WGUlD441l(LatestlUpdate)lMedicallDosagel
CalculationslandlPharmacology |Qsl&lAs|l
100%lCorrect|lGradelAl(VerifiedlAnswers)
Q:lWhichlanxiolyticldruglpromoteslantagonisticlactivitylatlbothlthelserotoninlandldopaminelre
ceptors?
1.lBuspirone
2.lAlprazolam
3.lLorazepam
4.lAmitriptyline
Answer:
1.lBuspironelislanlanxiolyticldrug,lwhichlhaslagonistlactivitylatlbothlthelserotoninlandldopamin
elreceptorsltolexertlitslantianxietyleffect.lAlprazolamlislalbenzodiazepinelthatlislcommonlylused
laslanlanxiolytic.lTheldruglelicitslitsleffectslbylincreasinglthelactivityloflgamma-
aminobutyriclacidl(GABA)lreceptorslthatlblocklnerveltransmissionlinlthelcentrallnervouslsyste
m.lLorazepamlislanlintermediate-
actinglbenzodiazepinelthatlincreaseslthelactivityloflthelGABAlreceptors.lAmitriptylinelislthelm
ostlcommonlylusedltricycliclantidepressant.
Q:lAlpatientldiagnosedlwithlanlanxietyldisorderlhaslbeenlusingllorazepamlbutlfindslthelsidele
ffectlofldrowsinessltolbelinterferinglwithllife.lWhichlanxiolyticlmedicationslmightlbelalbetterlo
ptionlforlthislpatient?
1.lBuspirone
2.lAlprazolam
3.lChlordiazepoxide
4.lHydroxyzinelhydrochloridelsalt
Answer:
1.lBuspironelislalthird-
generationlanxiolyticlthatlhasltheladvantageloflbeinglbothlnonsedatinglandlnon-habit-
forming.lAlprazolam,lchlordiazepoxide,landlhydroxyzinelhydrochloridelsaltlarelsedativeslaslwel
llaslanxiolytics.
,Q:lAlpatientlwholhasldepressionlislprescribedlduloxetine.lWhichltestslwilllthelnurselsuggestlt
olthelproviderlbeforeltheltherapylislstarted?
1.lRenallfunctionltest
2.lLiverlfunctionltest
3.lCompletelbloodlcount
4.lCompletelurinelexamination
Answer:
2.lDuloxetineltendsltolcauselliverltoxicity;lthereforelalliverlfunctionltestlshouldlbeldonelbeforel
startingltheltherapy.lRenallfunctionltestslmaylnotlbelimportantlbecauseltheldrugldoeslnotlaffectlt
helfunctionloflthelkidneys.lCompletelbloodlcountlandlurinelexaminationlareldoneltolgetlbaselin
elvaluesloflthelbiochemicallparameters,lbutltheselarelnotlimportantltoldeterminelthelprogresslofl
theltherapy.
Q:lAlpatientlwithlattentionldeficitlhyperactivityldisorderlislprescribedlanloralldoselofldiazepa
m.lWhatlislthelmaximumldoselofltheldruglthatlthelpatientlwouldlreceivelinlalday?lRecordlyourl
answerlusinglalwholelnumber.l_____lmglofldiazepamlperlday40
Answer:
30
Theloralldoselofldiazepamlforlalpatientlisl2ltol10lmgltwoltolthreeltimeslperlday.lThereforelthel
maximumldoselofltheldruglthelpatientlwouldlreceivelinlaldaylwouldlbel10lmgl×l3ltimesl=l30lm
g/day.
Q:lWhichlmood-stabilizingldrugslarelusedltoltreatlbipolarldisorder?lSelectlalllthatlapply.
1.lBupropion
2.lImipramine
3.lIsocarboxazid
4.lOxcarbazepine
5.lLithiumlcarbonate
Answer:
4,l5
,Moodlstabilizerslareldrugslthatlarelusedltoltreatlthelcyclesloflmania,lhypomania,landldepression
lbylregulatinglthelmetabolismloflcatecholamines.lExamplesloflmoodlstabilizerslincludeloxcarba
zepinelandllithiumlcarbonate.lImipraminelislaltricycliclantidepressant,lnotlalmoodlstabilizer.lItli
slalsecond-
lineltherapeuticldruglforlbipolarldisorders.lBupropionlislaldruglthatlislcategorizedlunderlalmisce
llaneouslgrouplandlislusedlforltheltreatmentlofldepression.lIsocarboxazidlislalmonoamineloxida
selinhibitorlusedlforltheltreatmentlofldepression.
