Clinical Lab Final Exam
Utero infection - ANS Pregnant Pt with elevated IgM indicates what?
IgA1 - ANS IgA subtype mainly concentrated in serum
IgA2 - ANS IgA subtype mainly concentrated in secretions
IgA - ANS What antibody would be elevated in nephropathy, vasculitis (Henoch-Schonlein purpura),
AIDS, and hepatitis?
IgA - ANS What antibody would be low in leukemia and macroglobulinemia?
Celiac Disease - ANS IgA sensitivity to gluten
Henoch-Schonlein Purpura - ANS Systemic disorder usually in small children after a URI caused by
deposits of IgA and complement 3 (C3) in the small vessels
Vancomycin - ANS What antibiotic would cause a linear IgA dermatosis?
IgD - ANS Signals B cells activation/suppression and stimulates IgM
IgD - ANS What antibody is elevated in atopic dermatitis, asthma, immunodeficiency, parasitic
infections, viral infections, chronic inflammatory diseases, cancer?
Delayed-typed Hypersensitivity T Cells - ANS Immune cell that secretes macrophage chemotaxis
,Plasma Cell - ANS Long, non-proliferating antibody-secreting cell arising from B cell differentiation
IL-1 - ANS Immune secretion that stimulates T cell growth
IL-6 - ANS Immune secretion stimulates B cell growth
5-15 days - ANS In a primary response, how long does it take IgM to be synthesized?
2-4 days - ANS In a secondary response, how long does it take IgG to be synthesized?
Type I - ANS Hypersensitivity that ranges from intolerance to anaphylaxis
IgE - ANS Antibody associated with Type I hypersensitivity
Type II - ANS Hypersensitivity that is antibody-dependent
IgM, IgG, Complement Protein - ANS Components involved in Type II Hypersensitivity
Type II - ANS Goodpasture Syndrome, Grave's Disease, Autoimmune hemolytic anemia, and immune
thrombocytopenia are examples of which Hypersensitivity?
Type III - ANS Hypersensitivity where antibodies form an immune complex around soluble antigen
IgG, IgM, Complement Proteins, Neutrophils - ANS Components involved in Type III Hypersensitivity
, Type III - ANS SLE, RA, post strepto. glomerulonephritis, Serum sickness are examples of which
Hypersensitivity?
Type IV - ANS Delayed hypersensitivity mediated by Helper Ts and Memory Ts
Type IV - ANS Allergic contact dermatitis, DM I, chronic transplant rejection, and IBD are examples of
which hypersensitivity?
Cold agglutinin - ANS IgM agglutination leading to lysis
Donath-Landsteiner - ANS IgG cold agglutinin disease that causes cell lysis and flank pain w/ dark urine
Cryoglobulin - ANS Cold agglutinin that causes vasculitis and vascular occlusion
Primary Cold Agglutinin Disease - ANS Chronic disease of bone marrow that produces an autoantibody
that reacts at temperatures greater than 30 C and is usually an IgM antibody that is almost always anti-I
Hemolytic anemia
Secondary Cold Agglutinin Syndrome - ANS Cold agglutinin caused by M. pneumoniae or EBV.
Arthrus Reaction - ANS An intense Type III reaction at the site of injection of some antigen
B cell immunodeficiency - ANS Bruton's agammaglobulinemia and hypogammaglobulinemia are
examples of _____
T Cell immunodeficiency - ANS DiGeorge Syndrome is an example of ______
Utero infection - ANS Pregnant Pt with elevated IgM indicates what?
IgA1 - ANS IgA subtype mainly concentrated in serum
IgA2 - ANS IgA subtype mainly concentrated in secretions
IgA - ANS What antibody would be elevated in nephropathy, vasculitis (Henoch-Schonlein purpura),
AIDS, and hepatitis?
IgA - ANS What antibody would be low in leukemia and macroglobulinemia?
Celiac Disease - ANS IgA sensitivity to gluten
Henoch-Schonlein Purpura - ANS Systemic disorder usually in small children after a URI caused by
deposits of IgA and complement 3 (C3) in the small vessels
Vancomycin - ANS What antibiotic would cause a linear IgA dermatosis?
IgD - ANS Signals B cells activation/suppression and stimulates IgM
IgD - ANS What antibody is elevated in atopic dermatitis, asthma, immunodeficiency, parasitic
infections, viral infections, chronic inflammatory diseases, cancer?
Delayed-typed Hypersensitivity T Cells - ANS Immune cell that secretes macrophage chemotaxis
,Plasma Cell - ANS Long, non-proliferating antibody-secreting cell arising from B cell differentiation
IL-1 - ANS Immune secretion that stimulates T cell growth
IL-6 - ANS Immune secretion stimulates B cell growth
5-15 days - ANS In a primary response, how long does it take IgM to be synthesized?
2-4 days - ANS In a secondary response, how long does it take IgG to be synthesized?
Type I - ANS Hypersensitivity that ranges from intolerance to anaphylaxis
IgE - ANS Antibody associated with Type I hypersensitivity
Type II - ANS Hypersensitivity that is antibody-dependent
IgM, IgG, Complement Protein - ANS Components involved in Type II Hypersensitivity
Type II - ANS Goodpasture Syndrome, Grave's Disease, Autoimmune hemolytic anemia, and immune
thrombocytopenia are examples of which Hypersensitivity?
Type III - ANS Hypersensitivity where antibodies form an immune complex around soluble antigen
IgG, IgM, Complement Proteins, Neutrophils - ANS Components involved in Type III Hypersensitivity
, Type III - ANS SLE, RA, post strepto. glomerulonephritis, Serum sickness are examples of which
Hypersensitivity?
Type IV - ANS Delayed hypersensitivity mediated by Helper Ts and Memory Ts
Type IV - ANS Allergic contact dermatitis, DM I, chronic transplant rejection, and IBD are examples of
which hypersensitivity?
Cold agglutinin - ANS IgM agglutination leading to lysis
Donath-Landsteiner - ANS IgG cold agglutinin disease that causes cell lysis and flank pain w/ dark urine
Cryoglobulin - ANS Cold agglutinin that causes vasculitis and vascular occlusion
Primary Cold Agglutinin Disease - ANS Chronic disease of bone marrow that produces an autoantibody
that reacts at temperatures greater than 30 C and is usually an IgM antibody that is almost always anti-I
Hemolytic anemia
Secondary Cold Agglutinin Syndrome - ANS Cold agglutinin caused by M. pneumoniae or EBV.
Arthrus Reaction - ANS An intense Type III reaction at the site of injection of some antigen
B cell immunodeficiency - ANS Bruton's agammaglobulinemia and hypogammaglobulinemia are
examples of _____
T Cell immunodeficiency - ANS DiGeorge Syndrome is an example of ______
