithhahstandardhfree-
energyhchangeh(G'°)hofh23.8hkJ/mol.hUnderhwhathcondi onsh(encounteredhinhahnormalhcell)hwillhthehfree-
energyhchangeh(G)hbehnega ve,henablinghthehreac onhtohproceedhtohthehright?h
A)hIfhthehconcentra onshofhthehtwohproductsharehhighhrela vehtohthathofhfructoseh1,6-bisphosphate.
B)hThehreac onhwillhnothgohtohthehrighthspontaneouslyhunderhanyhcondi onshbecausehthehG'°hishposi ve.h
C)hUnderhstandardhcondi ons,henoughhenergyhishreleasedhtohdrivehthehreac onhtohthehright.h
D)hWhenhtherehishahhighhconcentra onhofhfructoseh1,6-
bisphosphatehrela vehtohthehconcentra onhofhproducts.h
E)hWhenhtherehishahhighhconcentra onhofhproductshrela vehtohthehconcentra onhofhfructoseh1,6-
bisphosphate.h-hD
Glucosehlabeledhwithh14ChinhC-1handhC-6hgiveshrisehinhglycolysishtohpyruvatehlabeledhin:h
A)hAhandhC.h
B)hallhthreehcarbons.h
C)hitshcarbonylhcarbon.h
D)hitshcarboxylhcarbon.h
E)hitshmethylhcarbon.h-hE
Ifhglucosehlabeledhwithh14ChathC-
2hwerehmetabolizedhinhthehliver,hthehfirsthradioac vehpyruvatehformedhwouldhbehlabeledhin:h
A)hallhthreehcarbons.h
B)hbothhAhandhC.h
C)hitshcarbonylhcarbon.h