Q:lThelnurselislassessinglalpatientlwholislprescribedlalbenzodiazepine.lWhenlreviewinglthelp
atient'slhistory,lwhatlmaylthelnurselask?
1.l"Havelyoulundergonelanylsurgery?"
2.l"Havelyouleverlexperiencedltrauma?"
3.l"Arelyoultakinglorallcontraceptives?"
4.l"Arelyoultakinglcalciumlsupplements?"
Answer:
3.lDuringlthelassessment,lthelnurselshouldlasklthelpatientlaboutltheluseloflorallcontraceptives.l
Orallcontraceptiveslinteractlwithlbenzodiazepines,lresultinglinlreducedleliminationloflbenzodiaz
epines.lThislincreaseslthelserumlconcentrationsloflbenzodiazepineslandlthuslcauseslsevereldepr
essionloflthelcentrallnervouslsystem.lSurgerylandltraumalarelnotlcontraindicationslforladministe
ringlbenzodiazepineltolalpatient.lCalciumlsupplementsldolnotlinteractlwithlbenzodiazepines.
Q:lAlpatientldiagnosedlwithldepressionlislstartedlonlaltricycliclantidepressantl(TCA)lafterlfail
ureltolimprovelsymptomslonlalselectivelserotoninlreuptakelinhibitor.lThelnurselshouldlincludel
whichlteachinglpointlwhenleducatinglthelpatientlaboutlthelnewlmedication?
1.lTherelarelnolcontraindicationsltolthislmedication.
2.lThelmedicationlislsafe;litlhaslbeenlusedllongerlthanlmanylothers.
3.lTherelislalrisklofltoxicitylwhenlthislmedicationlisltakenlwithlalcohol.
4.lThislclassloflmedicationslhaslnolotherluselandlislonlylforldepression
Answer:
3.lTherelislanlincreasedlrisklofltoxicitylandlalhighlrateloflmorbiditylwithlTCAslwhenltakenlwit
hlalcohol.
, Q:lThelnurselnotesllithiumlonlalpatient'sldruglhistoryluponladmission.lWhichlconditionlwould
lthelnurselsuspectlthatlthislpatientlhaslbeenldiagnosedlwith?
1.lBipolarldisorder
2.lAbsencelseizures
3.lParanoidlschizophrenia
4.lObsessive-compulsiveldisorder
Answer:
1.lLithiumlislanlantimanicldruglusedltoltreatlmaniclepisodeslassociatedlwithlbipolarldisorder.lT
herapeuticleffectsloflthelmoodlstabilizerllithiumlareldecreasedlmanialandlstabilizationloflthelpat
ient'slmood.lLithiumlislnotlusedltoltreatlabsencelseizures,lparanoidlschizophrenia,lorlobsessive-
compulsiveldisorder.
Q:lAlpatientlislbeinglswitchedlfromlamitriptylineltolcitalopram.lWhichlstatementlmadelbylthe
lpatientlreflectslunderstandingloflpatientleducation?
1.l"IlcanljustlstopltakinglmylElavillandlstartltakinglthelCelexalaslordered."
2.l"IlwilllnotlgetlasldizzylwhenlIlchangelpositionslafterlIlswitchlmedications."
3.l"Theldoctorlislswitchinglmeltolthislmedicationlbecauselitlisllesslexpensivelbutljustlasleffectiv
e."
4.l"IlwilllneedltollimitlmylintakeloflcheeselwhenltakinglCelexaltolpreventlalriselinlmylbloodlpr
essure."
Answer:
2.lCitalopram,lalselectivelserotoninlreuptakelinhibitorl(SSRI),lproduceslminimallanticholinergic
landlcardiovascularlsideleffects.lAgedlcheeselshouldlbelavoidedlbylpatientsltakinglmonoaminel
oxidaselinhibitors,lnotlSSRIs.
Q:lWhichlinstructionldoeslalnurselprovideltolalpatientlwholisltakinglalselectivelserotoninlreup
takelinhibitorl(SSRI)?
1.l"Changelpositionslfrequently."
2.l"Avoidlfoodslorlbeverageslrichlinltyramine."
3.l"Avoidlhotlbaths,lsaunas,landlhotlclimates."
4.l"Increaselthelintakelofldietarylfiberlsupplements."
