and Answers 100% Pass
Under normal conditions, the _________________ response deters or
prevents disease. - ANSWER✔✔-immune
___________________________ an be defined as an abnormality in the
immune system that renders a person susceptible to diseases normally
prevented by an intact immune system. - ANSWER✔✔-Immunodeficiency
The ________________ immune system is composed of the phagocytic
leukocytes, natural killers cells and complement proteins. - ANSWER✔✔-
innate
The ________________ immune response is composed mainly of T and B
cells and responds to infections more slowly, but more specifically, than
the innate immune system. - ANSWER✔✔-adaptive
The adaptive immune system is further divided into the __________ and
__________ immune systems. - ANSWER✔✔-humoral, cellular
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,A large number of primary immunodeficiency diseases have been mapped
to the ________________ chromosome. - ANSWER✔✔-X
Defects in humoral immunity increases the risk of recurrent
_________________ infections. - ANSWER✔✔-pyogenic
During the first few months of life, infants are protected from infection by
IgG antibodies that originate in ________________ circulation during fetal
life. - ANSWER✔✔-maternal
Of all the primary immunodeficiency diseases, those affecting
___________________ production are the most frequent. - ANSWER✔✔-
antibody
Andormal immunoglobulin loss can occur with chronic _________________
disease; because of abnormal glomerular filtration, patients lose serum IgA
and IgG in their urine. - ANSWER✔✔-kidney
Secondary humoral immunodeficiencies can also result from a number of
____________________ including chronic lymphocytic leukemia,
lymphoma, and multiple myeloma that interfere with normal
immunoglobulin production. - ANSWER✔✔-malignancies
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, T cells can be functionally divided into two subtypes: __________________
and ___________________ T cells. - ANSWER✔✔-CD4+ helper, CD8+
cytotoxic
Collectively, _____________________ protect against fungal, protozoan,
viral, and intracellular bacterial infections; control malignant cell
proliferation; and are responsible for coordinating the overall immune
response. - ANSWER✔✔-T lymphocytes
Disorders that affect both B and T lymphocytes, with resultant defects in
both humoral and cell-mediated immunity, fall under the broad
classification of ________________ syndrome. - ANSWER✔✔-combined
immunodeficiency
In __________________, genetic mutations lead to absence of all T- and B-
cell function and, in some cases, a lack of NK cells. - ANSWER✔✔-severe
combined immunodeficiency (SCID)
SCID is more commonly found in _______________, as it is X linked. -
ANSWER✔✔-boys
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