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Chapter 01: Drug Definitions, Standards, and Information Sources
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Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
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MULTIPLE
CHOICE
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1. Which name identifies a drug listed by the US
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Food andDrug Administration (FDA)?
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a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C nm
The official name is the name under which a drug is
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listed by the FDA. The brand name, or trademark, is
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the name given to a drug by its manufacturer. The
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nonproprietary, or generic, name is provided by the
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United States Adopted Names Council.
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DIF: Cognitive Level: Knowledge REF: p. 9 nm nm nm nm
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective
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Care Environment TOP:
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Patient Education
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2. Which source contains information specific to nutritional supplements?
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a. USP Dictionary of USAN & International Drug Names
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b. Natural Medicines Comprehensive Database nm nm nm
c. United States Pharmacopoeia/National Formulary (USP NF)
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d. Drug Interaction Facts nm nm
ANS: C nm
United States Pharmacopoeia/National Formulary contains information specific to
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nutritionalsupplements. USP Dictionary of USAN & International Drug Names is a
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compilation of drugnames, pronunciation guide, and possible future FDA approved
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drugs; it does not include nutritional supplements. Natural Medicines Comprehensive
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Database contains
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evidence-based information on herbal medicines and herbal combination products; it
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does notinclude information specific to nutritional supplements. Drug Interaction
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Facts contains comprehensive information on drug interaction facts; it does not
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include nutritional supplements.
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DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: nm nm n m nm
3 NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
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3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
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a. Drug Facts and Comparisons nm nm nm
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
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,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
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b. Drug Interaction Facts nm nm
c. Handbook on Injectable Drugs nm nm nm
d. Martindale—The Complete Drug Reference nm nm nm
ANS: A nm
Drug Facts and Comparisons contains drug monographs that describe all
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drugs in a therapeutic class. Monographs are formatted as tables to allow
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comparison of similarproducts, brand names, manufacturers, cost indices, and
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available dosage forms Online version is available.
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DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2nm nm n m nm nm nm
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
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4. Which drug reference contains monographs about virtually every single-entity drug
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availablein the United States and describes therapeutic uses of drugs, including
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approved and unapproved uses?
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a. Martindale: The Complete Drug Reference nm nm nm nm
b. AHFS Drug Information nm nm
c. Drug Reference nm
d. Drug Facts and Comparisons
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ANS: B nm
AHFS Drug Information contains monographs about virtually every single-entity drug
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available in the United States and describes therapeutic uses of drugs, including
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approved andunapproved uses.
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DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2nm nm n m nm nm nm
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Planning CON: Safety | Patient Education | Clinical Judgment
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5. Which online drug reference makes available to healthcare providers and the
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public a standard, comprehensive, up-to-date look up and downloadable resource
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about medicines?
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a. American Drug Index nm nm
b. American Hospital Formulary nm nm
c. DailyMed
d. Drug Reference nm
ANS: C nm
DailyMed makes available to healthcare providers and the public a standard,
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comprehensive,up-to-date look up and downloadable resource about medicines. The
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American Drug Index isnot appropriate for patient use. The American Hospital
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Formulary is not appropriate for patient use. The drug reference is not appropriate
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for patient use.
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DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ:
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3 NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Implementation
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CON: Safety | Patient Education | Clinical Judgment
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6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
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a. Federal Food, Drug, and Cosmetic Act (1938)
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b. Durham Humphrey Amendment (1952) nm nm nm
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,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
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c. Controlled Substances Act (1970) nm nm nm
d. Kefauver Harris Drug Amendment (1962) nm nm nm nm
ANS: A nm
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine
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the safety of all drugs before marketing. Later amendments and acts helped tighten
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FDA control and ensure drug safety. The Durham Humphrey Amendment defines the
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kinds of drugs that cannot be used safely without medical supervision and restricts
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their sale to prescription by a licensed practitioner. The Controlled Substances Act
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addresses only controlled substances andtheir categorization. The Kefauver Harris Drug
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Amendment ensures drug efficacy and greaterdrug safety. Drug manufacturers are
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required to prove to the FDA the effectiveness of their products before marketing
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them.
