Biochemistry
Cell Cycle Control And Cell Division Part 2
Compiled By Simon Mwangi
Edition: 2024/25
, Science | Biochemistry I of IV pages
1. G1/S checkpoint (1)
is the environment favorable?
2. pass G1/S checkpoint
enter cell cycle and proceed to S phase
3. G2M checkpoint (2)
is the DNA replicated?
is the environment favorable?
4. pass G2/M checkpoint
enter mitosis
5. metaphase to anaphase transition
are all chromosomes attached to the spindle?
6. pass metaphase to anaphase transition
trigger anaphase and proceed to cytokinesis
7. checkpoint controls (4)
late G1 or start checkpoint G2/M checkpointmetaphase to anaphase transition G0
8. the system is designed to through each of the checkpoints if problems are sensed
block progression
9. what is the G0 checkpoint associated with
dREAM complex
10. passage through the start checkpoint in late G1 launches
DNA replication and the S phase of the cell cycle
11. DNA replication occurs at specific sites or
origins of replications (AT rich regions)
12. what two steps is the initiation phase of DNA replication divided into?
late mitosis-early G1: prereplication complex assembles at the origins of replication onset of S phase when
13. the G2/M checkpoint ensures that
all of the DNA has been properly replicated
14. abrupt increases in M-cdk activity at the G2/M checkpoint drives (2)
entry into mitosis and the events of early mitosis
15. M-cdk induces (4)
assembly of the mitotic spindle chromosome condensationpromotes breakdown of the nuclear
16. each of the above events is triggered by mediated of specific proteins in conjugation with two other
Biochemistry 2024/25 Edition
Cell Cycle Control And Cell Division Part 2
Compiled By Simon Mwangi
Edition: 2024/25
, Science | Biochemistry I of IV pages
1. G1/S checkpoint (1)
is the environment favorable?
2. pass G1/S checkpoint
enter cell cycle and proceed to S phase
3. G2M checkpoint (2)
is the DNA replicated?
is the environment favorable?
4. pass G2/M checkpoint
enter mitosis
5. metaphase to anaphase transition
are all chromosomes attached to the spindle?
6. pass metaphase to anaphase transition
trigger anaphase and proceed to cytokinesis
7. checkpoint controls (4)
late G1 or start checkpoint G2/M checkpointmetaphase to anaphase transition G0
8. the system is designed to through each of the checkpoints if problems are sensed
block progression
9. what is the G0 checkpoint associated with
dREAM complex
10. passage through the start checkpoint in late G1 launches
DNA replication and the S phase of the cell cycle
11. DNA replication occurs at specific sites or
origins of replications (AT rich regions)
12. what two steps is the initiation phase of DNA replication divided into?
late mitosis-early G1: prereplication complex assembles at the origins of replication onset of S phase when
13. the G2/M checkpoint ensures that
all of the DNA has been properly replicated
14. abrupt increases in M-cdk activity at the G2/M checkpoint drives (2)
entry into mitosis and the events of early mitosis
15. M-cdk induces (4)
assembly of the mitotic spindle chromosome condensationpromotes breakdown of the nuclear
16. each of the above events is triggered by mediated of specific proteins in conjugation with two other
Biochemistry 2024/25 Edition
