Understanding Pathophysiology 7th edition by Huether, McCance Test BankL
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atest Updated Examination Study Guide 2022
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Understanding Pathophysiology 7th edition by Huether, McCance Test Bank
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Chapterg1.gCellulargBiology
MULTIPLEgCHOICE
1. Agstudentgisgobservinggagcellgundergthegmicroscope.gItgisgobservedgtoghavegsupercoiledgDNAg
withghistones.gWhichgofgthegfollowinggwouldgalsogbegobservedgbygthegstudent?
a. Agsinglegcirculargchromosome
b. Agnucleus
c. Free-floatinggnucleargmaterial
d. Nogorganelles
ANS:gB
Thegcellgdescribedgisgageukaryoticgcell,gsogitghasghistonesgandgagsupercoiledgDNAgwithingitsgn
ucleus;gthus,gthegnucleusgshouldgbegobserved.
Agsinglegcirculargchromosomegisgcharacteristicgofgprokaryoticgcells,gwhichgdognotghaveghistones.
Free-
floatinggnucleargmaterialgdescribesgagprokaryoticgcell,gwhichgwouldgnotghavegagdistinctgnucleus.
Eukaryoticgcellsghavegmembranegboundedgcellulargcomponentsgcalledgorganelles.gNogorganellesgd
escribesgagprokaryoticgcell.
2. Agnursegisginstructinggthegstaffgaboutgcellulargfunctions.gWhichgcellulargfunctiongisgthegnursegd
escribinggwhengangisolatedgcellgabsorbsgoxygengandgusesgitgtogtransformgnutrientsgtogenergy?
a. Metabolicgabsorption
b. Communication
c. Secretion
d. Respiration
,Understanding Pathophysiology 7th edition by Huether, McCance Test BankL
g g g g g g g g g
atest Updated Examination Study Guide 2022
g g g g g
ANS:gD
Thegabilitygofgthegcellgtogabsorbgoxygengrefersgtogthegcellsgfunctiongofgrespiration.
Thegabilitygofgthegcellgtogfunctiongwithingagsocietygofgcellsgrefersgtogitsgfunctiongofgc
ommunication.
Thegabilitygofgthegcellgtogtakegingnutrientsgrefersgtogthegcellsgfunctiongofgmetabolicgabsorption.
Thegabilitygofgthegcellgtogsynthesizegnewgsubstancesgandgsecretegthesegelsewheregrefersgtogthegcellsgf
unctiongofgsecretion.
3. AgeukaryoticgcellgisgundergoinggDNAgreplication.gIngwhichgregiongofgthegcellgwouldgmostgofgt
heggeneticginformationgbegcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus
ANS:gC
Thegregiongofgthegcellgthatgcontainsggeneticgmaterial,gincludinggaglargegamountgofgribonucleicga
cid,gmostgofgthegDNA,gandgDNA-bindinggproteins,gisgthegnucleolus.
Thegmitochondriagisgthegsitegofgcellulargrespiration.
Thegribosomesgareginvolvedgingmanufacturinggofgproteinsgwithingthegcell.
Thegnucleusgcontainsgthegnucleolus,gandgitgisgthegnucleolusgthatgcontainsggeneticgmaterial.
4. Thegfluidgmosaicgmodelgforgbiologicgmembranesgdescribesgmembranegbehavior.gAccordinggtogt
hisgmodel,gwhichgofgthegfollowinggfloatgsinglygorgasgaggregatesgingthegfluidglipidgbilayer?
a. Peripheralgmembranegproteins
b. Integralgmembranegproteins
,Understanding Pathophysiology 7th edition by Huether, McCance Test BankL
g g g g g g g g g
atest Updated Examination Study Guide 2022
g g g g g
c. Glycoproteins
d. Cellgadhesiongmolecules
ANS:gB
Integralgmembranegproteinsgfloatgfreelygingthegfluidglipidgbilayer.
Peripheralgmembranegproteinsgaregnotgembeddedgingtheglayer,gbutgresidegatgthegsurface.g
Glycoproteinsgactgasgcellgsurfacegmarkers.
Cellgadhesiongmoleculesgaregongthegoutsidegofgthegmembranegandgallowgcellsgtoghookgtogether.
5. Whichgofgthegfollowinggcangbindgtogplasmagmembranegreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicglipids
d. Ligands
ANS:gD
Ligandsgaregspecificgmoleculesgthatgcangbindgwithgreceptorsgongthegcellgmembrane.g
Oxygengmovesgbygdiffusion;gitgdoesgnotgbindgtogreceptors.
