,The Molecular Biology of Cancer
PELEN: “fm” — 2006/3/7 — 16:36 — page i — #1
, Dedication
We would like to dedicate this work to our thank our daughter, Charlotte, for always loving
parents, whose support and encouragement us and helping us to maintain a balance between
throughout our lives, education, and subsequent work and private life and for being a constant
career development has been a major factor in reminder of the joy that family life can bring.
our success and peace of mind. We know that
Stella’s father, Andrew, who we recently lost to
us, would be especially proud of this. We also Mike Khan and Stella Pelengaris
ii
PELEN: “fm” — 2006/3/7 — 16:36 — page ii — #2
, The Molecular Biology
of Cancer
Edited by
Stella Pelengaris and Michael Khan
University of Warwick
With contributions from
Maria Blasco, Centro Nacional de Biotecnologia
Norbert C.J. de Wit, University of Warwick
Martine Roussel, St Jude Children’s Research Hospital
Nicky Rudd, University Hospitals of Leicester and LOROS Hospice
Christiana Ruhrberg, University College of London
David Shima, Cancer Research UK
William Steward, University of Leicester
Charles Streuli, University of Manchester
Anne Thomas, University of Leicester
Esther Waterhouse, University Hospitals of Leicester and LOROS Hospice
Cassian Yee, Fred Hutchinson Cancer Research Centre
Blackwell
Publishing
PELEN: “fm” — 2006/3/7 — 16:36 — page iii — #3
PELEN: “fm” — 2006/3/7 — 16:36 — page i — #1
, Dedication
We would like to dedicate this work to our thank our daughter, Charlotte, for always loving
parents, whose support and encouragement us and helping us to maintain a balance between
throughout our lives, education, and subsequent work and private life and for being a constant
career development has been a major factor in reminder of the joy that family life can bring.
our success and peace of mind. We know that
Stella’s father, Andrew, who we recently lost to
us, would be especially proud of this. We also Mike Khan and Stella Pelengaris
ii
PELEN: “fm” — 2006/3/7 — 16:36 — page ii — #2
, The Molecular Biology
of Cancer
Edited by
Stella Pelengaris and Michael Khan
University of Warwick
With contributions from
Maria Blasco, Centro Nacional de Biotecnologia
Norbert C.J. de Wit, University of Warwick
Martine Roussel, St Jude Children’s Research Hospital
Nicky Rudd, University Hospitals of Leicester and LOROS Hospice
Christiana Ruhrberg, University College of London
David Shima, Cancer Research UK
William Steward, University of Leicester
Charles Streuli, University of Manchester
Anne Thomas, University of Leicester
Esther Waterhouse, University Hospitals of Leicester and LOROS Hospice
Cassian Yee, Fred Hutchinson Cancer Research Centre
Blackwell
Publishing
PELEN: “fm” — 2006/3/7 — 16:36 — page iii — #3