TEST BANK UNDERSTANDING PHARMACOLOGY: ESSENTIALS FOR MEDICATION
SAFETY, 2ND EDITION WORKMAN & LACHARITY
Absorption - (answer)Movement of a drug from the outside of the body into the blood stream.
Agonist - (answer)An extrinsic drug that activates the receptor site of a cell and mimics the actions of
naturally occurring drugs.
Antagonist - (answer)An extrinsic drug that blocks the receptor site of a cell, preventing the naturally
occurring substance from binding to the receptor.
Bioavailability - (answer)The percentage of a drug dose that actually reaches the blood.
Black Box Warning - (answer)A notice that a drug may produce serious or even life threatening effects in
some people in addition to its beneficial effects.
Cytoxic - (answer)A drug action that is intended to kill a cell or organism.
Distribution - (answer)The extent that a drug absorbed into the bloodstream spreads into the three body
water components.
Duration of Action - (answer)The length of time a drug is present in the blood at or above the level
needed to produce an effect or response.
Extrinsic Drugs - (answer)Drugs that are man made or derived from another species; not made by the
human body.
First pass loss - (answer)Rapid inactivation or elimination of oral drugs as a result of liver metabolism.
Generic Name - (answer)National and international public drug name created by the United States
Adopted NamesCouncil to indicate the usual use or chemical composition of a drug.
, Half Life - (answer)Time san needed for one half of a drug dose to be eliminated.
High Alert Drug - (answer)A drug that has an increased risk of causing patient harm if it is used in error.
Loading Dose - (answer)The first dose of a drug that is larger than all subsequent doses of the same
drug; used when it takes more drug to reach steady state that it does to maintain it.
Mechanism of Action - (answer)Exactly how, at the cellular level, a drug changes the activity of a cell.
Minimum Effective
Concentration - (answer)The smallest amount of drug necessary in the blood or target tissue to result in
a measurable intended action.
Percutaneous Route - (answer)Movement of a drug from the outside of the body to the inside through
the skin or mucous membranes.
Pharmacodynamics - (answer)Ways in which drugs work to change body function.
Pharmacokinetics - (answer)How the body changes drugs; drug metabolism.
Physiologic Effects - (answer)The change in body function as an income of the mechanism of action off a
drug.
Receptors - (answer)Physical place on or in a cell where a drug can bind and interact.
Sequestration - (answer)The trapping of drugs within certain body tissues, delaying their elimination and
extending their duration of action.
Steady State - (answer)Point at which drug elimination is balance with drug entry, resulting in a constant
effective blood level of the drug.
SAFETY, 2ND EDITION WORKMAN & LACHARITY
Absorption - (answer)Movement of a drug from the outside of the body into the blood stream.
Agonist - (answer)An extrinsic drug that activates the receptor site of a cell and mimics the actions of
naturally occurring drugs.
Antagonist - (answer)An extrinsic drug that blocks the receptor site of a cell, preventing the naturally
occurring substance from binding to the receptor.
Bioavailability - (answer)The percentage of a drug dose that actually reaches the blood.
Black Box Warning - (answer)A notice that a drug may produce serious or even life threatening effects in
some people in addition to its beneficial effects.
Cytoxic - (answer)A drug action that is intended to kill a cell or organism.
Distribution - (answer)The extent that a drug absorbed into the bloodstream spreads into the three body
water components.
Duration of Action - (answer)The length of time a drug is present in the blood at or above the level
needed to produce an effect or response.
Extrinsic Drugs - (answer)Drugs that are man made or derived from another species; not made by the
human body.
First pass loss - (answer)Rapid inactivation or elimination of oral drugs as a result of liver metabolism.
Generic Name - (answer)National and international public drug name created by the United States
Adopted NamesCouncil to indicate the usual use or chemical composition of a drug.
, Half Life - (answer)Time san needed for one half of a drug dose to be eliminated.
High Alert Drug - (answer)A drug that has an increased risk of causing patient harm if it is used in error.
Loading Dose - (answer)The first dose of a drug that is larger than all subsequent doses of the same
drug; used when it takes more drug to reach steady state that it does to maintain it.
Mechanism of Action - (answer)Exactly how, at the cellular level, a drug changes the activity of a cell.
Minimum Effective
Concentration - (answer)The smallest amount of drug necessary in the blood or target tissue to result in
a measurable intended action.
Percutaneous Route - (answer)Movement of a drug from the outside of the body to the inside through
the skin or mucous membranes.
Pharmacodynamics - (answer)Ways in which drugs work to change body function.
Pharmacokinetics - (answer)How the body changes drugs; drug metabolism.
Physiologic Effects - (answer)The change in body function as an income of the mechanism of action off a
drug.
Receptors - (answer)Physical place on or in a cell where a drug can bind and interact.
Sequestration - (answer)The trapping of drugs within certain body tissues, delaying their elimination and
extending their duration of action.
Steady State - (answer)Point at which drug elimination is balance with drug entry, resulting in a constant
effective blood level of the drug.