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DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 nm nm nm nm nm nm nm
OBJ: 5 n NAT: NCLEX Client Needs Category: Physiological
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Integrity TOP: Nursing Process Step: Assessment
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CON: Safety | Patient Education | Evidence | Health Care Law
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7. Which classification does meperidine (Demerol) fall under?
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a. I
b. II
c. III
d. IV
ANS: B nm
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and
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may lead to severe psychological and physical dependence. Schedule I drugs have
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high potential for abuseand no recognized medical use. Schedule III drugs have some
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potential for abuse. Use may lead to low to moderate physical dependence or high
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psychological dependence. Schedule IVdrugs have low potential for abuse. Use may
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lead to limited physical or psychological dependence.
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DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: nm nm n m nm
2 NAT: NCLEX Client Needs Category: Safe, Effective Care
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Environment
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TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
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8. Which action would the FDA take to expedite drug development and approval for an
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outbreakof smallpox?
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a. List smallpox as a health orphan disease.
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b. Omit the preclinical research phase.
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c. Extend the clinical research phase. nm nm nm nm
d. Fast track the investigational drug.
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ANS: D nm
Once the Investigational New Drug Application has been approved, the drug can
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receive highest priority within the agency, which is called fast tracking. A smallpox
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outbreak would become a priority concern in the world. Orphan diseases are not
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researched in a priority manner. Preclinical research is not omitted. Extending any
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phase of the research would meana longer time to develop a vaccine. The FDA must
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ensure that all phases of the preclinical andclinical research phase have been
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completed in a safe manner.
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DIF: Cognitive Level: Knowledge nm nm REF: n m p. 7 nm OBJ: 5 nm
nm Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
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Edition
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, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
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NAT: NCLEX Client Needs Category: Safe, Effective Care
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Environment TOP: Nursing Process Step: Assessment
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CON: Health Care Law | Health Care Policy | Infection | Care Coordination
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9. Which statement is true about over-the-counter (OTC) drugs?
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a. They are not listed in the USP NF.
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b. A prescription from a healthcare provider is needed.
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c. They are sold without a prescription.
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d. They are known only by their brand names.
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ANS: C nm
OTC medications do not require a prescription. A variety of names, both generic and
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trade, can be used for individual drugs sold OTC. OTC drugs are listed in the USP
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NF. Prescriptiondrugs require an order by a health professional who is licensed to
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prescribe, such as a physician, nurse practitioner, physician assistant, or dentist.
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DIF: Cognitive Level: Comprehension REF: p. 2 OBJ:nm nm n m nm
2 NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Planning CON: Patient Education
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10. Which is the most authoritative reference for medications that are injected?
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a. Martindale: The Complete nm nm
b. Handbook on Injectable Drugs nm nm nm
c. DailyMed
d. Handbook of Nonprescription Drugs nm nm nm
ANS: B nm
The Handbook on Injectable Drugs is the most comprehensive reference available on
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the topic of compatibility of injectable drugs. It is a collection of monographs for
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more than 300injectable drugs that are listed alphabetically by generic name.
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DIF: Cognitive Level: Knowledge REF: p. 4 OBJ:nm nm n m nm
3 NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety
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11. Which statement is true about Lomotil?
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a. Abuse potential for this drug is low.
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b. Psychological dependency is likely. nm nm nm
c. There is a high potential for abuse.
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d. This drug is not a controlled substance.
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ANS: A nm
Lomotil, a Schedule V drug, has an abuse potential of limited physical or
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psychological dependence liability compared with drugs in Schedule IV. Because abuse
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potential is low witha Schedule V drug, a prescription may not be required.
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Psychological dependency is not likelywith a Schedule V drug. Schedule V drugs are
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classified as controlled substances.
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DIF: Cognitive Level: Knowledge REF: p. 5 Box 1.1 nm nm n m nm nm nm
OBJ: 2 NAT: NCLEX Client Needs Category: Physiological
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Integrity
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TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety | Patient Education
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