CMN 574 Unit 1 Exam Questions And 100% Correct
Answers (A+ Graded)
Measure of the rate of fall of red blood cells in anticoagulated blood within a vertical
tube; reflects level of rouleaux formation caused by acute phase reactants - Answer
ESR
Synthesized by the liver; assists in clearance of pathologic bacteria and damaged cells
via activation of complement-mediated phagocytosis; mediates acute inflammation by
altering cytokine release and is thought to prevent autoimmunity by binding to and
masking autoantigens. - Answer CRP
CRP:
Most active phases of rheumatic disease result in elevation to __-__mg/dL.
Level >__mg/dL raises concern for bacterial infection or systemic vasculitis - Answer
1-10; 10
Definition of arthritis: Joint swelling or limitation/tenderness upon range of motion
(ROM), lasting ≥ __ weeks and not due to other identifiable cause - Answer 6
JRA or JIA: Children may not present with joint pain/swelling but other symptoms, such
as: - Answer morning stiffness, limp, refusal to walk, irritability, poor growth, or limb
discrepancy.
Uveitis
Development of uveitis is often insidious and asymptomatic, so routine pediatric
ophthalmology screening is required for children with JIA:
a. At diagnosis: First ophthalmologic examination should be within __ month.
,b. Active disease: Ophthalmologic examination every __ months, regardless of ANA
status. - Answer 1; 3
Definition: Diverse group of inflammatory arthritides that follow a bacterial or viral
infection, particularly involving respiratory, gastrointestinal (GI), and genitourinary
tracts.
Onset: Infection typically precedes development of arthritis by 1-4 weeks; ≈80% of
cases are preceded by gastroenteritis - Answer Reactive Arthritis
What are first-line drugs in the managment of arthritis? - Answer NSAIDS
What drugs can be given to slow disease progression of RA? - Answer DMARDS
Methotrexate: Side Effects and Recommended surveillance - Answer Abdominal
discomfort, nausea, liver toxicity, bone marrow toxicity, teratogenic
Baseline CMP Q2-3 mo
Hydroxychloroquine: Side Effects and Recommended Surveillance - Answer Retinal
toxicity
Ophthalmologic monitoring Q6 mo
Sulfasalazine: Side Effects and Recommended Surveillance - Answer Hematologic
toxicity, hepatic toxicity
CBC with differential, liver enzymes and urinalysis Q2-3 mo , IgG levels Q6 mo
, Leflunomide (DMARD): Side Effects and Recommended Surveillance - Answer Hepatic
toxicity, hematologic, mucositis, teratogenic, neuropathy
Baseline CBC and LFTs monthly for 6 mo, then Q8-12 wk
S/S of SLE - Answer Discoid rash - Erythematous raised patches with adherent keratotic
scaling and follicular plugging; atrophic scarring may occur in older lesions
Photosensitivity- Rash due to unusual reaction to sunlight (by patient history or
physician observation)
Oral ulcers- Oral or nasopharyngeal ulceration, usually painless, observed by physician
Nonerosive arthritis- Involving two or more peripheral joints, characterized by
tenderness, swelling, or effusion
Pleuritis or pericarditis
1. Pleuritis: history of pleuritic pain or rubbing heard by physician, or evidence of pleural
effusion
AND/OR
2. Pericarditis: documented by electrocardiogram or rub or evidence of pericardial
effusion
Renal disorder
1. Persistent proteinuria > 0.5 g/day or > 3+ if quantitation not performed
AND/OR
2.Cellular casts: may be red cell, hemoglobin, granular, tubular, or mixed
Neurologic disorder- Seizures or psychosis: in the absence of offending drugs,
hypertension, or known metabolic derangements
Answers (A+ Graded)
Measure of the rate of fall of red blood cells in anticoagulated blood within a vertical
tube; reflects level of rouleaux formation caused by acute phase reactants - Answer
ESR
Synthesized by the liver; assists in clearance of pathologic bacteria and damaged cells
via activation of complement-mediated phagocytosis; mediates acute inflammation by
altering cytokine release and is thought to prevent autoimmunity by binding to and
masking autoantigens. - Answer CRP
CRP:
Most active phases of rheumatic disease result in elevation to __-__mg/dL.
Level >__mg/dL raises concern for bacterial infection or systemic vasculitis - Answer
1-10; 10
Definition of arthritis: Joint swelling or limitation/tenderness upon range of motion
(ROM), lasting ≥ __ weeks and not due to other identifiable cause - Answer 6
JRA or JIA: Children may not present with joint pain/swelling but other symptoms, such
as: - Answer morning stiffness, limp, refusal to walk, irritability, poor growth, or limb
discrepancy.
Uveitis
Development of uveitis is often insidious and asymptomatic, so routine pediatric
ophthalmology screening is required for children with JIA:
a. At diagnosis: First ophthalmologic examination should be within __ month.
,b. Active disease: Ophthalmologic examination every __ months, regardless of ANA
status. - Answer 1; 3
Definition: Diverse group of inflammatory arthritides that follow a bacterial or viral
infection, particularly involving respiratory, gastrointestinal (GI), and genitourinary
tracts.
Onset: Infection typically precedes development of arthritis by 1-4 weeks; ≈80% of
cases are preceded by gastroenteritis - Answer Reactive Arthritis
What are first-line drugs in the managment of arthritis? - Answer NSAIDS
What drugs can be given to slow disease progression of RA? - Answer DMARDS
Methotrexate: Side Effects and Recommended surveillance - Answer Abdominal
discomfort, nausea, liver toxicity, bone marrow toxicity, teratogenic
Baseline CMP Q2-3 mo
Hydroxychloroquine: Side Effects and Recommended Surveillance - Answer Retinal
toxicity
Ophthalmologic monitoring Q6 mo
Sulfasalazine: Side Effects and Recommended Surveillance - Answer Hematologic
toxicity, hepatic toxicity
CBC with differential, liver enzymes and urinalysis Q2-3 mo , IgG levels Q6 mo
, Leflunomide (DMARD): Side Effects and Recommended Surveillance - Answer Hepatic
toxicity, hematologic, mucositis, teratogenic, neuropathy
Baseline CBC and LFTs monthly for 6 mo, then Q8-12 wk
S/S of SLE - Answer Discoid rash - Erythematous raised patches with adherent keratotic
scaling and follicular plugging; atrophic scarring may occur in older lesions
Photosensitivity- Rash due to unusual reaction to sunlight (by patient history or
physician observation)
Oral ulcers- Oral or nasopharyngeal ulceration, usually painless, observed by physician
Nonerosive arthritis- Involving two or more peripheral joints, characterized by
tenderness, swelling, or effusion
Pleuritis or pericarditis
1. Pleuritis: history of pleuritic pain or rubbing heard by physician, or evidence of pleural
effusion
AND/OR
2. Pericarditis: documented by electrocardiogram or rub or evidence of pericardial
effusion
Renal disorder
1. Persistent proteinuria > 0.5 g/day or > 3+ if quantitation not performed
AND/OR
2.Cellular casts: may be red cell, hemoglobin, granular, tubular, or mixed
Neurologic disorder- Seizures or psychosis: in the absence of offending drugs,
hypertension, or known metabolic derangements