Answer:
CalculationslandlPharmacology |Qsl&lAs|l
100%lCorrect|lGradelAl(VerifiedlAnswers)
Q:lWhichlanxiolyticldruglpromoteslantagonisticlactivitylatlbothlthelserotoninlandldopaminelre
ceptors?
1.lBuspirone
2.lAlprazolam
3.lLorazepam
4.lAmitriptyline
Answer:
1.lBuspironelislanlanxiolyticldrug,lwhichlhaslagonistlactivitylatlbothlthelserotoninlandldopamin
elreceptorsltolexertlitslantianxietyleffect.lAlprazolamlislalbenzodiazepinelthatlislcommonlylused
laslanlanxiolytic.lTheldruglelicitslitsleffectslbylincreasinglthelactivityloflgamma-
aminobutyriclacidl(GABA)lreceptorslthatlblocklnerveltransmissionlinlthelcentrallnervouslsyste
m.lLorazepamlislanlintermediate-
actinglbenzodiazepinelthatlincreaseslthelactivityloflthelGABAlreceptors.lAmitriptylinelislthelm
ostlcommonlylusedltricycliclantidepressant.
Q:lAlpatientldiagnosedlwithlanlanxietyldisorderlhaslbeenlusingllorazepamlbutlfindslthelsidele
ffectlofldrowsinessltolbelinterferinglwithllife.lWhichlanxiolyticlmedicationslmightlbelalbetterlo
ptionlforlthislpatient?
1.lBuspirone
2.lAlprazolam
3.lChlordiazepoxide
4.lHydroxyzinelhydrochloridelsalt
Answer:
1.lBuspironelislalthird-
generationlanxiolyticlthatlhasltheladvantageloflbeinglbothlnonsedatinglandlnon-habit-
forming.lAlprazolam,lchlordiazepoxide,landlhydroxyzinelhydrochloridelsaltlarelsedativeslaslwel
llaslanxiolytics.
,Q:lAlpatientlwholhasldepressionlislprescribedlduloxetine.lWhichltestslwilllthelnurselsuggestlt
olthelproviderlbeforeltheltherapylislstarted?
1.lRenallfunctionltest
2.lLiverlfunctionltest
3.lCompletelbloodlcount
4.lCompletelurinelexamination
Answer:
2.lDuloxetineltendsltolcauselliverltoxicity;lthereforelalliverlfunctionltestlshouldlbeldonelbeforel
startingltheltherapy.lRenallfunctionltestslmaylnotlbelimportantlbecauseltheldrugldoeslnotlaffectlt
helfunctionloflthelkidneys.lCompletelbloodlcountlandlurinelexaminationlareldoneltolgetlbaselin
elvaluesloflthelbiochemicallparameters,lbutltheselarelnotlimportantltoldeterminelthelprogresslofl
theltherapy.
Q:lAlpatientlwithlattentionldeficitlhyperactivityldisorderlislprescribedlanloralldoselofldiazepa
m.lWhatlislthelmaximumldoselofltheldruglthatlthelpatientlwouldlreceivelinlalday?lRecordlyourl
answerlusinglalwholelnumber.l_____lmglofldiazepamlperlday40
Answer:
30
Theloralldoselofldiazepamlforlalpatientlisl2ltol10lmgltwoltolthreeltimeslperlday.lThereforelthel
maximumldoselofltheldruglthelpatientlwouldlreceivelinlaldaylwouldlbel10lmgl×l3ltimesl=l30lm
g/day.
Q:lWhichlmood-stabilizingldrugslarelusedltoltreatlbipolarldisorder?lSelectlalllthatlapply.
1.lBupropion
2.lImipramine
3.lIsocarboxazid
4.lOxcarbazepine
5.lLithiumlcarbonate
Answer:
4,l5
,Moodlstabilizerslareldrugslthatlarelusedltoltreatlthelcyclesloflmania,lhypomania,landldepression
lbylregulatinglthelmetabolismloflcatecholamines.lExamplesloflmoodlstabilizerslincludeloxcarba
zepinelandllithiumlcarbonate.lImipraminelislaltricycliclantidepressant,lnotlalmoodlstabilizer.lItli
slalsecond-
lineltherapeuticldruglforlbipolarldisorders.lBupropionlislaldruglthatlislcategorizedlunderlalmisce
llaneouslgrouplandlislusedlforltheltreatmentlofldepression.lIsocarboxazidlislalmonoamineloxida
selinhibitorlusedlforltheltreatmentlofldepression.
