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NR 503 Midterm Exam(Complete solutions and resources for the course exam

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NR 503 Midterm Exam( Complete solutions and resources for the course examQuestion 1 Which of the following statements best describe efficacy? Question 2 A study is conducted for a pharmaceutical agent that has shown promise for reducing heart diseaseamong women. In order to more fully test the agent, an additional study is done restricting theparticipants to be r&omized to those who have a history of hypertension. Which of the followingadvantages cannot be claimed by the researchers? Question 3 What is the main advantage of the r&omization of the 168 study participants to one of thetwodrugtreatment groups? Question 4 After entry into the study, patients were first classified into three groups, those who had apreviousAMI, those with a first AMI who were at high risk for other cardiovascular diseases such as congestiveheart failure, & those with a first AMI who were at low risk for other cardiovascular diseases. Whichterm best describes the study design? Question 5 After assignment to treatment group, 77% of those in the placebo group were men, while80%ofthose in the drug X group were men. Which statement is most likely to be true? ONLYSTUDENTS STORE 2025 ALLLTHE BEST ONLYSTUDENTS STORE 2 DO NOT COPY • The characteristics of patients who failed to comply with the treatment dosages shouldbeassessed as they may differ from those who complied • Double blinding ensures that potential biases regarding selection, follow-up, &analysis canbereduced • Correct because the rate of death is decreased in the drug X group • R&omization was successful since the investigators did not alter the selection of participantsineither group in order to ensure equal percentages of men Question 6 A preliminary analysis was conducted after 6 months & found that 87% of participants in theplacebogroup & 85% of those in the drug X group had taken more than 90% of their prescribed dosages.Which statement best describes this finding? Question 7 Which of the following statements best describes the reason for conducting the study as adouble-blind trial? Question 8 A multicenter double-blind r&omized study was carried out to compare the effect of drug Xwiththatof a placebo in patients surviving acute myocardial infarction (AMI). Treatment with the drugstarted7days after infarction in 1,884 patients, 52% of all persons who were evaluated for entry intothestudy.945 participants were r&omized to treatment with drug X while 939 were assigned to the placebogroup. Patients were then followed for 12 months for reinfarction. There were 152 deaths intheplacebo group & 98 in the group receiving drug X. The researchers conclude that treatment with drug X reduces mortality in patients who havehadanAMI. The researchers are: Question 9 The following data come from a study of approaches to smoking cessation. Smokers who want toquitwere r&omized to one of four groups: control group C who received no intervention assistance, quitting guide group Q who received brochures about how to quit smoking, quitting guide&supportgroup QS who received quitting brochures as well as social support brochures listing benefits of smoking cessation, & telephone support group T who received the brochures & a monthly phonecallfrom a counselor. Participants received mailed surveys at 8, 16, & 24 months after r&omization. Theresults after 2 years are in the table below. Which group had the least success in terms of quitting ONLYSTUDENTS STORE 2025 ALLLTHE BEST ONLYSTUDENTS STORE 3 DO NOT COPY smoking? ONLYSTUDENTS STORE 2025 ALLLTHE BEST ONLYSTUDENTS STORE 4 DO NOT COPY • Group QS Question 1

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ONLYSTUDENTS STORE 2025 ALLLTHE BEST



NR 503 Midterm Exam
(Complete solutions and resources for the course exam)



Question 1
Which of the following statements best describe efficacy?


• It is an estimate of the benefit of treatment under ideal conditions
• It is an estimate of the reduction of disease in treated groups



Question 2
A study is conducted for a pharmaceutical agent that has shown promise for reducing heart disease
among women. In order to more fully test the agent, an additional study is done restricting the
participants to be r&omized to those who have a history of hypertension. Which of the following
advantages cannot be claimed by the researchers?


• The generalizability of the study is increased



Question 3
What is the main advantage of the r&omization of the 168 study participants to one of the two drug
treatment groups?



• Reduces the potential for selection bias in allocation of treatment group



Question 4
After entry into the study, patients were first classified into three groups, those who had a previous
AMI, those with a first AMI who were at high risk for other cardiovascular diseases such as congestive
heart failure, & those with a first AMI who were at low risk for other cardiovascular diseases. Which
term best describes the study design?

• R&omized clinical trial with stratified r&omization



Question 5
After assignment to treatment group, 77% of those in the placebo group were men, while 80% of
those in the drug X group were men. Which statement is most likely to be true?

ONLYSTUDENTS STORE 1 DO NOT COPY

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