Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
ib| ib| ib| ib| ib| ib| ib| ib| 1
Edition
Chapter 01: Drug Definitions, Standards, and Information Sources
ib| ib| ib| ib| ib| ib| ib|
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
ib| ib| ib| ib| ib| ib| ib| ib|
MULTIPLE CHOICE ib|
1. Which name identifies a drug listed by the US Food
ib| ib| ib| ib| ib| ib| ib| ib| ib|
and Drug Administration (FDA)?
ib| ib| ib| ib|
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C ib|
The official name is the name under which a drug is
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
listed by the FDA. The brand name, or trademark, is
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
the name given to a drug by its manufacturer. The
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
nonproprietary, or generic, name is provided by the
ib| ib| ib| ib| ib| ib| ib| ib|
United States Adopted Names Council.
ib| ib| ib| ib| ib|
DIF: Cognitive Level: Knowledge REF: p. 9 ib| ib| i b | ib|
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective
ib| ib| ib| ib| ib| ib| ib|
ib| Care Environment TOP:
ib| Nursing Process Step: Assessment ib| i b | ib| ib| ib|
CON:
ib| Patient Education ib|
2. Which source contains information specific to nutritional supplements?
ib| ib| ib| ib| ib| ib| ib|
a. USP Dictionary of USAN & International Drug Names
ib| ib| ib| ib | ib| ib| ib|
b. Natural Medicines Comprehensive Database ib| ib| ib|
c. United States Pharmacopoeia/National Formulary (USP NF)
ib| ib| ib| ib| ib|
d. Drug Interaction Facts ib| ib|
ANS: C ib|
United States Pharmacopoeia/National Formulary contains information specific to
ib| ib| ib| ib| ib| ib| ib|
nutritional supplements. USP Dictionary of USAN & International Drug Names is a
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
compilation of drug names, pronunciation guide, and possible future FDA approved
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
drugs; it does not include nutritional supplements. Natural Medicines Comprehensive
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
Database contains
ib| ib|
evidence-based information on herbal medicines and herbal combination products; it does
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
not include information specific to nutritional supplements. Drug Interaction Facts
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
contains comprehensive information on drug interaction facts; it does not include
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
nutritional supplements.
ib| ib|
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3 ib| ib| i b | ib| ib|
NAT: NCLEX Client Needs Category: Physiological Integrity
ib| i b | ib| ib| ib| ib| ib|
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
i b | ib| ib| ib| ib| ib| ib| ib|
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
a. Drug Facts and Comparisons ib| ib| ib|
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
ib| ib| ib| ib| ib| ib| ib| ib|
Edition
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
ib| ib| ib| ib| ib| ib| ib| ib| 2
Edition
b. Drug Interaction Facts ib| ib|
c. Handbook on Injectable Drugs ib| ib| ib|
d. Martindale—The Complete Drug Reference ib| ib| ib|
ANS: A ib|
Drug Facts and Comparisons contains drug monographs that describe all drugs
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
in a therapeutic class. Monographs are formatted as tables to allow comparison of
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
similar products, brand names, manufacturers, cost indices, and available dosage
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
forms Online version is available.
ib| ib| ib| ib| ib|
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 ib| ib| i b | ib| ib| ib|
OBJ: 3 i b |NAT: NCLEX Client Needs Category: Physiological Integrity
i b | ib| ib| ib| ib| ib| ib|
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
i b | ib| ib| ib| i b | ib| ib| ib| ib| ib| ib|
4. Which drug reference contains monographs about virtually every single-entity drug
ib| ib| ib| ib| ib| ib| ib| ib| ib|
available in the United States and describes therapeutic uses of drugs, including
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
approved and unapproved uses?
ib| ib| ib| ib|
a. Martindale: The Complete Drug Reference ib| ib| ib| ib|
b. AHFS Drug Information ib| ib|
c. Drug Reference ib|
d. Drug Facts and Comparisons ib| ib| ib|
ANS: B ib|
AHFS Drug Information contains monographs about virtually every single-entity drug
ib| ib| ib| ib| ib| ib| ib| ib| ib|
available in the United States and describes therapeutic uses of drugs, including approved
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
and unapproved uses.
ib| ib| ib|
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 ib| ib| i b | ib| ib| ib|
OBJ: 3 i b |NAT: NCLEX Client Needs Category: Physiological Integrity
i b | ib| ib| ib| ib| ib| ib|
TOP: Nursing Process Step: Planning CON: Safety | Patient Education | Clinical Judgment
i b | ib| ib| ib| i b | ib| ib| ib| ib| ib| ib|
5. Which online drug reference makes available to healthcare providers and the public a
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
standard, comprehensive, up-to-date look up and downloadable resource about
ib| ib| ib| ib| ib| ib| ib| ib| ib|
medicines?
ib|
a. American Drug Index ib| ib|
b. American Hospital Formulary ib| ib|
c. DailyMed
d. Drug Reference ib|
ANS: C ib|
DailyMed makes available to healthcare providers and the public a standard,
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
comprehensive, up-to-date look up and downloadable resource about medicines. The
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
American Drug Index is not appropriate for patient use. The American Hospital
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
Formulary is not appropriate for patient use. The drug reference is not appropriate for
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
patient use.
ib| ib|
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ: 3 ib| ib| i b | ib| ib| ib| ib| ib|
NAT: NCLEX Client Needs Category: Physiological Integrity
ib| i b | ib| ib| ib| ib| ib|
TOP: Nursing Process Step: Implementation
ib| ib| ib| ib|
CON: Safety | Patient Education | Clinical Judgment
i b | ib| ib| ib| ib| ib| ib|
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
a. Federal Food, Drug, and Cosmetic Act (1938) ib| ib| ib| ib| ib| ib|
b. Durham Humphrey Amendment (1952) ib| ib| ib|
i b |
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
ib| ib| ib| ib| ib| ib| ib| ib| ib|
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
ib| ib| ib| ib| ib| ib| ib| ib| 3
Edition
c. Controlled Substances Act (1970) ib| ib| ib|
d. Kefauver Harris Drug Amendment (1962) ib| ib| ib| ib|
ANS: A ib|
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
the safety of all drugs before marketing. Later amendments and acts helped tighten
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
FDA control and ensure drug safety. The Durham Humphrey Amendment defines the
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
kinds of drugs that cannot be used safely without medical supervision and restricts their
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
sale to prescription by a licensed practitioner. The Controlled Substances Act addresses
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
only controlled substances and their categorization. The Kefauver Harris Drug Amendment
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
ensures drug efficacy and greater drug safety. Drug manufacturers are required to prove
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
to the FDA the effectiveness of their products before marketing them.
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 ib| ib| i b | ib| ib| ib|
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological
i b | ib| ib| ib| ib| ib|
Integrity TOP: Nursing Process Step: Assessment
ib| ib| i b | ib| ib| ib|
CON: Safety | Patient Education | Evidence | Health Care Law
i b | ib| ib| ib| ib| ib| ib| ib| ib| ib|
7. Which classification does meperidine (Demerol) fall under?
ib| ib| ib| ib| ib| ib|
a. I
b. II
c. III
d. IV
ANS: B ib|
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
lead to severe psychological and physical dependence. Schedule I drugs have high
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
potential for abuse and no recognized medical use. Schedule III drugs have some
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
potential for abuse. Use may lead to low to moderate physical dependence or high
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
psychological dependence. Schedule IV drugs have low potential for abuse. Use may
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
lead to limited physical or psychological dependence.
ib| ib| ib| ib| ib| ib| ib|
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2 ib| ib| i b | ib| ib|
NAT: NCLEX Client Needs Category: Safe, Effective Care
ib| ib| ib| ib| ib| ib| ib| ib|
Environment
ib|
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
i b | ib| ib| ib| i b | ib| ib| ib| ib| ib|
8. Which action would the FDA take to expedite drug development and approval for an
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
ib| outbreak of smallpox? ib| ib|
a. List smallpox as a health orphan disease.
ib| ib| ib| ib| ib| ib|
b. Omit the preclinical research phase. ib| ib| ib| ib|
c. Extend the clinical research phase. ib| ib| ib| ib|
d. Fast track the investigational drug.
ib| ib| ib| ib|
ANS: D ib|
Once the Investigational New Drug Application has been approved, the drug can receive
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
highest priority within the agency, which is called fast tracking. A smallpox outbreak
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
would become a priority concern in the world. Orphan diseases are not researched in a
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
priority manner. Preclinical research is not omitted. Extending any phase of the research
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
would mean a longer time to develop a vaccine. The FDA must ensure that all phases of
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
the preclinical and clinical research phase have been completed in a safe manner.