Q:lThelnurselislassessinglalpatientlwholislprescribedlalbenzodiazepine.lWhenlreviewinglthelp
atient'slhistory,lwhatlmaylthelnurselask?
1.l"Havelyoulundergonelanylsurgery?"
2.l"Havelyouleverlexperiencedltrauma?"
3.l"Arelyoultakinglorallcontraceptives?"
4.l"Arelyoultakinglcalciumlsupplements?"
Answer:
3.lDuringlthelassessment,lthelnurselshouldlasklthelpatientlaboutltheluseloflorallcontraceptives.l
Orallcontraceptiveslinteractlwithlbenzodiazepines,lresultinglinlreducedleliminationloflbenzodiaz
epines.lThislincreaseslthelserumlconcentrationsloflbenzodiazepineslandlthuslcauseslsevereldepr
essionloflthelcentrallnervouslsystem.lSurgerylandltraumalarelnotlcontraindicationslforladministe
ringlbenzodiazepineltolalpatient.lCalciumlsupplementsldolnotlinteractlwithlbenzodiazepines.
Q:lAlpatientldiagnosedlwithldepressionlislstartedlonlaltricycliclantidepressantl(TCA)lafterlfail
ureltolimprovelsymptomslonlalselectivelserotoninlreuptakelinhibitor.lThelnurselshouldlincludel
whichlteachinglpointlwhenleducatinglthelpatientlaboutlthelnewlmedication?
1.lTherelarelnolcontraindicationsltolthislmedication.
2.lThelmedicationlislsafe;litlhaslbeenlusedllongerlthanlmanylothers.
3.lTherelislalrisklofltoxicitylwhenlthislmedicationlisltakenlwithlalcohol.
4.lThislclassloflmedicationslhaslnolotherluselandlislonlylforldepression
Answer:
3.lTherelislanlincreasedlrisklofltoxicitylandlalhighlrateloflmorbiditylwithlTCAslwhenltakenlwit
hlalcohol.
, Q:lThelnurselnotesllithiumlonlalpatient'sldruglhistoryluponladmission.lWhichlconditionlwould
lthelnurselsuspectlthatlthislpatientlhaslbeenldiagnosedlwith?
1.lBipolarldisorder
2.lAbsencelseizures
3.lParanoidlschizophrenia
4.lObsessive-compulsiveldisorder
Answer:
1.lLithiumlislanlantimanicldruglusedltoltreatlmaniclepisodeslassociatedlwithlbipolarldisorder.lT
herapeuticleffectsloflthelmoodlstabilizerllithiumlareldecreasedlmanialandlstabilizationloflthelpat
ient'slmood.lLithiumlislnotlusedltoltreatlabsencelseizures,lparanoidlschizophrenia,lorlobsessive-
compulsiveldisorder.
Q:lAlpatientlislbeinglswitchedlfromlamitriptylineltolcitalopram.lWhichlstatementlmadelbylthe
lpatientlreflectslunderstandingloflpatientleducation?
1.l"IlcanljustlstopltakinglmylElavillandlstartltakinglthelCelexalaslordered."
2.l"IlwilllnotlgetlasldizzylwhenlIlchangelpositionslafterlIlswitchlmedications."
3.l"Theldoctorlislswitchinglmeltolthislmedicationlbecauselitlisllesslexpensivelbutljustlasleffectiv
e."
4.l"IlwilllneedltollimitlmylintakeloflcheeselwhenltakinglCelexaltolpreventlalriselinlmylbloodlpr
essure."
Answer:
2.lCitalopram,lalselectivelserotoninlreuptakelinhibitorl(SSRI),lproduceslminimallanticholinergic
landlcardiovascularlsideleffects.lAgedlcheeselshouldlbelavoidedlbylpatientsltakinglmonoaminel
oxidaselinhibitors,lnotlSSRIs.
Q:lWhichlinstructionldoeslalnurselprovideltolalpatientlwholisltakinglalselectivelserotoninlreup
takelinhibitorl(SSRI)?
1.l"Changelpositionslfrequently."
2.l"Avoidlfoodslorlbeverageslrichlinltyramine."
3.l"Avoidlhotlbaths,lsaunas,landlhotlclimates."
4.l"Increaselthelintakelofldietarylfiberlsupplements."
Answer:
