NBME BIOCHEMISTRY 2024
SHELF EXAM
ANSWER ALL QUESTIONS IN THIS SECTION
QUESTION 1
What is amylo-4,6-transferase? - ANSWERS-branching enzyme for glycogen
synth
QUESTION 2
What enzyme can be both phosphorylated and attached to calcium ions to be
active? - ANSWERS-glycogen phosphorylase kinase
QUESTION 3
When is glycogen depleted in a fast? - ANSWERS-30 hr
QUESTION 4
When is gluconeogenesis the major pathway for energy? - ANSWERS-18-20 hr of
fast
END OF
PAGE 1
, NBME BIOCHEMISTRY 2024
SHELF EXAM
QUESTION 5
avidin, found in egg whites - ANSWERS-binds to biotin, decreases carboxylase
function
QUESTION 6
Cushing's syndrome - ANSWERS-^ glucocorticoids -> ^ PEPCK -> ^ PEP ->
hyperglycemia
QUESTION 7
Sly syndrome (mucopolysaccharidosis) - ANSWERS-def in beta-glucuronidase
QUESTION 8
classical galactosemia - ANSWERS-def in galactose 1-P uridylyltransferase; can
cause sepsis, hypoglycemia, phosphate sequestration
QUESTION 9
END OF
PAGE 2
, NBME BIOCHEMISTRY 2024
SHELF EXAM
symptoms of def in G6PDH - ANSWERS-hemolysis in oxidative environment
QUESTION 10
I-cell disease - ANSWERS-N-acetylglucosamine 1-P transferase; assoc with
gingival hypertrophy, devo delays
QUESTION 11
Conversion of glucose to sorbitol is accomplished by... - ANSWERS-aldose
reductase
QUESTION 12
Where are fatty acids synthesizedd? - ANSWERS-cytosol
QUESTION 13
What is an essential fatty acid? - ANSWERS-linoleate, diunsat FA
QUESTION 14
END OF
PAGE 3
SHELF EXAM
ANSWER ALL QUESTIONS IN THIS SECTION
QUESTION 1
What is amylo-4,6-transferase? - ANSWERS-branching enzyme for glycogen
synth
QUESTION 2
What enzyme can be both phosphorylated and attached to calcium ions to be
active? - ANSWERS-glycogen phosphorylase kinase
QUESTION 3
When is glycogen depleted in a fast? - ANSWERS-30 hr
QUESTION 4
When is gluconeogenesis the major pathway for energy? - ANSWERS-18-20 hr of
fast
END OF
PAGE 1
, NBME BIOCHEMISTRY 2024
SHELF EXAM
QUESTION 5
avidin, found in egg whites - ANSWERS-binds to biotin, decreases carboxylase
function
QUESTION 6
Cushing's syndrome - ANSWERS-^ glucocorticoids -> ^ PEPCK -> ^ PEP ->
hyperglycemia
QUESTION 7
Sly syndrome (mucopolysaccharidosis) - ANSWERS-def in beta-glucuronidase
QUESTION 8
classical galactosemia - ANSWERS-def in galactose 1-P uridylyltransferase; can
cause sepsis, hypoglycemia, phosphate sequestration
QUESTION 9
END OF
PAGE 2
, NBME BIOCHEMISTRY 2024
SHELF EXAM
symptoms of def in G6PDH - ANSWERS-hemolysis in oxidative environment
QUESTION 10
I-cell disease - ANSWERS-N-acetylglucosamine 1-P transferase; assoc with
gingival hypertrophy, devo delays
QUESTION 11
Conversion of glucose to sorbitol is accomplished by... - ANSWERS-aldose
reductase
QUESTION 12
Where are fatty acids synthesizedd? - ANSWERS-cytosol
QUESTION 13
What is an essential fatty acid? - ANSWERS-linoleate, diunsat FA
QUESTION 14
END OF
PAGE 3