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
DIF: Cognitive Level: Knowledge ib| ib| REF: ib| ib| p. 7 ib| OBJ: i b | 5
i b |
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
ib| ib| ib| ib| ib| ib| ib| ib| ib|
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
ib| ib| ib| ib| ib| ib| ib| ib| 4
Edition
NAT: NCLEX Client Needs Category: Safe, Effective Care
ib| ib| ib| ib| ib| ib| ib|
Environment TOP: Nursing Process Step: Assessment
ib| ib| i b | ib| ib| ib|
CON: Health Care Law | Health Care Policy | Infection | Care Coordination
i b | ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
9. Which statement is true about over-the-counter (OTC) drugs?
ib| ib| ib| ib| ib| ib| ib|
a. They are not listed in the USP NF.
ib| ib| ib| ib| ib| ib| ib|
b. A prescription from a healthcare provider is needed.
ib| ib| ib| ib| ib| ib| ib|
c. They are sold without a prescription.
ib| ib| ib| ib| ib|
d. They are known only by their brand names.
ib| ib| ib| ib| ib| ib| ib|
ANS: C ib|
OTC medications do not require a prescription. A variety of names, both generic and
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
trade, can be used for individual drugs sold OTC. OTC drugs are listed in the USP NF.
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
Prescription drugs require an order by a health professional who is licensed to
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
prescribe, such as a physician, nurse practitioner, physician assistant, or dentist.
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
DIF: Cognitive Level: Comprehension REF: p. 2 OBJ: 2 ib| ib| i b | ib| ib|
NAT: NCLEX Client Needs Category: Physiological Integrity
ib| i b | ib| ib| ib| ib| ib|
TOP: Nursing Process Step: Planning CON: Patient Education
i b | ib| ib| ib| i b | ib|
10. Which is the most authoritative reference for medications that are injected?
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
a. Martindale: The Complete ib| ib|
b. Handbook on Injectable Drugs ib| ib| ib|
c. DailyMed
d. Handbook of Nonprescription Drugs ib| ib| ib|
ANS: B ib|
The Handbook on Injectable Drugs is the most comprehensive reference available on
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
the topic of compatibility of injectable drugs. It is a collection of monographs for more
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
than 300 injectable drugs that are listed alphabetically by generic name.
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3 ib| ib| i b | ib| ib|
NAT: NCLEX Client Needs Category: Physiological Integrity
ib| i b | ib| ib| ib| ib| ib|
TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety
i b | ib| ib| ib| i b | ib| ib| ib|
11. Which statement is true about Lomotil?
ib| ib| ib| ib| ib|
a. Abuse potential for this drug is low. ib| ib| ib| ib| ib| ib|
b. Psychological dependency is likely. ib| ib| ib|
c. There is a high potential for abuse.
ib| ib| ib| ib| ib| ib|
d. This drug is not a controlled substance.
ib| ib| ib| ib| ib| ib|
ANS: A ib|
Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
dependence liability compared with drugs in Schedule IV. Because abuse potential is low
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
with a Schedule V drug, a prescription may not be required. Psychological dependency is
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
not likely with a Schedule V drug. Schedule V drugs are classified as controlled
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
substances.
