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NSG124 / NSG 124 Exam 2 (NEW 2024 / 2025 Update): Pharmacology | Review with Questions and Verified Answers | 100% Correct | Graded A

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NSG124 / NSG 124 Exam 2 (NEW 2024 / 2025 Update): Pharmacology | Review with Questions and Verified Answers | 100% Correct | Graded A Three Classifications of Antimicrobials - ANSWERAntibacterial, Antifungal, Antiviral Three Classifications of Antimicrobials - ANSWERIdentity of Infection, Drug Sensitivity, and Host Factors Additive Response - ANSWERthe antimicrobial effect of the combination is equal to the sum of the effects of the two drugs alone Potentiative Interaction - ANSWERthe effect of the combination is greater than the sum of the effects of the individual agents. The most common systemic antifungals - ANSWERAmphotericin B and the Azole, Itraconazole. used to treat a broad spectrum of opportunistic and non-opportunistic mycoses infections. Adverse Effects of Itraconazole - ANSWERLike other azoles, itraconazole can inhibit drug-metabolizing enzymes and raise the levels of other drugs. GI reactions. Antagonism Response - ANSWERthe combination of two antibiotics may be less effective than one of the agents by itself. Appropriate Use of Antibiotics Prophylaxis - ANSWERSurgery, Bacterial Endocarditis, Neutropenia, reoccurring UTIs Inappropriate Use of Antibiotics Prophylaxis - ANSWERCommon cold, Bronchitis, Sore Throat, Sinusitis, Viral Infection, treatment of fever Penicillin- Mech. of Action - ANSWERweakens the cell wall, causing bacteria to take up excessive amounts of water and rupture. Beta-lactamases - ANSWERare enzymes that cleave the beta-lactam ring and thereby render penicillins and other beta-lactam antibiotics inactive. Narrow Spectrum Penicillin - Penicillinase sensitive - ANSWERPenicillin G Penicillin V Narrow Spectrum Penicillin - Penicillinase Resistant - ANSWERNafcillin, Oxacillin, Dicloxacillin Broad Spectrum Penicillin - ANSWERAmpicillin Amoxicillin Extended-Spectrum Penicillin - ANSWERPiperacillin Penicillin Allergy - ANSWERBecause of cross-sensitivity, patients allergic to one penicillin should be considered allergic to all other penicillins. In addition, a few patients (about 1%) display cross-sensitivity to cephalosporins. Penicillin Allergy Reaction - ANSWERObserve for 20-30 minutes after administration. Anaphylaxis (laryngeal edema, bronchoconstriction, severe hypotension). Nursing Considerations for Penicillin - ANSWERWatch for allergic reaction, assess therapeutic effects (fever reduction, pain, inflammation, etc), monitor kidney function, monitor for hyperkalemia.

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NSG124 / NSG 124 Exam 2 (NEW Update):
Pharmacology | Review with Questions and Verified Answers |
100% Correct | Graded A

Three Classifications of Antimicrobials - ANSWER>>Antibacterial, Antifungal, Antiviral


3 Principle Factors for choosing an Antibiotic - ANSWER>>Identity of Infection, Drug
Sensitivity, and Host Factors


Additive Response - ANSWER>>the antimicrobial effect of the combination is equal to
the sum of the effects of the two drugs alone


Potentiative Interaction - ANSWER>>the effect of the combination is greater than the
sum of the effects of the individual agents.


The most common systemic antifungals - ANSWER>>Amphotericin B and the Azole,
Itraconazole. used to treat a broad spectrum of opportunistic and non-opportunistic
mycoses infections.


Adverse Effects of Itraconazole - ANSWER>>Like other azoles, itraconazole can inhibit
drug-metabolizing enzymes and raise the levels of other drugs. GI reactions.


Antagonism Response - ANSWER>>the combination of two antibiotics may be less
effective than one of the agents by itself.


Appropriate Use of Antibiotics Prophylaxis - ANSWER>>Surgery, Bacterial
Endocarditis, Neutropenia, reoccurring UTIs


Inappropriate Use of Antibiotics Prophylaxis - ANSWER>>Common cold, Bronchitis,
Sore Throat, Sinusitis, Viral Infection, treatment of fever

, Penicillin- Mech. of Action - ANSWER>>weakens the cell wall, causing bacteria to take
up excessive amounts of water and rupture.


Beta-lactamases - ANSWER>>are enzymes that cleave the beta-lactam ring and
thereby render penicillins and other beta-lactam antibiotics inactive.


Narrow Spectrum Penicillin - Penicillinase sensitive - ANSWER>>Penicillin G
Penicillin V


Narrow Spectrum Penicillin - Penicillinase Resistant - ANSWER>>Nafcillin, Oxacillin,
Dicloxacillin


Broad Spectrum Penicillin - ANSWER>>Ampicillin
Amoxicillin


Extended-Spectrum Penicillin - ANSWER>>Piperacillin


Penicillin Allergy - ANSWER>>Because of cross-sensitivity, patients allergic to one
penicillin should be considered allergic to all other penicillins. In addition, a few
patients (about 1%) display cross-sensitivity to cephalosporins.


Penicillin Allergy Reaction - ANSWER>>Observe for 20-30 minutes after
administration. Anaphylaxis (laryngeal edema, bronchoconstriction, severe
hypotension).


Nursing Considerations for Penicillin - ANSWER>>Watch for allergic reaction, assess
therapeutic effects (fever reduction, pain, inflammation, etc), monitor kidney function,
monitor for hyperkalemia.

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