6521 Advanced Pharmacology Week 1|
Complete Solutions| Module 1-5(Case
Study Set)
**Case Study 1**
A parent asks the nurse why ibuprofen is not recommended for infants under six months of age.
Which response by the nurse is correct?
"Infants have immature renal function, which makes it harder for them to eliminate ibuprofen
effectively."
---
**Case Study 2**
A nurse is caring for a 60-year-old patient with chronic kidney disease who has been prescribed
Metformin for type 2 diabetes. The patient asks why regular kidney function monitoring is
necessary. Which response by the nurse is correct?
"Metformin can accumulate in the body if the kidneys aren't functioning well, increasing the
risk of lactic acidosis."
---
**Case Study 3**
1
,A nurse notes that a patient taking codeine for pain reports that the medication has been
ineffective. The nurse suspects a genetic variation may be responsible. Which pharmacogenomic
explanation should the nurse provide to the patient?
"Some individuals lack the enzyme CYP2D6, which is needed to convert codeine into its
active form, making it ineffective for pain relief."
---
**Case Study 4**
A nurse is providing education to a patient who has recently been prescribed clopidogrel (Plavix)
after experiencing a stroke. The patient expresses concerns about why genetic testing was
suggested before starting the medication. Which explanation by the nurse is appropriate?
"Certain genetic variations can reduce your ability to metabolize clopidogrel effectively,
decreasing its protective effects against blood clots."
---
**Case Study 5**
A nurse caring for an elderly patient with hypertension notes that the patient has been prescribed
a beta-blocker. The patient reports feeling dizzy and tired. Which explanation by the nurse is
correct regarding beta-blocker pharmacokinetics in older adults?
"Older adults may have a slower metabolism and clearance of beta-blockers, which can cause
the medication to build up and lead to side effects like dizziness and fatigue."
2
,---
**Case Study 6**
Parents of a 4-year-old child ask why amoxicillin is prescribed instead of a stronger antibiotic for
an ear infection. Which response by the nurse is correct?
"Amoxicillin is effective against the most common bacteria that cause ear infections and is less
likely to lead to antibiotic resistance than stronger antibiotics."
---
**Case Study 7**
A nurse caring for a young adult patient with tuberculosis notes that the patient has developed
numbness and tingling in their extremities. Which question should the nurse ask when taking the
medication history to identify a potential cause?
"Are you taking isoniazid without vitamin B6 supplementation?"
---
**Case Study 8**
A nurse is caring for a pregnant woman diagnosed with a urinary tract infection (UTI). The
provider prescribes a course of Nitrofurantoin. The patient asks if this medication is safe for her
baby. What is the nurse’s correct response?
3
, "Nitrofurantoin is generally safe during most stages of pregnancy, but it’s usually avoided
near term due to the risk of hemolytic anemia in newborns with certain enzyme deficiencies."
---
**Case Study 9**
A parent asks the nurse why tetracycline is not recommended for children under 8 years old.
What is the nurse’s correct response?
"Tetracycline can bind to calcium in teeth and bones, causing permanent tooth discoloration
and affecting bone growth in young children."
---
**Case Study 10**
A nurse is caring for a patient who has a history of seizures and is prescribed phenytoin. The
patient is pregnant and concerned about the safety of this medication. Which explanation by the
nurse is accurate?
"Phenytoin can increase the risk of birth defects, so it’s important to discuss alternative
medications with your healthcare provider."
---
**Case Study 11**
4
Complete Solutions| Module 1-5(Case
Study Set)
**Case Study 1**
A parent asks the nurse why ibuprofen is not recommended for infants under six months of age.
Which response by the nurse is correct?
"Infants have immature renal function, which makes it harder for them to eliminate ibuprofen
effectively."
---
**Case Study 2**
A nurse is caring for a 60-year-old patient with chronic kidney disease who has been prescribed
Metformin for type 2 diabetes. The patient asks why regular kidney function monitoring is
necessary. Which response by the nurse is correct?
"Metformin can accumulate in the body if the kidneys aren't functioning well, increasing the
risk of lactic acidosis."
---
**Case Study 3**
1
,A nurse notes that a patient taking codeine for pain reports that the medication has been
ineffective. The nurse suspects a genetic variation may be responsible. Which pharmacogenomic
explanation should the nurse provide to the patient?
"Some individuals lack the enzyme CYP2D6, which is needed to convert codeine into its
active form, making it ineffective for pain relief."
---
**Case Study 4**
A nurse is providing education to a patient who has recently been prescribed clopidogrel (Plavix)
after experiencing a stroke. The patient expresses concerns about why genetic testing was
suggested before starting the medication. Which explanation by the nurse is appropriate?
"Certain genetic variations can reduce your ability to metabolize clopidogrel effectively,
decreasing its protective effects against blood clots."
---
**Case Study 5**
A nurse caring for an elderly patient with hypertension notes that the patient has been prescribed
a beta-blocker. The patient reports feeling dizzy and tired. Which explanation by the nurse is
correct regarding beta-blocker pharmacokinetics in older adults?
"Older adults may have a slower metabolism and clearance of beta-blockers, which can cause
the medication to build up and lead to side effects like dizziness and fatigue."
2
,---
**Case Study 6**
Parents of a 4-year-old child ask why amoxicillin is prescribed instead of a stronger antibiotic for
an ear infection. Which response by the nurse is correct?
"Amoxicillin is effective against the most common bacteria that cause ear infections and is less
likely to lead to antibiotic resistance than stronger antibiotics."
---
**Case Study 7**
A nurse caring for a young adult patient with tuberculosis notes that the patient has developed
numbness and tingling in their extremities. Which question should the nurse ask when taking the
medication history to identify a potential cause?
"Are you taking isoniazid without vitamin B6 supplementation?"
---
**Case Study 8**
A nurse is caring for a pregnant woman diagnosed with a urinary tract infection (UTI). The
provider prescribes a course of Nitrofurantoin. The patient asks if this medication is safe for her
baby. What is the nurse’s correct response?
3
, "Nitrofurantoin is generally safe during most stages of pregnancy, but it’s usually avoided
near term due to the risk of hemolytic anemia in newborns with certain enzyme deficiencies."
---
**Case Study 9**
A parent asks the nurse why tetracycline is not recommended for children under 8 years old.
What is the nurse’s correct response?
"Tetracycline can bind to calcium in teeth and bones, causing permanent tooth discoloration
and affecting bone growth in young children."
---
**Case Study 10**
A nurse is caring for a patient who has a history of seizures and is prescribed phenytoin. The
patient is pregnant and concerned about the safety of this medication. Which explanation by the
nurse is accurate?
"Phenytoin can increase the risk of birth defects, so it’s important to discuss alternative
medications with your healthcare provider."
---
**Case Study 11**
4