ib|
DIF: Cognitive Level: Knowledge REF: p. 5 Box 1.1 ib| ib| i b | ib| ib| ib|
OBJ: 2 NAT: NCLEX Client Needs Category: Physiological
ib| ib| i b | ib| ib| ib| ib|
Integrity
ib|
TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety | Patient Education
i b | ib| ib| ib| i b | ib| ib| ib| ib| ib| ib|
ib| ib| ib| ib| ib| ib| ib| ib| 1
Edition
Chapter 01: Drug Definitions, Standards, and Information Sources
ib| ib| ib| ib| ib| ib| ib|
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
ib| ib| ib| ib| ib| ib| ib| ib|
MULTIPLE CHOICE ib|
1. Which name identifies a drug listed by the US Food
ib| ib| ib| ib| ib| ib| ib| ib| ib|
and Drug Administration (FDA)?
ib| ib| ib| ib|
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C ib|
The official name is the name under which a drug is
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
listed by the FDA. The brand name, or trademark, is
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
the name given to a drug by its manufacturer. The
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
nonproprietary, or generic, name is provided by the
ib| ib| ib| ib| ib| ib| ib| ib|
United States Adopted Names Council.
ib| ib| ib| ib| ib|
DIF: Cognitive Level: Knowledge REF: p. 9 ib| ib| i b | ib|
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective
ib| ib| ib| ib| ib| ib| ib|
ib| Care Environment TOP:
ib| Nursing Process Step: Assessment ib| i b | ib| ib| ib|
CON:
ib| Patient Education ib|
2. Which source contains information specific to nutritional supplements?
ib| ib| ib| ib| ib| ib| ib|
a. USP Dictionary of USAN & International Drug Names
ib| ib| ib| ib | ib| ib| ib|
b. Natural Medicines Comprehensive Database ib| ib| ib|
c. United States Pharmacopoeia/National Formulary (USP NF)
ib| ib| ib| ib| ib|
d. Drug Interaction Facts ib| ib|
ANS: C ib|
United States Pharmacopoeia/National Formulary contains information specific to
ib| ib| ib| ib| ib| ib| ib|
nutritional supplements. USP Dictionary of USAN & International Drug Names is a
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
compilation of drug names, pronunciation guide, and possible future FDA approved
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
drugs; it does not include nutritional supplements. Natural Medicines Comprehensive
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
Database contains
ib| ib|
evidence-based information on herbal medicines and herbal combination products; it does
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
not include information specific to nutritional supplements. Drug Interaction Facts
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
contains comprehensive information on drug interaction facts; it does not include
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
nutritional supplements.
ib| ib|
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3 ib| ib| i b | ib| ib|
NAT: NCLEX Client Needs Category: Physiological Integrity
ib| i b | ib| ib| ib| ib| ib|
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
i b | ib| ib| ib| ib| ib| ib| ib|
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
a. Drug Facts and Comparisons ib| ib| ib|
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
ib| ib| ib| ib| ib| ib| ib| ib|
Edition
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
ib| ib| ib| ib| ib| ib| ib| ib| 2
Edition
b. Drug Interaction Facts ib| ib|
c. Handbook on Injectable Drugs ib| ib| ib|
d. Martindale—The Complete Drug Reference ib| ib| ib|
ANS: A ib|
Drug Facts and Comparisons contains drug monographs that describe all drugs
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
in a therapeutic class. Monographs are formatted as tables to allow comparison of
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
similar products, brand names, manufacturers, cost indices, and available dosage
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
forms Online version is available.
ib| ib| ib| ib| ib|
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 ib| ib| i b | ib| ib| ib|
OBJ: 3 i b |NAT: NCLEX Client Needs Category: Physiological Integrity
i b | ib| ib| ib| ib| ib| ib|
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
i b | ib| ib| ib| i b | ib| ib| ib| ib| ib| ib|
4. Which drug reference contains monographs about virtually every single-entity drug
ib| ib| ib| ib| ib| ib| ib| ib| ib|
available in the United States and describes therapeutic uses of drugs, including
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
approved and unapproved uses?
ib| ib| ib| ib|
a. Martindale: The Complete Drug Reference ib| ib| ib| ib|
b. AHFS Drug Information ib| ib|
c. Drug Reference ib|
d. Drug Facts and Comparisons ib| ib| ib|
ANS: B ib|
AHFS Drug Information contains monographs about virtually every single-entity drug
ib| ib| ib| ib| ib| ib| ib| ib| ib|
available in the United States and describes therapeutic uses of drugs, including approved
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
and unapproved uses.
