1. PEEP
ANSW recruits a certain number of collapsed alveoli
increases FRC & increases compliance in the dependent are (lower lobe) of lung
*compliance decreases in the non-dependent (upper lobe) area of the lung due tooverdistention
2. Indications of PEEP
ANSW Refractory Hypoxemia (will not respond to supplementalO2)
Shunt of >30%
Atelectasis with decreased FRC decreased
compliance
Certain disease processes
3. Goals of PEEP
ANSW enhance tissue oxygenation
maintain PaO2 >60 & SpO2 at or >90% @ acceptable pHRecruit alveoli & maintain
Restore FRC
4. Initiating PEEP
ANSW FIO2 >.50PIP >35 cwp
is PaO2 still <6
ANSW then start to increase PEEP by 3-5 unt
ANSW
1. acceptable oxygenation achieved
2. unacceptable side effects occur
ANSW
decreased compliance decreased
cardiac functionbarotrauma
5. Levels of PEEP
ANSW Minimum "physiologic" 3-5moderate 5-15
maximum >15
Optimal - PEEP level which achieves maximum benefits with least side effects
6. Physiologic Effects of PEEP on
ANSW
ANSW PaO2 - upFRC - up
PaCO2 - down BP -
down
1/3
, PEEP & CPAP
PvO2 - improves Intrapulmonary
shunt - downCardiac output - down
Ca-v O2 - down ICP -
up
Compliance - improves
7. ARDS causes
ANSW
ANSW decrease compliancedecrease FRC
increase PVR
2/3