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NSG 6420 MIDTERM EXAM STUDY GUIDE.

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©THESTAR EXAM SOLUTIONS 2024/2025 ALL RIGHTS RESERVED. 1 | P a g e NSG 6420 MIDTERM EXAM STUDY GUIDE. COPD Stage I - answerMILD FEV1/FVC 70% FEV1/80% *Chronic cough/sputum production *Pt unaware lung function is abnormal COPD Stage II - answerMODERATE FEV1/FVC 70% FEV1 50-80% SOB with exertion Cough and sputum production present COPD Stage III - answerSEVERE FEV1/FVC 70% FEV1 30-50% Greater SOB Reduced exercise capacity Fatigue Repeated exacerbations with impact on QOL COPD Stage IV - answerVERY SEVERE FEV1/FVC70% ©THESTAR EXAM SOLUTIONS 2024/2025 ALL RIGHTS RESERVED. 2 | P a g e FEV130% Resp. Failure Cor Pulmonale (elevation of JVP and pitting ankle edema) QOL very impaired Exacerbations may be life threatening How does FEV1 decrease? - answerInflammation Narrowing of peripheral airways Airway collapse in severe emphysema COPD diagnosis? - answerSPIROMETRY is key Primarily Inflammatory with superimposed bronchospasm - answerAsthma Most common chronic respiratory disorder among all age groups - answerAsthma Atophy - answerexaggerated IgE mediated immune response; all atophic disorders are type I hypersensitivity disorders Type I hypersensitivity reaction - answerImmediate hypersensitivity IgE-mediated Antigen binds to IgE that is bound to tissue mast cells and blood basophils, triggering release of preformed mediators (histamine, proteases, chemotactic factors) and synthesis of other mediators (prostaglandins, leukotrienes, platelet-activating factor, cytokines) -causes vasodilation, increased cap. permeability, mucus hypersecretion **atopic disorders (allergic asthma, rhinitis, conjunctivitis), anaphylaxis, some cases of angioedema, urticarial, and latex and some food allergies **Develop 1h after exposure to antigen Allergic triad of symptoms - answerallergies, eczema, and asthma Samter's Triad - answerNasal polyps, asthma, and ASA allergy Most common symptom of asthma - answerwheezing Common only symptom of asthma? - answerCough -can often delay dx of asthma

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NSG6420
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©THESTAR EXAM SOLUTIONS 2024/2025

ALL RIGHTS RESERVED.




NSG 6420 MIDTERM EXAM STUDY
GUIDE.

COPD Stage I - answer✔MILD
FEV1/FVC <70%
FEV1</80%
*Chronic cough/sputum production
*Pt unaware lung function is abnormal

COPD Stage II - answer✔MODERATE
FEV1/FVC <70%
FEV1 50-80%
SOB with exertion
Cough and sputum production present

COPD Stage III - answer✔SEVERE
FEV1/FVC < 70%
FEV1 30-50%
Greater SOB
Reduced exercise capacity
Fatigue
Repeated exacerbations with impact on QOL

COPD Stage IV - answer✔VERY SEVERE
FEV1/FVC<70%


1|Page

, ©THESTAR EXAM SOLUTIONS 2024/2025

ALL RIGHTS RESERVED.
FEV1<30%
Resp. Failure
Cor Pulmonale (elevation of JVP and pitting ankle edema)
QOL very impaired
Exacerbations may be life threatening

How does FEV1 decrease? - answer✔Inflammation
Narrowing of peripheral airways
Airway collapse in severe emphysema

COPD diagnosis? - answer✔SPIROMETRY is key

Primarily Inflammatory with superimposed bronchospasm - answer✔Asthma

Most common chronic respiratory disorder among all age groups - answer✔Asthma

Atophy - answer✔exaggerated IgE mediated immune response; all atophic disorders are type I
hypersensitivity disorders

Type I hypersensitivity reaction - answer✔Immediate hypersensitivity
IgE-mediated
Antigen binds to IgE that is bound to tissue mast cells and blood basophils, triggering release of
preformed mediators (histamine, proteases, chemotactic factors) and synthesis of other
mediators (prostaglandins, leukotrienes, platelet-activating factor, cytokines)
-causes vasodilation, increased cap. permeability, mucus hypersecretion
**atopic disorders (allergic asthma, rhinitis, conjunctivitis), anaphylaxis, some cases of
angioedema, urticarial, and latex and some food allergies
**Develop <1h after exposure to antigen

Allergic triad of symptoms - answer✔allergies, eczema, and asthma

Samter's Triad - answer✔Nasal polyps, asthma, and ASA allergy

Most common symptom of asthma - answer✔wheezing

Common only symptom of asthma? - answer✔Cough
-can often delay dx of asthma

2|Page

, ©THESTAR EXAM SOLUTIONS 2024/2025

ALL RIGHTS RESERVED.
AKA cough variant asthma

Best way to confirm asthma dx? - answer✔bronchial provocation

Intermittent asthma - answer✔sx </2days/week
PM awakenings </2/month
SABA use </2 days/week
No interference with norm. activity
0-1 exacerbations requiring oral steroids / yr

Tx for intermittent asthma - answer✔step 1

Mild asthma - answer✔Sx >/2days/week but not daily
pm awakenings 3-4x/month
SABA use >2 days/week but not daily
minor limitation

Intermittent asthma lung function - answer✔normal FEV1 bt exacerbations
FEV1>80% predicted
FEV1/FVC normal

Mild asthma lung function - answer✔FEV1>80% pred.
FEV1/FVC normal

Mild asthma tx - answer✔Step 2

Moderate asthma - answer✔Sx: daily
PM awakenings: >1x/week but not nightly
SABA use: daily
some limiation

mod. asthma lung function - answer✔60<FEV1<80 predicted
FEV1/FVC reduced 5%

Mod. asthma tx - answer✔step 3 and consider shot course of oral steroid

Severe asthma - answer✔Sx: thruout day

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