ib| ib| ib|
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 ib| ib| i b | ib| ib| ib|
OBJ: 3 i b |NAT: NCLEX Client Needs Category: Physiological Integrity
i b | ib| ib| ib| ib| ib| ib|
TOP: Nursing Process Step: Planning CON: Safety | Patient Education | Clinical Judgment
i b | ib| ib| ib| i b | ib| ib| ib| ib| ib| ib|
5. Which online drug reference makes available to healthcare providers and the public a
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
standard, comprehensive, up-to-date look up and downloadable resource about
ib| ib| ib| ib| ib| ib| ib| ib| ib|
medicines?
ib|
a. American Drug Index ib| ib|
b. American Hospital Formulary ib| ib|
c. DailyMed
d. Drug Reference ib|
ANS: C ib|
DailyMed makes available to healthcare providers and the public a standard,
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
comprehensive, up-to-date look up and downloadable resource about medicines. The
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
American Drug Index is not appropriate for patient use. The American Hospital
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
Formulary is not appropriate for patient use. The drug reference is not appropriate for
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
patient use.
ib| ib|
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ: 3 ib| ib| i b | ib| ib| ib| ib| ib|
NAT: NCLEX Client Needs Category: Physiological Integrity
ib| i b | ib| ib| ib| ib| ib|
TOP: Nursing Process Step: Implementation
ib| ib| ib| ib|
CON: Safety | Patient Education | Clinical Judgment
i b | ib| ib| ib| ib| ib| ib|
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
a. Federal Food, Drug, and Cosmetic Act (1938) ib| ib| ib| ib| ib| ib|
b. Durham Humphrey Amendment (1952) ib| ib| ib|
i b |
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
ib| ib| ib| ib| ib| ib| ib| ib| ib|
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
ib| ib| ib| ib| ib| ib| ib| ib| 3
Edition
c. Controlled Substances Act (1970) ib| ib| ib|
d. Kefauver Harris Drug Amendment (1962) ib| ib| ib| ib|
ANS: A ib|
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
the safety of all drugs before marketing. Later amendments and acts helped tighten
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
FDA control and ensure drug safety. The Durham Humphrey Amendment defines the
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
kinds of drugs that cannot be used safely without medical supervision and restricts their
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
sale to prescription by a licensed practitioner. The Controlled Substances Act addresses
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
only controlled substances and their categorization. The Kefauver Harris Drug Amendment
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
ensures drug efficacy and greater drug safety. Drug manufacturers are required to prove
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
to the FDA the effectiveness of their products before marketing them.
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 ib| ib| i b | ib| ib| ib|
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological
i b | ib| ib| ib| ib| ib|
Integrity TOP: Nursing Process Step: Assessment
ib| ib| i b | ib| ib| ib|
CON: Safety | Patient Education | Evidence | Health Care Law
i b | ib| ib| ib| ib| ib| ib| ib| ib| ib|
7. Which classification does meperidine (Demerol) fall under?
ib| ib| ib| ib| ib| ib|
a. I
b. II
c. III
d. IV
ANS: B ib|
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
lead to severe psychological and physical dependence. Schedule I drugs have high
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potential for abuse and no recognized medical use. Schedule III drugs have some
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potential for abuse. Use may lead to low to moderate physical dependence or high
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psychological dependence. Schedule IV drugs have low potential for abuse. Use may
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
lead to limited physical or psychological dependence.
ib| ib| ib| ib| ib| ib| ib|
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2 ib| ib| i b | ib| ib|
NAT: NCLEX Client Needs Category: Safe, Effective Care
ib| ib| ib| ib| ib| ib| ib| ib|
Environment
ib|
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
i b | ib| ib| ib| i b | ib| ib| ib| ib| ib|
8. Which action would the FDA take to expedite drug development and approval for an
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
ib| outbreak of smallpox? ib| ib|
a. List smallpox as a health orphan disease.
ib| ib| ib| ib| ib| ib|
b. Omit the preclinical research phase. ib| ib| ib| ib|
c. Extend the clinical research phase. ib| ib| ib| ib|
d. Fast track the investigational drug.
ib| ib| ib| ib|
ANS: D ib|
Once the Investigational New Drug Application has been approved, the drug can receive
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
highest priority within the agency, which is called fast tracking. A smallpox outbreak
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would become a priority concern in the world. Orphan diseases are not researched in a
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
priority manner. Preclinical research is not omitted. Extending any phase of the research
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
would mean a longer time to develop a vaccine. The FDA must ensure that all phases of
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the preclinical and clinical research phase have been completed in a safe manner.