Ribosomesgmakegproteinsgandgaregnotginvolvedgingbinding.g
Amphipathicglipidsgaregagportiongofgthegcellgmembrane.
6. Agnursegisgreviewinggagreportgfromgagpatientgwithgmetastaticgcancer.gWhatgfindinggwouldgs
upportgthegdiagnosisgofgmetastaticgcancer?gAlterationsgingextracellulargmatrixgthatginclude:
a. Decreasedgfibronectin
b. Increasedgcollagen
c. Decreasedgelastin
, Understanding Pathophysiology 7th edition by Huether, McCance Test BankL
g g g g g g g g g
atest Updated Examination Study Guide 2022
g g g g g
d. Increasedgglycoproteins
ANS:gA
Reducedgamountsgofgfibronectingaregfoundgingsomegtypesgofgcancerousgcells,gallowinggcancergc
ellsgtogtravel,gorgmetastasize.
Collagengprovidesgstrength,gandgitsgbreakdowngisgassociatedgwithgosteoarthritis,gnotgcancer.
Elastingisgfoundgingtheglungsgandgallowsgtissuesgtogstretch;gitgisgnotgassociatedgwithgcancerousgc
ells.
Decreased,gnotgincreased,gglycoproteinsgaregassociatedgwithgcancerousgcells.
7. Whichgformgofgcellgcommunicationgisgusedgtogrelategtogothergcellsgingdirectgphysicalgcontact?
a. Cellgjunction
b. Gapgjunction
c. Desmosomes
d. Tightgjunctions
ANS:gA
Cellgjunctionsgholdgcellsgtogethergandgpermitgmoleculesgtogpassgfromgcellgtogcell.
Gapgjunctionsgallowgcommunicationgfromgtheginsidegofgonegcellgtogtheginsidegofganother.g
Desmosomesgaregnotginvolvedgingcommunication,gbutgallowgcellsgtogholdgtogether.
Tightgjunctionsgaregbarriersgthatgpreventgmovementgofgsomegsubstancesgandgleakagesgofgothers.
8. Pancreaticgbetagcellsgsecreteginsulin,gwhichginhibitsgsecretiongofgglucagongfromgneighboringga
lphagcells.gThisgactiongisgangexamplegofgwhichgofgthegfollowinggsignalinggtypes?
a. Paracrine
b. Autocrine
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atest Updated Examination Study Guide 2022
g g g g g
Understanding Pathophysiology 7th edition by Huether, McCance Test Bank
g g g g g g g g
Chapterg1.gCellulargBiology
MULTIPLEgCHOICE
1. Agstudentgisgobservinggagcellgundergthegmicroscope.gItgisgobservedgtoghavegsupercoiledgDNAg
withghistones.gWhichgofgthegfollowinggwouldgalsogbegobservedgbygthegstudent?
a. Agsinglegcirculargchromosome
b. Agnucleus
c. Free-floatinggnucleargmaterial
d. Nogorganelles
ANS:gB
Thegcellgdescribedgisgageukaryoticgcell,gsogitghasghistonesgandgagsupercoiledgDNAgwithingitsgn
ucleus;gthus,gthegnucleusgshouldgbegobserved.
Agsinglegcirculargchromosomegisgcharacteristicgofgprokaryoticgcells,gwhichgdognotghaveghistones.
Free-
floatinggnucleargmaterialgdescribesgagprokaryoticgcell,gwhichgwouldgnotghavegagdistinctgnucleus.
Eukaryoticgcellsghavegmembranegboundedgcellulargcomponentsgcalledgorganelles.gNogorganellesgd
escribesgagprokaryoticgcell.
2. Agnursegisginstructinggthegstaffgaboutgcellulargfunctions.gWhichgcellulargfunctiongisgthegnursegd
escribinggwhengangisolatedgcellgabsorbsgoxygengandgusesgitgtogtransformgnutrientsgtogenergy?
a. Metabolicgabsorption
b. Communication
c. Secretion
d. Respiration
,Understanding Pathophysiology 7th edition by Huether, McCance Test BankL
g g g g g g g g g
atest Updated Examination Study Guide 2022
g g g g g
ANS:gD
Thegabilitygofgthegcellgtogabsorbgoxygengrefersgtogthegcellsgfunctiongofgrespiration.
Thegabilitygofgthegcellgtogfunctiongwithingagsocietygofgcellsgrefersgtogitsgfunctiongofgc
ommunication.
Thegabilitygofgthegcellgtogtakegingnutrientsgrefersgtogthegcellsgfunctiongofgmetabolicgabsorption.
