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WCU Patho Week 7 - Ch. 36, 37, 38, 41 Exam
Questions And Answers
Gastroesophageal Reflux Disease (GERD) Description - Answers✔Backflow of gastric contents
into esophagus through lower esophageal sphincter (LES)
Inflammation caused by reflux of highly acidic material (esophagitis)
GERD Comfort Treatment - Answers✔Over-the-counter antacids and histamine-blocking
medications
GERD Hospital Treatment - Answers✔Proton pump inhibitors (PPI) halts and reverses changes
of chronic GERD
Reflux Esophagitis Description - Answers✔Esophageal inflammation caused by high acidic
reflux; associated with GERD
Reflux Esophagitis Cause - Answers✔Gastric overdistention or poor LES tone
Hiatal Hernia Description - Answers✔Defect in diaphragm allowing a portion of the stomach to
pass through the diaphragmatic opening into the thorax
Ulcerative Colitis Description - Answers✔Chronic inflammatory disease of the mucosa of the
rectum and colon
Crohn Disease Affects - Answers✔Proximal portion of the colon or terminal ileum
Crohn Disease Description - Answers✔Chronic inflammation of all layers of intestinal wall
resulting from blockage and inflammation of lymphatic vessels
Antibiotic-Associated Colitis AKA - Answers✔Pseudomembranous Enterocolitis
Antibiotic-Associated Colitis Pathogenesis - Answers✔Clostridium difficile
Antibiotic-Associated Colits Rare Treatment - Answers✔Fecal transplant or colectomy
Diverticular Disease Description - Answers✔Presence of diverticula (herniations) in the colon
Volvulus Description - Answers✔Twisting of bowel on itself causing intestinal obstruction and
blood vessel compression (ischemia)
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Intussusception Description - Answers✔Telescoping/invagination of a portion of bowel into
adjacent (usually distal) bowel causing intestinal obstruction. Most often in infants.
Celiac Disease Description - Answers✔Familial intolerance of gluten-containing foods.
Leads to inflammation and atrophy of the intestinal villi
Celiac Disease Treatment - Answers✔Gluten free diet
Supplemental iron, folate, B12, fat soluble vitamins (A, D, E, K)
Oral corticosteriods or other immunomodulating agents for refractory
Colonic Polyps - Answers✔Any protrusion into the GI lumen
Major precursor lesion in development of colon cancer
Benign or malignant
Colon cancer - Answers✔Colonoscopy every 10 years
Hereditary - Familial adenomatous polyposis (FAP)
Cholecystitis Description - Answers✔Inflammation of the gallbladder wall
Acute Cholecystitis if left untreated - Answers✔Gangrene
Rupture
Peritonitis
Septic Shock
Localized abscess (empyema)
Cholecystoenteric fistula
Acute Cholecystitis Treatment - Answers✔Laproscopic cholecystectomy
Acute Pancreatitis Description - Answers✔Inflammation of the pancreas
Autodigestion of the pancreas from enzyme activation
Acute Pancreatitis Diagnosis - Answers✔Laboratory: lipase preferred test
Increase in amylase and lipase during first 12 hours
Elevated aminotransferases, alkaline phosphatase and bilirubin
CT of abdomen
Acute Pancreatitis Treatment - Answers✔Antibiotics for bacterial infection
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