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
DIF: Cognitive Level: Knowledge ib| ib| REF: ib| ib| p. 7 ib| OBJ: i b | 5
i b |
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
ib| ib| ib| ib| ib| ib| ib| ib| ib|
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
ib| ib| ib| ib| ib| ib| ib| ib| 4
Edition
NAT: NCLEX Client Needs Category: Safe, Effective Care
ib| ib| ib| ib| ib| ib| ib|
Environment TOP: Nursing Process Step: Assessment
ib| ib| i b | ib| ib| ib|
CON: Health Care Law | Health Care Policy | Infection | Care Coordination
i b | ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
9. Which statement is true about over-the-counter (OTC) drugs?
ib| ib| ib| ib| ib| ib| ib|
a. They are not listed in the USP NF.
ib| ib| ib| ib| ib| ib| ib|
b. A prescription from a healthcare provider is needed.
ib| ib| ib| ib| ib| ib| ib|
c. They are sold without a prescription.
ib| ib| ib| ib| ib|
d. They are known only by their brand names.
ib| ib| ib| ib| ib| ib| ib|
ANS: C ib|
OTC medications do not require a prescription. A variety of names, both generic and
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
trade, can be used for individual drugs sold OTC. OTC drugs are listed in the USP NF.
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
Prescription drugs require an order by a health professional who is licensed to
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
prescribe, such as a physician, nurse practitioner, physician assistant, or dentist.
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
DIF: Cognitive Level: Comprehension REF: p. 2 OBJ: 2 ib| ib| i b | ib| ib|
NAT: NCLEX Client Needs Category: Physiological Integrity
ib| i b | ib| ib| ib| ib| ib|
TOP: Nursing Process Step: Planning CON: Patient Education
i b | ib| ib| ib| i b | ib|
10. Which is the most authoritative reference for medications that are injected?
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
a. Martindale: The Complete ib| ib|
b. Handbook on Injectable Drugs ib| ib| ib|
c. DailyMed
d. Handbook of Nonprescription Drugs ib| ib| ib|
ANS: B ib|
The Handbook on Injectable Drugs is the most comprehensive reference available on
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
the topic of compatibility of injectable drugs. It is a collection of monographs for more
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
than 300 injectable drugs that are listed alphabetically by generic name.
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3 ib| ib| i b | ib| ib|
NAT: NCLEX Client Needs Category: Physiological Integrity
ib| i b | ib| ib| ib| ib| ib|
TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety
i b | ib| ib| ib| i b | ib| ib| ib|
11. Which statement is true about Lomotil?
ib| ib| ib| ib| ib|
a. Abuse potential for this drug is low. ib| ib| ib| ib| ib| ib|
b. Psychological dependency is likely. ib| ib| ib|
c. There is a high potential for abuse.
ib| ib| ib| ib| ib| ib|
d. This drug is not a controlled substance.
ib| ib| ib| ib| ib| ib|
ANS: A ib|
Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
dependence liability compared with drugs in Schedule IV. Because abuse potential is low
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
with a Schedule V drug, a prescription may not be required. Psychological dependency is
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
not likely with a Schedule V drug. Schedule V drugs are classified as controlled
ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib| ib|
substances.
ib|
DIF: Cognitive Level: Knowledge REF: p. 5 Box 1.1 ib| ib| i b | ib| ib| ib|
OBJ: 2 NAT: NCLEX Client Needs Category: Physiological
ib| ib| i b | ib| ib| ib| ib|
Integrity
ib|
TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety | Patient Education
i b | ib| ib| ib| i b | ib| ib| ib| ib| ib| ib|