Thegabilitygofgthegcellgtogsynthesizegnewgsubstancesgandgsecretegthesegelsewheregrefersgtogthegcellsgf
unctiongofgsecretion.
3. AgeukaryoticgcellgisgundergoinggDNAgreplication.gIngwhichgregiongofgthegcellgwouldgmostgofgt
heggeneticginformationgbegcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus
ANS:gC
Thegregiongofgthegcellgthatgcontainsggeneticgmaterial,gincludinggaglargegamountgofgribonucleicga
cid,gmostgofgthegDNA,gandgDNA-bindinggproteins,gisgthegnucleolus.
Thegmitochondriagisgthegsitegofgcellulargrespiration.
Thegribosomesgareginvolvedgingmanufacturinggofgproteinsgwithingthegcell.
Thegnucleusgcontainsgthegnucleolus,gandgitgisgthegnucleolusgthatgcontainsggeneticgmaterial.
4. Thegfluidgmosaicgmodelgforgbiologicgmembranesgdescribesgmembranegbehavior.gAccordinggtogt
hisgmodel,gwhichgofgthegfollowinggfloatgsinglygorgasgaggregatesgingthegfluidglipidgbilayer?
a. Peripheralgmembranegproteins
b. Integralgmembranegproteins
,Understanding Pathophysiology 7th edition by Huether, McCance Test BankL
g g g g g g g g g
atest Updated Examination Study Guide 2022
g g g g g
c. Glycoproteins
d. Cellgadhesiongmolecules
ANS:gB
Integralgmembranegproteinsgfloatgfreelygingthegfluidglipidgbilayer.
Peripheralgmembranegproteinsgaregnotgembeddedgingtheglayer,gbutgresidegatgthegsurface.g
Glycoproteinsgactgasgcellgsurfacegmarkers.
Cellgadhesiongmoleculesgaregongthegoutsidegofgthegmembranegandgallowgcellsgtoghookgtogether.
5. Whichgofgthegfollowinggcangbindgtogplasmagmembranegreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicglipids
d. Ligands
ANS:gD
Ligandsgaregspecificgmoleculesgthatgcangbindgwithgreceptorsgongthegcellgmembrane.g
Oxygengmovesgbygdiffusion;gitgdoesgnotgbindgtogreceptors.
Ribosomesgmakegproteinsgandgaregnotginvolvedgingbinding.g
Amphipathicglipidsgaregagportiongofgthegcellgmembrane.
6. Agnursegisgreviewinggagreportgfromgagpatientgwithgmetastaticgcancer.gWhatgfindinggwouldgs
upportgthegdiagnosisgofgmetastaticgcancer?gAlterationsgingextracellulargmatrixgthatginclude:
a. Decreasedgfibronectin
b. Increasedgcollagen
c. Decreasedgelastin
, Understanding Pathophysiology 7th edition by Huether, McCance Test BankL
g g g g g g g g g
atest Updated Examination Study Guide 2022
g g g g g
d. Increasedgglycoproteins
ANS:gA
Reducedgamountsgofgfibronectingaregfoundgingsomegtypesgofgcancerousgcells,gallowinggcancergc
ellsgtogtravel,gorgmetastasize.
Collagengprovidesgstrength,gandgitsgbreakdowngisgassociatedgwithgosteoarthritis,gnotgcancer.
Elastingisgfoundgingtheglungsgandgallowsgtissuesgtogstretch;gitgisgnotgassociatedgwithgcancerousgc
ells.
Decreased,gnotgincreased,gglycoproteinsgaregassociatedgwithgcancerousgcells.
7. Whichgformgofgcellgcommunicationgisgusedgtogrelategtogothergcellsgingdirectgphysicalgcontact?
a. Cellgjunction
b. Gapgjunction
c. Desmosomes
d. Tightgjunctions
ANS:gA
Cellgjunctionsgholdgcellsgtogethergandgpermitgmoleculesgtogpassgfromgcellgtogcell.
Gapgjunctionsgallowgcommunicationgfromgtheginsidegofgonegcellgtogtheginsidegofganother.g
Desmosomesgaregnotginvolvedgingcommunication,gbutgallowgcellsgtogholdgtogether.
Tightgjunctionsgaregbarriersgthatgpreventgmovementgofgsomegsubstancesgandgleakagesgofgothers.
8. Pancreaticgbetagcellsgsecreteginsulin,gwhichginhibitsgsecretiongofgglucagongfromgneighboringga
lphagcells.gThisgactiongisgangexamplegofgwhichgofgthegfollowinggsignalinggtypes?
a. Paracrine
b. Autocrine